Neonatal Infections: a 5-Year Analysis in a Neonatal Care Unit in North East of Iran | ||
| Journal of Pediatric Perspectives | ||
| مقاله 4، دوره 4، شماره 12 - شماره پیاپی 36، اسفند 2016، صفحه 3989-3998 اصل مقاله (485.03 K) | ||
| شناسه دیجیتال (DOI): 10.22038/ijp.2016.7893 | ||
| نویسندگان | ||
| Hassan Boskabadi1؛ Gholamali Maamouri2؛ Javad Akhodian2؛ Maryam Zakerihamidi3؛ Seyed Javad Sayedi* 4؛ Kiarash Ghazvini5؛ Mohammad Ali Kiani6؛ Abbas Boskabadi7؛ Tayebeh Reyhani8؛ Soheila Karbandi8؛ Hamidreza Behnam Vashani8؛ Naghmeh Razaghi8؛ Maryam Kalateh Mollaei8؛ Zahra Parvini9؛ Tahereh Skandari9؛ Akram Rezaeian8؛ Fatemeh Bagheri10 | ||
| 1Associate Professor, Department of Pediatrics, Mashhad University of Medical Sciences, Mashhad, Iran | ||
| 2Professor, Department of Pediatrics, Mashhad University of Medical Sciences, Mashhad, Iran. | ||
| 3PhD in Reproductive Health, Department of Midwifery, Tonekabon Branch, Islamic Azad University, Tonekabon, Iran. | ||
| 4Assistant Professor, Department of Pediatrics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. | ||
| 5Department of Microbiology and Virology, Antimicrobial Resistance Research Center, Avicenna Research Institute, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. | ||
| 6Associate Professor, Pediatric Gastrointestinal Department of Mashhad University of Medical Sciences, Mashhad, Iran. | ||
| 7Fellowship of Neonatology, Department of Pediatrics, Mashhad University of Medical Sciences, Mashhad, Iran | ||
| 8Department of Pediatric Nursing, Faculty of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran | ||
| 9Faculty of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran. | ||
| 10MSc. in Neonatal Intensive Care, Faculty member of Azad University, Mashhad, Iran. | ||
| چکیده | ||
| Background: Neonatal infections are one of the major causes of death in Iran. Since identifying the risk factors, types, site, bacterial causes, and case fatality rate of an infection can be effective in selecting preventive and therapeutic methods, and appropriate supportive measures, this study aimed to investigate the aforementioned factors in the neonatal intensive care unit (NICU) of Ghaem Hospital in Mashhad- Iran during a 5-year period. Materials and Methods: This cross-sectional study was conducted from Jan 2010 to Jun 2016 on 221 infants diagnosed with infections (positive blood, cerebrospinal fluid, or urine cultures, and radiographic evidence of lung infection as well as laboratory and clinical evidence of infection). Data collection tools consisted of a researcher-made questionnaire including maternal and neonatal characteristics and clinical and laboratory evaluation. Moreover, the infants were followed up until hospital discharge or death. Data were analyzed using SPSS-16. Results: The incidence of neonatal infection was 11.6%. About 70% of the infants were born preterm and 52% of the infected infants were born by cesarean. The most common pathogens of sepsis were gram-negative bacteria (55%), coagulase-negative staphylococci (35%) and other gram-positive bacteria (10%). There were three main causes of infection of central nervous system (CNS): Klebsiella (66%), Escherichia coli (17%), and Acinetobacter (17%). Infant mortality rate due to infection was 28.1%. The causes of death included meningitis (60%), sepsis (27%), and UTI (16%). Conclusion: According to our study, the prevalence of infection and mortality rate in our ward is higher compared to developed countries. The most common cause of infections was gram-negative bacteria, but coagulase-negative staphylococci become more prevalent and needs more attention. | ||
| کلیدواژهها | ||
| Iran؛ Neonatal infections؛ Neonatal Intensive Care Unit؛ Mortality؛ Sepsis | ||
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