سامانه مدیریت نشریات علمی دانشگاه علوم پزشکی مشهد

Ebrahimi, Neda, Taheri, Fatemeh, Moodi, Mitra, Zardast, Mahmoud. (1395). Compare the Relative Frequency of Thyroid Function Disorders in Obese and Overweight Children with Non-Obese Children; a Case-Control Study. , 4(12), 4021-4031. doi: 10.22038/ijp.2016.7605
Neda Ebrahimi; Fatemeh Taheri; Mitra Moodi; Mahmoud Zardast. "Compare the Relative Frequency of Thyroid Function Disorders in Obese and Overweight Children with Non-Obese Children; a Case-Control Study". , 4, 12, 1395, 4021-4031. doi: 10.22038/ijp.2016.7605
Ebrahimi, Neda, Taheri, Fatemeh, Moodi, Mitra, Zardast, Mahmoud. (1395). 'Compare the Relative Frequency of Thyroid Function Disorders in Obese and Overweight Children with Non-Obese Children; a Case-Control Study', , 4(12), pp. 4021-4031. doi: 10.22038/ijp.2016.7605
Ebrahimi, Neda, Taheri, Fatemeh, Moodi, Mitra, Zardast, Mahmoud. Compare the Relative Frequency of Thyroid Function Disorders in Obese and Overweight Children with Non-Obese Children; a Case-Control Study. , 1395; 4(12): 4021-4031. doi: 10.22038/ijp.2016.7605

Compare the Relative Frequency of Thyroid Function Disorders in Obese and Overweight Children with Non-Obese Children; a Case-Control Study

Journal of Pediatric Perspectives
مقاله 6، دوره 4، شماره 12 - شماره پیاپی 36، اسفند 2016، صفحه 4021-4031    اصل مقاله (638.91 K)
شناسه دیجیتال (DOI): 10.22038/ijp.2016.7605
نویسندگان
Neda Ebrahimi1؛ Fatemeh Taheri* 2؛ Mitra Moodi3؛ Mahmoud Zardast4
1Student Research Committee, Resident of pediatrics, Birjand University of Medical Sciences (BUMS), Iran.
2Professor, Birjand Atherosclerosis and Coronary Artery Research Center, Department of pediatrics, Faculty of Medicine, Birjand University of Medical Sciences (BUMS), Birjand, Iran
3Social Determinants of Health Research Center, Department of Health Education, Health School, Birjand University of Medical Sciences (BUMS), Birjand, Iran
4Assistant Professor, Birjand Atherosclerosis and Coronary Artery Research Center, Department of Pathology, Faculty of Medicine, Birjand University of Medical Sciences (BUMS), Birjand, Iran.
چکیده
Background
Childhood obesity has become a global epidemic. In the recent studies has reported risk of thyroid dysfunction due to obesity. Therefore, this study intends to compare the relative frequency of thyroid function disorders in obese and overweight children with non-obese children.
Materials and Methods
This case-control study during 2015 to 2016 in Birjand, Iran was done on 137 children and adolescents (6 to 18 years), with overweight and obesity as case group and 137 non-obese subjects as control group. Body mass index (BMI), thyroid stimulating hormone (TSH), free triiodothyronine (FT3) and free thyroxine (FT4) were measured, and analyzed using SPSS software version19.
Results
TSH level in obese children was significantly more (P<0.001), and FT4 (P<0.001) and FT3 levels (P=0.003), less than non-obese subjects. In the control group, 0.73% and in the case group, 2.92% of patients showed hypothyroidism disorder, that difference was not significant (P=0.177). In the control group, there was significant relationship between TSH with FT4 (P <0.001) and FT3 (P <0.001). Moreover, in the case group, there was significant relationship between TSH with FT4 (P <0.001) and FT3 (P = 0.001), and also, between FT4 with FT3 (P <0.001).
Conclusion
Overweight and obesity in children and adolescents can be effect on increase of TSH and decrease of FT4 and FT3. Long-term studies with larger sample size is suggested.
کلیدواژه‌ها
BMI؛ Children؛ Obesity؛ Overweight؛ Thyroid function disorders
آمار
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