Influence of Sexuality in Functional Recovery after Spinal Cord Injury in rats | ||
| The Archives of Bone and Joint Surgery | ||
| مقاله 11، دوره 4، شماره 1، 2016، صفحه 56-59 اصل مقاله (344.35 K) | ||
| نوع مقاله: RESEARCH PAPER | ||
| شناسه دیجیتال (DOI): 10.22038/abjs.2016.5816 | ||
| نویسندگان | ||
| Mohammadreza Emamhadi1؛ Bahram Soltani* 2؛ Parvin Babaei3؛ Hossein Mashhadinezhad4؛ Shervin Ghadarjani1 | ||
| 1Department of Neurosurgery, Guilan University of Medical Sciences, Rasht, Iran | ||
| 2Department of P harmacology, Cellular and Molecular Research Center, Guilan University of Medical Sciences, Rasht, Iran | ||
| 3Department of Physiology, Cellular and Molecular Research Center, Guilan University of Medical Sciences, Rasht, Iran | ||
| 4Department of Neurosurgery, Ghaem Hospital, Mashhad, Iran | ||
| چکیده | ||
| Background: Spinal cord injury (SCI) is a major clinical condition and research is commonly done to find suitable treatment options. However, there are some degrees of spontaneous recovery after SCI and gender is said to be a contributing factor in recovery, but this is controversial. This study was done to compare the effects of sexual dimorphism on spontaneous recovery after spinal cord injury in Wistar Rats. Methods: Spinal cord lesions were made by compressing the cord at T9 level and making a spinal cord contusion. Routine care of each rat was done daily. The LSS scoring system was used to measure the locomotion of these rats and to compare the recovery rate between male and female rats. Results: The results suggested that there was no significant difference between the two sex in recovery. Conclusions: To be female does not seem to be a prognostic factor for recovery after SCI. However, this preliminary study should be repeated in other animals and in larger cohorts. | ||
| کلیدواژهها | ||
| Gender؛ Rat؛ Spinal cord injury؛ Spontaneous recovery | ||
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