Kaviani, D., Koonani, M., Saghi, M., Hosein Bigtan, M.. (1394). Investigation of the effect of different parameters on the phase inversion temperature O/W nanoemulsions. , 3(1), 65-68. doi: 10.7508/nmj.2016.01.008
D. Kaviani; M. Koonani; M. Saghi; M. Hosein Bigtan. "Investigation of the effect of different parameters on the phase inversion temperature O/W nanoemulsions". , 3, 1, 1394, 65-68. doi: 10.7508/nmj.2016.01.008
Kaviani, D., Koonani, M., Saghi, M., Hosein Bigtan, M.. (1394). 'Investigation of the effect of different parameters on the phase inversion temperature O/W nanoemulsions', , 3(1), pp. 65-68. doi: 10.7508/nmj.2016.01.008
Kaviani, D., Koonani, M., Saghi, M., Hosein Bigtan, M.. Investigation of the effect of different parameters on the phase inversion temperature O/W nanoemulsions. , 1394; 3(1): 65-68. doi: 10.7508/nmj.2016.01.008

Investigation of the effect of different parameters on the phase inversion temperature O/W nanoemulsions

Nanomedicine Journal
مقاله 8، دوره 3، شماره 1، 2016، صفحه 65-68    اصل مقاله (96.65 K)
نوع مقاله: Research Paper
شناسه دیجیتال (DOI): 10.7508/nmj.2016.01.008
نویسندگان
D. Kaviani* 1؛ M. Koonani2؛ M. Saghi2؛ M. Hosein Bigtan2
1Young Researchers and Elite Club, East Tehran Branch, Islamic Azad University, Tehran, Iran
2Department of Chemistry, faculty of science, Arak Branch, Islamic Azad University, Arak, Iran
چکیده
Objective(s): Nanoemulsions are a kind of emulsions that can be transparent, translucent (size range 50-200 nm) or “milky” (up to 500 nm). Nanoemulsions are adequatly effective for transfer of active component through skin which facilitate the entrance of the active component . The transparent nature of the system and lack of the thickener and fluidity are among advantages of nanoemulsion.
Materials and Methods: In this study, a nanoemulsion of lemon oil in water was prepared by the phase inversion temperature (PIT) emulsification method in which the tween 40 was used as surfactant. The effect of concentration of NaCl in aqueous phase, pH and weight percent of surfactant and aqueous on the PIT and droplet size were investigated. Results: The results showed that with increasing of concentration of NaCl from 0.05 M to 1 M, PIT decrease from 72 to 50. The average droplet sizes, for 0.1, 0.5 and 1 M of NaCl in 25 ºC are 497.3, 308.1 and 189.9 nm, respectively and the polydispersity indexes are 0.348, 0.334 and 0.307, respectively.
Conclusion: Considering the characteristics of nanoemulsions such as being transparent, endurance of solution and droplet size can provide suitable reaction environment for polymerization process used in making hygienic and medical materials.
کلیدواژه‌ها
Nanoemulsion؛ Phase inversion temperature؛ Surfactant
مراجع
آمار
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