Genital Involvement In Pre-Pubertal Pediatric Population: A Rare Aspect of Crohn’s Disease | ||
| Journal of Pediatric Perspectives | ||
| مقاله 5، دوره 4، شماره 9 - شماره پیاپی 33، آذر 2016، صفحه 3399-3404 اصل مقاله (327.42 K) | ||
| شناسه دیجیتال (DOI): 10.22038/ijp.2016.7334 | ||
| نویسندگان | ||
| Qurratul Ann Warsi* 1؛ Meghana Kunduru2؛ Manoochehr Karjoo3؛ Mirza Beg4 | ||
| 1University of California and San Francisco, Department of Epidemiology and Biostatistics, 1825 4th street, Mission Bay, San Francisco, CA 94154, USA. | ||
| 2State University of New York Medical University, Syracuse, NY 13202, USA. | ||
| 3SUNY Upstate Medical University | ||
| 44Associate Professor of Pediatrics, ivision of Pediatric Gastroenterology, Hepatology, and Nutrition, SUNY Upstate Medical University, 750 East Adams Street, Syracuse, NY 13210, USA. | ||
| چکیده | ||
| Crohn’s disease is an inflammatory bowel disease (IBD), characterized by chronic intestinal inflammation that causes the loss of immune tolerance leading to bizarre inflammatory signals and disruption of mucosal barriers. Environmental triggers and interaction of genetic determinants also play an indispensible role. In this case report, we present a pre-pubertal girl with intermittent and refractory genital swelling. We emphasize that Crohn’s disease must be considered in the differential diagnosis of recurrent, non-tender, erythematous and edematous lesions of the genital area. We conclude with future directions for diagnosing and managing vulvar Crohn’s disease in pediatric population. | ||
| کلیدواژهها | ||
| Crohn’s disease (CD)؛ Inflammatory Bowel Disease (IBD)؛ Infliximab؛ Tumor necrosis factor alpha (TNF-α)؛ Vulvar swelling | ||
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