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Sadeghi Bojd, Simin, Soleimani, Gholamreza, Teimouri, Alireza, Zarifi, Elham, Rashidi, Somaye. (1396). Evaluation of Antibiotic Sensitivity of Urinary Tract Pathogens among Children in Zahedan, South East of Iran. , 5(10), 5965-5974. doi: 10.22038/ijp.2017.22970.1924
Simin Sadeghi Bojd; Gholamreza Soleimani; Alireza Teimouri; Elham Zarifi; Somaye Rashidi. "Evaluation of Antibiotic Sensitivity of Urinary Tract Pathogens among Children in Zahedan, South East of Iran". , 5, 10, 1396, 5965-5974. doi: 10.22038/ijp.2017.22970.1924
Sadeghi Bojd, Simin, Soleimani, Gholamreza, Teimouri, Alireza, Zarifi, Elham, Rashidi, Somaye. (1396). 'Evaluation of Antibiotic Sensitivity of Urinary Tract Pathogens among Children in Zahedan, South East of Iran', , 5(10), pp. 5965-5974. doi: 10.22038/ijp.2017.22970.1924
Sadeghi Bojd, Simin, Soleimani, Gholamreza, Teimouri, Alireza, Zarifi, Elham, Rashidi, Somaye. Evaluation of Antibiotic Sensitivity of Urinary Tract Pathogens among Children in Zahedan, South East of Iran. , 1396; 5(10): 5965-5974. doi: 10.22038/ijp.2017.22970.1924

Evaluation of Antibiotic Sensitivity of Urinary Tract Pathogens among Children in Zahedan, South East of Iran

Journal of Pediatric Perspectives
مقاله 20، دوره 5، شماره 10 - شماره پیاپی 46، دی 2017، صفحه 5965-5974    اصل مقاله (383.37 K)
شناسه دیجیتال (DOI): 10.22038/ijp.2017.22970.1924
نویسندگان
Simin Sadeghi Bojd1؛ Gholamreza Soleimani1؛ Alireza Teimouri* 1؛ Elham Zarifi2؛ Somaye Rashidi3
1Children and Adolescents Health Research Center, Zahedan University of Medical Sciences, Zahedan, Iran.
2Medical School, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
3Pediatric Assistant of Zahedan University of Medical Sciences, Zahedan, Iran.
چکیده
Background
Urinary tract infection (UTI), are the most frequent and serious infection in childhood around the world. The present study aimed to evaluate antibiotic sensitivity of urinary tract pathogens among children in Zahedan, South East Iran.
Materials and Methods
This cross-sectional study analyzed 396 patients aged 1-18 years with positive urine and suspected UTI. Gender and age of children, kind of isolated bacteria in urine culture, susceptibility and resistance of these bacteria to current antibiotics were studied. Bacterial growth for more than 105 CFU/ml was considered as positive. Data analyzed by SPSS version 21.0.
Results
The most common age of urinary tract infection were < 1 year and 1-7 years for boys and girls, respectively, and the variation of sex distribution was significant in different age groups (P = 0.003). The most prevalent cause of UTI was Escherichia coli(E.coli) (77%), in total ages and both gender, afterward was Enterobacter (8.1%) and Klebsiella (7.1%). E.coli sepsis was highly sensitive to nitrofurantoin (74.7%), ciprofloxacin (72.5%), and amikacin (64.6%), both highly resistant to trimethoprim and sulfametoxazole (74.8%), ampicillin (66.9%), and nalidixic acid(51.1%); and its resistance to ceftriaxone was increasing.
Conclusion
 In this study resulted that E. coli was the first responsible pathogen in proven culture of UTI in children, which was increased in resistance to popular antibiotics like Ampicillin, Sulfamethoxazole-trimethoprimand Nalidixic acid. In several countries, emphasize the need for local population specific surveillance for guiding empirical therapy for UTI in children.
کلیدواژه‌ها
Antibiotic؛ Bacteria؛ Children؛ Urinary tract infection
آمار
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