The Prevalence of Celiac Disease in Children with Unexplained Failure to Thrive in South West of Iran | ||
Journal of Pediatric Perspectives | ||
مقاله 2، دوره 5، شماره 4 - شماره پیاپی 40، تیر 2017، صفحه 4663-4669 اصل مقاله (564.03 K) | ||
شناسه دیجیتال (DOI): 10.22038/ijp.2016.20691.1728 | ||
نویسندگان | ||
Mehri Taheri1؛ Sara Sabzali2؛ Ashrafalsadat Hakim* 3؛ Nooshin Sajadi4؛ Mehran Hakimzade5؛ Tahereh Ziaieikajbaf6؛ Bahman Cheraghian7 | ||
1Assistant Professor of Pediatric, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. | ||
2Pediatrician, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. | ||
3Nursing Care Research Center in Chronic Diseases, School of Nursing and Midwifery, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. | ||
4Assistant Professor of Pediatric Gastroenterology, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. | ||
54Assistant professor of Pediatric Gastroenterology, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. | ||
6Associate Professor of Pediatric, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. | ||
7Assistant Professor, Department of Epidemiology, School of Public Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. | ||
چکیده | ||
Background Celiac disease (CD), considered as a common chronic and genetic diseases that caused by hypersensitivity to gluten. Failure to thrive (FTT), is one of three major clinical features of CD during childhood. The current study aimed to determine the prevalence of celiac disease in children with unexplained FTT in South West of Iran. Materials and Methods This cross‑sectional study was conducted on 433 children 9-month to 6 years old that diagnosed as unexplained FTT referred to Abuzar Children's Hospital, Ahvaz, South West of Iran, in 2014. In this study, we examined the serum levels of anti-transglutaminase antibody (anti-tTG) in children with unexplained FTT. Data were analyzed using SPSS version 16.0 software. Results The results showed that the prevalence of CD in children with unexplained FTT in was 8.8%. The mean scores of children's anti-tTG serum levels in both gender and age groups, showed no significant difference (P> 0.05). Conclusion At current study, the prevalence of CD in children with FTT was 8.8%. Since the CD is an important cause of unexplained FTT in children, the early screening and diagnosis and dietary management can be decrease the risk for long-term complications in these children. | ||
کلیدواژهها | ||
Celiac disease؛ Children؛ Iran؛ Failure to Thrive؛ Prevalence | ||
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