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Banezhad, Farnaz, Ayati, Narjess, Seilanian Toosi, Farrokh, Boloursaz, Samineh, Zakavi, Seyed Rasoul. (1396). Extraosseous accumulation of Technetium-99m-Methyl Diphosphonate (99mTc-MDP) in a child with ALL: A Case Report. , 6(1), 57-60. doi: 10.22038/aojnmb.2017.9679
Farnaz Banezhad; Narjess Ayati; Farrokh Seilanian Toosi; Samineh Boloursaz; Seyed Rasoul Zakavi. "Extraosseous accumulation of Technetium-99m-Methyl Diphosphonate (99mTc-MDP) in a child with ALL: A Case Report". , 6, 1, 1396, 57-60. doi: 10.22038/aojnmb.2017.9679
Banezhad, Farnaz, Ayati, Narjess, Seilanian Toosi, Farrokh, Boloursaz, Samineh, Zakavi, Seyed Rasoul. (1396). 'Extraosseous accumulation of Technetium-99m-Methyl Diphosphonate (99mTc-MDP) in a child with ALL: A Case Report', , 6(1), pp. 57-60. doi: 10.22038/aojnmb.2017.9679
Banezhad, Farnaz, Ayati, Narjess, Seilanian Toosi, Farrokh, Boloursaz, Samineh, Zakavi, Seyed Rasoul. Extraosseous accumulation of Technetium-99m-Methyl Diphosphonate (99mTc-MDP) in a child with ALL: A Case Report. , 1396; 6(1): 57-60. doi: 10.22038/aojnmb.2017.9679

Extraosseous accumulation of Technetium-99m-Methyl Diphosphonate (99mTc-MDP) in a child with ALL: A Case Report

Asia Oceania Journal of Nuclear Medicine and Biology
مقاله 8، دوره 6، شماره 1، فروردین 2018، صفحه 57-60    اصل مقاله (732.34 K)
نوع مقاله: Case report
شناسه دیجیتال (DOI): 10.22038/aojnmb.2017.9679
نویسندگان
Farnaz Banezhad1؛ Narjess Ayati2؛ Farrokh Seilanian Toosi3؛ Samineh Boloursaz3؛ Seyed Rasoul Zakavi* 4
1Nuclear Medicine Research Center, mashhad University of Medical Sciences, Mashhad, Iran
2Nuclear Medicine Research Center, Mashhad University of Medical Science
3Department of Radiology, Mashhad University of Medical Sciences, Mashhad, Iran
4Nuclear Medicine Research Center, Mashhad University of Medical Sciences
چکیده
Extraosseous accumulation of technetium-99m-methyl diphosphonate (99mTc-MDP) on bone scan is not common. This phenomenon is often attributed to abnormality of calcium metabolism and has been reported in a variety of conditions including metabolic diseases and malignancies.
A five years old boy is presented here, who was admitted to the pediatric emergency suffering from fatigue, respiratory symptoms, weight loss, intermittent fevers, anorexia, nausea and vomiting, edema of legs and abdominal distension for one month. The initial laboratory analysis revealed hypercalcemia. The patient was referred for whole body bone scan with suspicion of malignancy and bone metastasis. The bone scan revealed highly increased radiotracer uptake in both lungs in the perfusion and blood pool phases. Delayed images also showed increased activity in lungs and gastric wall. The skeleton was not seen clearly. Bone marrow aspiration was done and established the diagnosis of ALL. The patient deceased due to respiratory failure 20 days later.
Diffuse lung uptake in this patient was consistent with respiratory failure and poor prognosis. It is reported that bone scan may be useful for assessment of the extent of metastatic calcification and may establish suitable management to prevent organ failure.
کلیدواژه‌ها
acute lymphoblastic leukemia؛ technetium-99m-methyl diphosphonate(99mTC-MDP)؛ Bone scan؛ lung uptake؛ hypercalcemia
مراجع

 

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