Ayoobi, Fatemeh, Shamsizadeh, Ali, Fatemi, Iman, Vakilian, Alireza, Allahtavakoli, Mohammad, Hassanshahi, Gholamhossein, Moghadam-Ahmadi, Amir. (1396). Bio-effectiveness of the main flavonoids of Achillea millefolium in the pathophysiology of neurodegenerative disorders- a review. , 20(6), 604-612. doi: 10.22038/ijbms.2017.8827
Fatemeh Ayoobi; Ali Shamsizadeh; Iman Fatemi; Alireza Vakilian; Mohammad Allahtavakoli; Gholamhossein Hassanshahi; Amir Moghadam-Ahmadi. "Bio-effectiveness of the main flavonoids of Achillea millefolium in the pathophysiology of neurodegenerative disorders- a review". , 20, 6, 1396, 604-612. doi: 10.22038/ijbms.2017.8827
Ayoobi, Fatemeh, Shamsizadeh, Ali, Fatemi, Iman, Vakilian, Alireza, Allahtavakoli, Mohammad, Hassanshahi, Gholamhossein, Moghadam-Ahmadi, Amir. (1396). 'Bio-effectiveness of the main flavonoids of Achillea millefolium in the pathophysiology of neurodegenerative disorders- a review', , 20(6), pp. 604-612. doi: 10.22038/ijbms.2017.8827
Ayoobi, Fatemeh, Shamsizadeh, Ali, Fatemi, Iman, Vakilian, Alireza, Allahtavakoli, Mohammad, Hassanshahi, Gholamhossein, Moghadam-Ahmadi, Amir. Bio-effectiveness of the main flavonoids of Achillea millefolium in the pathophysiology of neurodegenerative disorders- a review. , 1396; 20(6): 604-612. doi: 10.22038/ijbms.2017.8827

Bio-effectiveness of the main flavonoids of Achillea millefolium in the pathophysiology of neurodegenerative disorders- a review

Iranian Journal of Basic Medical Sciences
مقاله 1، دوره 20، شماره 6، 2017، صفحه 604-612    اصل مقاله (1.11 M)
نوع مقاله: Review Article
شناسه دیجیتال (DOI): 10.22038/ijbms.2017.8827
نویسندگان
Fatemeh Ayoobi1؛ Ali Shamsizadeh1، 2؛ Iman Fatemi1، 2؛ Alireza Vakilian3، 4؛ Mohammad Allahtavakoli1، 2؛ Gholamhossein Hassanshahi5؛ Amir Moghadam-Ahmadi* 4، 6
1Physiology-Pharmacology Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
2Department of Physiology and Pharmacology, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
3Geriatric Care Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
4Department of Neurology, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
5Pistachio Safety Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
6Non-communicable Diseases Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
چکیده
The Achillea millefolium L. (Yarrow) is a common herb which is widely being used, worldwide. Achillea is being used for treatment of many disorders since centuries. It is considered safe for supplemental use and flavonoids such as kaempferol, luteolin and apigenin are of main constituents present in Achillea. Most of both antioxidant and anti-inflammatory properties of this herb have been attributed to its flavonoid content. Oxidative and inflammatory processes play important roles in pathogenesis of neurodegenerative diseases. Present review was aimed to review the latest literature evidences regarding application of Achillea and/or its three main flavonoid constituents on epilepsy, Alzheimer's disease, multiple sclerosis, Parkinson's disease and stroke.
کلیدواژه‌ها
Achillea millefolium؛ Flavonoids؛ Medicinal؛ Neurodegenerative disease؛ Plants
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