سامانه مدیریت نشریات علمی دانشگاه علوم پزشکی مشهد

رضائی, نازنین, فرضی, صبا, تقی‌نژاد, حمید, شفیعیان, مهناز, طاهری, صفورا. (1396). کاربرد سلولهای بنیادی در درمان اختلالات تولید مثلی مردان و زنان: مقاله مروری. , 20(ویژه نامه), 78-96. doi: 10.22038/ijogi.2017.9866
نازنین رضائی; صبا فرضی; حمید تقی‌نژاد; مهناز شفیعیان; صفورا طاهری. "کاربرد سلولهای بنیادی در درمان اختلالات تولید مثلی مردان و زنان: مقاله مروری". , 20, ویژه نامه, 1396, 78-96. doi: 10.22038/ijogi.2017.9866
رضائی, نازنین, فرضی, صبا, تقی‌نژاد, حمید, شفیعیان, مهناز, طاهری, صفورا. (1396). 'کاربرد سلولهای بنیادی در درمان اختلالات تولید مثلی مردان و زنان: مقاله مروری', , 20(ویژه نامه), pp. 78-96. doi: 10.22038/ijogi.2017.9866
رضائی, نازنین, فرضی, صبا, تقی‌نژاد, حمید, شفیعیان, مهناز, طاهری, صفورا. کاربرد سلولهای بنیادی در درمان اختلالات تولید مثلی مردان و زنان: مقاله مروری. , 1396; 20(ویژه نامه): 78-96. doi: 10.22038/ijogi.2017.9866

کاربرد سلولهای بنیادی در درمان اختلالات تولید مثلی مردان و زنان: مقاله مروری

مجله زنان، مامایی و نازایی ایران
مقاله 8، دوره 20، ویژه نامه، آذر 1396، صفحه 78-96    اصل مقاله (856.99 K)
نوع مقاله: مروری
شناسه دیجیتال (DOI): 10.22038/ijogi.2017.9866
نویسندگان
نازنین رضائی1؛ صبا فرضی2؛ حمید تقی‌نژاد3؛ مهناز شفیعیان4؛ صفورا طاهری* 5
1کارشناس ارشد مامایی، مرکز تحقیقات تعیین کننده‌های اجتماعی سلامت، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی ایلام، ایلام، ایران.
2دانشجوی دکترای تخصصی پرستاری، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران.
3استادیار گروه پرستاری، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی ایلام، ایلام، ایران.
4کارشناس ارشد مامایی، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی ایلام، ایلام، ایران.
5دانشجوی دکترای تخصصی بهداشت باروری، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی تهران، تهران، ایران. کارشناس ارشد مامایی، دانشکده پرستاری و مامایی، دانشگاه علوم پزشکی ایلام، ایلام، ایران.
چکیده
مقدمه: سلول‌های بنیادی به آن دسته از سلول‌های بدن اطلاق می‌شود که هنوز تمایز نیافته و دارای قدرت خود تکثیری بوده و قابلیت تمایز و تبدیل به انواع دیگر سلول‌های بدن را دارند. با توجه به اهمیت و حساسیت باروری در جوامع بشری و تلاش جهت چاره‌جویی برای کاهش اختلالات باروری در مردان و زنان، مطالعه مروری حاضر با هدف بررسی کاربرد سلول­های بنیادی در درمان اختلالات تولیدمثلی زنان و مردان انجام شد.
روش‌کار: در این مطالعه مروری، اطلاعات مربوط به کاربرد سلول­های بنیادی در درمان اختلالات تولید مثلی مردان و زنان از پایگاه‌های اطلاعاتی نظیر SID، Magiran، PubMed، Irandoc، Iranmedx Scopus، Google Scholar  و web of science با استفاده از کلید واژه­های فارسی: سلول‌های بنیادی، اختلالات تولیدمثلی، مردان و زنان و کلید واژه­های انگلیسی women، reproductive disordersmen، stem cell و infertility بدون محدودیت زمانی جستجو شد. تجزیه و تحلیل داده­ها به صورت کیفی انجام شد. در نهایت برای تنظیم مقاله از 48 مقاله به زبان فارسی و انگلیسی استفاده گردید.
یافته‌ها: استفاده از سلول­های بنیادی تخمدان و رحم و سلول‌های بنیادی اسپرماتوگونیال در درمان ناباروری ناشی از شیمی‌درمانی، بیماری­های اتوایمیون، بیماری­های مرتبط با کروموزوم X، خطرات محیطی، اندومتریوز نوجوانی یا کیست­های تخمدانی و کانسرهای تخمدانی قبل از یائسگی، حفظ باروری، پیشگیری از انتقال بیماری‌های ژنتیکی از کاربردهای سلول­های بنیادی در علوم پزشکی می­باشد که تعدادی از آنها در حیوانات و انسان و تعدادی دیگر فقط در حیوانات مورد بررسی و تأیید قرار گرفته است.
نتیجه‌گیری: سلول­های بنیادی می­توانند در درمان اختلالات تولیدمثلی زنان و مردان کاربردهای بسیاری داشته باشند، حال آنکه در مسیر استفاده از سلول­های بنیادی در نمونه­های انسانی چالش­های تکنیکی و اخلاقی وجود دارد که نیازمند تأمل بیشتری می­باشد.
کلیدواژه‌ها
حفظ باروری؛ ناباروری؛ سلول‌های بنیادی؛ زنان؛ مردان
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