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Emamhadi, Mohammadreza, Soltani, Bahram, Babaei, Parvin, Mashhadinezhad, Hossein, Ghadarjani, Shervin. (1394). Influence of Sexuality in Functional Recovery after Spinal Cord Injury in rats. , 4(1), 56-59. doi: 10.22038/abjs.2016.5816
Mohammadreza Emamhadi; Bahram Soltani; Parvin Babaei; Hossein Mashhadinezhad; Shervin Ghadarjani. "Influence of Sexuality in Functional Recovery after Spinal Cord Injury in rats". , 4, 1, 1394, 56-59. doi: 10.22038/abjs.2016.5816
Emamhadi, Mohammadreza, Soltani, Bahram, Babaei, Parvin, Mashhadinezhad, Hossein, Ghadarjani, Shervin. (1394). 'Influence of Sexuality in Functional Recovery after Spinal Cord Injury in rats', , 4(1), pp. 56-59. doi: 10.22038/abjs.2016.5816
Emamhadi, Mohammadreza, Soltani, Bahram, Babaei, Parvin, Mashhadinezhad, Hossein, Ghadarjani, Shervin. Influence of Sexuality in Functional Recovery after Spinal Cord Injury in rats. , 1394; 4(1): 56-59. doi: 10.22038/abjs.2016.5816

Influence of Sexuality in Functional Recovery after Spinal Cord Injury in rats

The Archives of Bone and Joint Surgery
مقاله 11، دوره 4، شماره 1، فروردین 2016، صفحه 56-59    اصل مقاله (344.35 K)
نوع مقاله: RESEARCH PAPER
شناسه دیجیتال (DOI): 10.22038/abjs.2016.5816
نویسندگان
Mohammadreza Emamhadi1؛ Bahram Soltani* 2؛ Parvin Babaei3؛ Hossein Mashhadinezhad4؛ Shervin Ghadarjani1
1Department of Neurosurgery, Guilan University of Medical Sciences, Rasht, Iran
2Department of P harmacology, Cellular and Molecular Research Center, Guilan University of Medical Sciences, Rasht, Iran
3Department of Physiology, Cellular and Molecular Research Center, Guilan University of Medical Sciences, Rasht, Iran
4Department of Neurosurgery, Ghaem Hospital, Mashhad, Iran
چکیده
 
Background: Spinal cord injury (SCI) is a major clinical condition and research is commonly done to find suitable treatment options. However, there are some degrees of spontaneous recovery after SCI and gender is said to be a contributing factor in recovery, but this is controversial. This study was done to compare the effects of sexual dimorphism on spontaneous recovery after spinal cord injury in Wistar Rats.

Methods: Spinal cord lesions were made by compressing the cord at T9 level and making a spinal cord contusion. Routine care of each rat was done daily. The LSS scoring system was used to measure the locomotion of these rats and to compare the recovery rate between male and female rats.

Results: The results suggested that there was no significant difference between the two sex in recovery.

Conclusions: To be female does not seem to be a prognostic factor for recovery after SCI. However, this preliminary study should be repeated in other animals and in larger cohorts.
کلیدواژه‌ها
Gender؛ Rat؛ Spinal cord injury؛ Spontaneous recovery
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