Neamati, Ali, Boskabady, Mohammad Hossein, Mohaghegh Hazrati, Saleh, Khakzad, Mohammad Reza, Moosavi, Shakeeb Hassan. (1392). The effect of natural adjuvants (G2, G2F) on lung inflammation of sensitized guinea pigs. , 3(4), 364-370. doi: 10.22038/ajp.2013.812
Ali Neamati; Mohammad Hossein Boskabady; Saleh Mohaghegh Hazrati; Mohammad Reza Khakzad; Shakeeb Hassan Moosavi. "The effect of natural adjuvants (G2, G2F) on lung inflammation of sensitized guinea pigs". , 3, 4, 1392, 364-370. doi: 10.22038/ajp.2013.812
Neamati, Ali, Boskabady, Mohammad Hossein, Mohaghegh Hazrati, Saleh, Khakzad, Mohammad Reza, Moosavi, Shakeeb Hassan. (1392). 'The effect of natural adjuvants (G2, G2F) on lung inflammation of sensitized guinea pigs', , 3(4), pp. 364-370. doi: 10.22038/ajp.2013.812
Neamati, Ali, Boskabady, Mohammad Hossein, Mohaghegh Hazrati, Saleh, Khakzad, Mohammad Reza, Moosavi, Shakeeb Hassan. The effect of natural adjuvants (G2, G2F) on lung inflammation of sensitized guinea pigs. , 1392; 3(4): 364-370. doi: 10.22038/ajp.2013.812

The effect of natural adjuvants (G2, G2F) on lung inflammation of sensitized guinea pigs

Avicenna Journal of Phytomedicine
مقاله 9، دوره 3، شماره 4، 2013، صفحه 364-370    اصل مقاله (202.43 K)
نوع مقاله: Original Research Article
شناسه دیجیتال (DOI): 10.22038/ajp.2013.812
نویسندگان
Ali Neamati1؛ Mohammad Hossein Boskabady* 2؛ Saleh Mohaghegh Hazrati3؛ Mohammad Reza Khakzad4؛ Shakeeb Hassan Moosavi5
1Department of Biology, Faculty of Science, Islamic Azad University, Mashhad Branch, I. R. Iran
2Applied Physiology Research Centre and Department of Physiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, I. R. Iran
3School of Public Health, Tehran University of Medical Sciences and Researches on Industrial Biotechnology, Tehran, I. R. Iran
4Islamic Azad University, Mashhad Branch, and Zakaria Reserch Center, Mashhad, I. R. Iran
5Faculty of Medicine, NHLI, Imperial College, London, UK
چکیده
Objective: The effects of natural adjuvants were examined on total and differential WBC counts in lung lavage of sensitized guinea pigs.
Materials and Methods: In three sensitized groups of guinea pigs including: untreated sensitized animals (S), sensitized animals treated with adjuvant G2 (S+G2) and G2F (S+G2F) as well as non-sensitized group (C) (n=6 for each group), total and differential WBC counts of lung lavage were examined. Sensitization of animals was achieved by injection and inhalation of ovalbumin (OA).
Results: The results showed increased total WBC, eosinophil, neutrophil, and basophil counts, and decreased lymphocytes in lung lavage of sensitized animals compared with the control group (pConclusion: These results indicate important preventive effects of two natural adjuvants, especially G2, on lung inflammation of sensitized guinea pigs.
 
کلیدواژه‌ها
Asthma؛ Natural adjuvant؛ Sensitized animals؛ WBC
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