Ataei, Neamatollah, Hosseini, Mostafa, Baikpour, Masoud, Ataei, Fatemeh, Bloori Jirandeh, Hosein, Bazargani, Behnaz, Yousefifard, Mahmoud, Abbasi, Arash. (1395). Etiology and Outcome of Chronic Kidney Disease in Iranian Children. , 4(7), 2105-2112. doi: 10.22038/ijp.2016.6977
Neamatollah Ataei; Mostafa Hosseini; Masoud Baikpour; Fatemeh Ataei; Hosein Bloori Jirandeh; Behnaz Bazargani; Mahmoud Yousefifard; Arash Abbasi. "Etiology and Outcome of Chronic Kidney Disease in Iranian Children". , 4, 7, 1395, 2105-2112. doi: 10.22038/ijp.2016.6977
Ataei, Neamatollah, Hosseini, Mostafa, Baikpour, Masoud, Ataei, Fatemeh, Bloori Jirandeh, Hosein, Bazargani, Behnaz, Yousefifard, Mahmoud, Abbasi, Arash. (1395). 'Etiology and Outcome of Chronic Kidney Disease in Iranian Children', , 4(7), pp. 2105-2112. doi: 10.22038/ijp.2016.6977
Ataei, Neamatollah, Hosseini, Mostafa, Baikpour, Masoud, Ataei, Fatemeh, Bloori Jirandeh, Hosein, Bazargani, Behnaz, Yousefifard, Mahmoud, Abbasi, Arash. Etiology and Outcome of Chronic Kidney Disease in Iranian Children. , 1395; 4(7): 2105-2112. doi: 10.22038/ijp.2016.6977

Etiology and Outcome of Chronic Kidney Disease in Iranian Children

Journal of Pediatric Perspectives
مقاله 10، دوره 4، شماره 7 - شماره پیاپی 31، 2016، صفحه 2105-2112    اصل مقاله (488.71 K)
شناسه دیجیتال (DOI): 10.22038/ijp.2016.6977
نویسندگان
Neamatollah Ataei1؛ Mostafa Hosseini2؛ Masoud Baikpour3؛ Fatemeh Ataei4؛ Hosein Bloori Jirandeh1؛ Behnaz Bazargani5؛ Mahmoud Yousefifard6؛ Arash Abbasi* 7
1Pediatric Chronic Kidney Disease Research Center, Tehran University of Medical Sciences, Tehran, Iran.
2Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
3Department of Neurology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
4Department of Nuclear Medicine, Taleghani Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
5Department of Pediatric Nephrology, Children’s Hospital Medical Center, Tehran University of Medical Sciences, Tehran, Iran
6Department of Physiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
7Department of Pediatric Nephrology, Children’s Hospital Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
چکیده
Background
Considering the significant geographical and ethnical differences in pattern of incidence, etiology and outcome of chronic kidney disease (CKD), the present study aimed to assess the etiology and outcome of CKD in Iranian children.
Materials and Methods
In a cross-sectional study etiology and outcome of 372 children aged 3 months to 18 years with CKD was studied during the period 1991 –2014. Children (186 boys, 186 girls) with Stage 3 to 5 CKDs, defined as a glomerular filtration rate below 60 ml/min per 1.73 m2body surface area, were identified.
Results
Etiology was congenital anomalies of the kidney and urinary tract in 125 (33.60%), cystic/ hereditary/ congenital diseases in 91 (24.46%), glomerulopathy in 73(19.62%), and cause unknown in 71 (19.09%) patients. Forty-eight (13.22%) were on conservative treatment, 174(47.93%) had end-stage renal disease (ESRD) with chronic hemodialysis, 24 (6.61%) were on continuous ambulatory peritoneal dialysis. Sixty-eight (18.74%) underwent on renal transplant which was successful in 52 (14.33%) patients but was associated with abnormal renal function in 16(4.41%) children. Finally, 49 (13.50%) patients died.
Conclusion
A large number of children developed CKD secondary to congenital anomalies of the kidney and urinary tract. Planning for screening, early detection and instituting timely treatment of preventable causes could lead to a lower incidence of CKD in this group of children.
کلیدواژه‌ها
Acute kidney injury؛ Etiology؛ Children؛ CAKUT؛ End-stage renal disease
آمار
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