Comparison of the effect of fish oil and vitamin E on the duration of Cyclic mastalgia | ||
| Evidence Based Care | ||
| مقاله 7، دوره 3، شماره 1، تیر 2013، صفحه 69-76 اصل مقاله (170.94 K) | ||
| نوع مقاله: Original Quantitative and Qualitative Research Paper | ||
| شناسه دیجیتال (DOI): 10.22038/ebcj.2013.696 | ||
| نویسندگان | ||
| farzaneh jaafarnejad1؛ seyedeh fatemeh hosseini* 2؛ seyed reza mazlom3؛ maryam hami4 | ||
| 1midwife/mashhad university of medical sciences | ||
| 2Midwife/Mashhad University of Medical Sciences | ||
| 3nurse/mashhad university of medical sciences | ||
| 4doctor/mashhad university of medical sciences | ||
| چکیده | ||
| Background: One of the most common causes of referal of women of childbearing age to physician is the cyclic mastalgia. The present study was performed due to the similar mechanism of action of fish oil and vitamin E in reducing this pain. Aim: To determine the effect of fish oil and vitamin E on duration of Cyclic mastalgia. Methods: This Triple-blind clinical trial was performed on 70 women (15 to 49 years) suffered from cyclical mastalgia. Patients were divided into two study groups with 35 patients in each group, included: 1. Fish oil 3gr/day, 2. Vitamin E 400 unit daily. Breast pain duration was evaluated before the study and 1 and 2 months after the intervention, In addition, medication side effects were assessed after an intervention. Data after collected by registration table of breast pain duration was analysed by SPSS statistical software (version16). Chi-square, repeated measures ANOVA, independent and paired-t tests were performed. Results: The mean of breast pain duration in fish oil group before an intervention was 9/3±3/4 and was decreased to 2/5±4/5 2 months after the fish oil consumption. Also in Vitamin E group this mount decreased from 9/5±3/3 to2/2±3/5. Overally the mean scores of breast pain duration decreased before and after the intervention in both groups (P<0/001). Conclusion: According to the findings of this study and the absence of serious drug side effects, fish oil and Vitamin E with similar therapeutic effects in the treatment of cyclic mastalgia, can be a viable alternative to other hazardous drugs in this field. | ||
| کلیدواژهها | ||
| Fish oils؛ Mastalgia؛ Pain؛ Vitamin E | ||
| مراجع | ||
|
1. OlfatiF, Parsay S, Nahidi SH. Therapeutic Effects of Vitamin E on Cyclic Mastalgia. Breast J 2009؛ 5: 510–4..
2. Alvandipour M,Tayebi P,Alizadeh navaie R,Khodabakhshi H. Comparison Between Effect of Evening Primrose Oil and Vitamin E in Treatment of Cyclic Mastalgia. J Babol Univ Med Sci 2011; 13(2):7-11.
3. Berek J, Novak E. Berek & novaks gynecology.15th ed. United States of America: Lippincott Williams & Wilkins a wolter business؛ 2012.
4. Sekhavat L, Zare tazarjani F, Kholasezadeh P. Effects of Vitex Agnus Herbal Drug on Women Mastalgia. South med Q 2009; 11(2):147-52. (Persian)
5. Ryan K, Berkowitz R, Barbieri R, Dunaif A. Kistners gynecology &womens health.7th ed. United states of America: Mosby ؛1999.
6. Zamani M, Arab M, Nasrollahi SH, Manikashani KH. Therapeutic Effect of Fish Oil on Primary Dysmenorrhea. J Gorgan Univ Med Sci 2005; 7(1):39-42. (Persian)
7. Dolatian M, Jafari H, Velayi N, Afrakhteh M, Taleban F, Gachkar L. Effect of Fish Oil on Primary Dysmenorrhea. J Zanjan Univ Med Sci 2004; 47: 7-14. (Persian)
8. Yaghmaei M, Moradi A, Hosseini R. A Comparison of Therapeutic Effect between Mefenamic Acid and Mefenamic Acid Plus Fish Oil in Reduction of the Sverity of Pain in Primary Dysmenorrhea. J Gillan Univ Med Sci 2004; 13(49):68-73.
9. Blommers J, Klerk E, Kuik D, Bezemer P, Meijer S. Evening Primrose Oil and Fish Oil For Severe Chronic Mastalgia: A Randomized, Double-blind, Controlled Trial. Am J Obstet Gynecol 2002; 187: 1389 -94.
10. Pruthi S, Wahner-Roedler D, Torkelson C, Cha S, Thicke L, Hazelton J, Bauer B. Vitamin E and Evening Primrose Oil for Management of Cyclical Mastalgia: A Randomized Pilot Study. Altern Med Rev 2010; 15(1):59-67.
11. Wall R, Ross P, Fitzgerald G, Stanton C. Fatty Acids from Fish: The Anti-inflammatory Potential of Long-chain Omega-3 Fatty Acids. Nutr Rev 2010; 68(5):280–9. | ||
|
آمار تعداد مشاهده مقاله: 4,384 تعداد دریافت فایل اصل مقاله: 1,520 |
||