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Gholami, Somayeh, Kamali Asl, Alireza, Aghamiri, Seyed Mahmood, Allahverdi, Mahmood. (1389). Gamma Knife Simulation Using the MCNP4C Code and the Zubal Phantom and Comparison with Experimental Data. , 7(2), 57-63. doi: 10.22038/ijmp.2010.7262
Somayeh Gholami; Alireza Kamali Asl; Seyed Mahmood Aghamiri; Mahmood Allahverdi. "Gamma Knife Simulation Using the MCNP4C Code and the Zubal Phantom and Comparison with Experimental Data". , 7, 2, 1389, 57-63. doi: 10.22038/ijmp.2010.7262
Gholami, Somayeh, Kamali Asl, Alireza, Aghamiri, Seyed Mahmood, Allahverdi, Mahmood. (1389). 'Gamma Knife Simulation Using the MCNP4C Code and the Zubal Phantom and Comparison with Experimental Data', , 7(2), pp. 57-63. doi: 10.22038/ijmp.2010.7262
Gholami, Somayeh, Kamali Asl, Alireza, Aghamiri, Seyed Mahmood, Allahverdi, Mahmood. Gamma Knife Simulation Using the MCNP4C Code and the Zubal Phantom and Comparison with Experimental Data. , 1389; 7(2): 57-63. doi: 10.22038/ijmp.2010.7262

Gamma Knife Simulation Using the MCNP4C Code and the Zubal Phantom and Comparison with Experimental Data

Iranian Journal of Medical Physics
مقاله 6، دوره 7، شماره 2، شهریور 2010، صفحه 57-63    اصل مقاله (348.59 K)
نوع مقاله: Original Paper
شناسه دیجیتال (DOI): 10.22038/ijmp.2010.7262
نویسندگان
Somayeh Gholami* 1؛ Alireza Kamali Asl2؛ Seyed Mahmood Aghamiri2؛ Mahmood Allahverdi3
1M.Sc., Nuclear Engineering Dept., Shahid Beheshti University, Tehran, Iran
2Assistant Professor, Nuclear Engineering Dept., Shahid Beheshti University, Tehran, Iran
3Assistant Professor, Medical Physics Dept., Tehran University, Tehran, Iran
چکیده
Introduction: Gamma Knife is an instrument specially designed for treating brain disorders. In Gamma Knife, there are 201 narrow beams of cobalt-60 sources that intersect at an isocenter point to treat brain tumors. The tumor is placed at the isocenter and is treated by the emitted gamma rays. Therefore, there is a high dose at this point and a low dose is delivered to the normal tissue surrounding the tumor.
Material and Method: In the current work, the MCNP simulation code was used to simulate the Gamma Knife. The calculated values were compared to the experimental ones and previous works. Dose distribution was compared for different collimators in a water phantom and the Zubal brain-equivalent phantom. The dose profiles were obtained along the x, y and z axes.
Result: The evaluation of the developed code was performed using experimental data and we found a good agreement between our simulation and experimental data.
Discussion: Our results showed that the skull bone has a high contribution to both scatter and absorbed dose. In other words, inserting the exact material of brain and other organs of the head in digital phantom improves the quality of treatment planning. This work is regarding the measurement of absorbed dose and improving the treatment planning procedure in Gamma-Knife radiosurgery in the brain.
کلیدواژه‌ها
brain tumor؛ Dose؛ Digital Phantom؛ Gamma Knife؛ MCNP؛ Simulation
آمار
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