Karami, Manoochehr, Haghighi, Bahram, Soltanian, Alireza, Khosravi, Ardashir. (1395). Potentially Preventable Number of Cases and Deaths Associated with Pneumococcal Diseases and Haemophilus Influenzae in Iran during (2010-2013). , 5(2), 4395-4405. doi: 10.22038/ijp.2016.7752
Manoochehr Karami; Bahram Haghighi; Alireza Soltanian; Ardashir Khosravi. "Potentially Preventable Number of Cases and Deaths Associated with Pneumococcal Diseases and Haemophilus Influenzae in Iran during (2010-2013)". , 5, 2, 1395, 4395-4405. doi: 10.22038/ijp.2016.7752
Karami, Manoochehr, Haghighi, Bahram, Soltanian, Alireza, Khosravi, Ardashir. (1395). 'Potentially Preventable Number of Cases and Deaths Associated with Pneumococcal Diseases and Haemophilus Influenzae in Iran during (2010-2013)', , 5(2), pp. 4395-4405. doi: 10.22038/ijp.2016.7752
Karami, Manoochehr, Haghighi, Bahram, Soltanian, Alireza, Khosravi, Ardashir. Potentially Preventable Number of Cases and Deaths Associated with Pneumococcal Diseases and Haemophilus Influenzae in Iran during (2010-2013). , 1395; 5(2): 4395-4405. doi: 10.22038/ijp.2016.7752

Potentially Preventable Number of Cases and Deaths Associated with Pneumococcal Diseases and Haemophilus Influenzae in Iran during (2010-2013)

Journal of Pediatric Perspectives
مقاله 14، دوره 5، شماره 2 - شماره پیاپی 38، 2017، صفحه 4395-4405    اصل مقاله (533.04 K)
شناسه دیجیتال (DOI): 10.22038/ijp.2016.7752
نویسندگان
Manoochehr Karami1؛ Bahram Haghighi* 2؛ Alireza Soltanian3؛ Ardashir Khosravi4
1Modeling of Non communicable Diseases Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.
2Department of Epidemiology, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran.
3Department of Biostatistics, School of Public Health, Modeling of Noncommunicable Diseases Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.
4Ministry of Health and Medical Education, cardiovascular Research Center, Tehran University of Medical Sciences, Iran.
چکیده
Background: Streptococcus pneumoniae and Haemophilus influenzae type b (Hib) is a leading cause of bacterial pneumonia, meningitis, and sepsis in children under 5-year of age. This study aims to estimate potentially preventable number of cases and deaths caused by Hib and pneumococcal in Iran.
Materials and Methods:We used the burden of diseases model estimates of the World Health Organization (WHO) to calculate the number of cases and deaths caused by Streptococcus pneumoniae and Haemophilus influenzae in children less than 5 years old. Efficacy of Hib and pneumococcal vaccine was obtained from literature. Vaccine coverage was cited of published report from Ministry of Health and Medical Education Iran (National Committee on Immunization). Hib and Streptococcus pneumoniae diseases burden was obtained from the WHO global burden of disease project.
Results: We found that  the number of potentially preventable cases and deaths from meningitis caused by Hib among under five years old children in 2013 were 5,414 (95% confidence intervals [CI]: 2838, 11630), and 61 (95% CI: 31, 93), respectively. Estimated number of Streptococcus pneumoniae related pneumonia cases in 2010 and 2013 were 37,732 (95% CI: 22,183, 58,334), and 30,728 (95% CI: 17,023, 50,412), respectively. The corresponding values for pneumonia related deaths from Streptococcus pneumonia were 438 (95% CI: 257, 677), in 2010 and 356 (95% CI: 197, 586), in 2013.
Conclusions: Findings favor the effects of both Hib and Pneumococcal conjugate vaccine (PCV) in reducing the burden of disease and death in Iran. Policy makers are advised to introduce PCV to National immunization program.
کلیدواژه‌ها
Children؛ Iran؛ Haemophilus influenzae type b؛ Immunization؛ Streptococcus pneumoniae
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