Traditional Chinese and Indian medicine in the treatment of opioid-dependence: a review | ||
| Avicenna Journal of Phytomedicine | ||
| مقاله 2، دوره 3، شماره 3، شهریور 2013، صفحه 205-215 اصل مقاله (232.41 K) | ||
| نوع مقاله: Review Article | ||
| شناسه دیجیتال (DOI): 10.22038/ajp.2013.514 | ||
| نویسندگان | ||
| Fatemeh Doosti1؛ Saeedeh Dashti1؛ Seyed Meghdad Tabatabai1؛ Hossein Hosseinzadeh* 2 | ||
| 1School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, I. R. Iran | ||
| 2Pharmaceutical Research Center, Department of Pharmacodynamics and Toxicology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, I. R. Iran | ||
| چکیده | ||
| Objective: In this study, the current literatures on the use of herbs and herbal preparations of Traditional Chinese and Indian Medicine for the treatment of opioid addiction were reviewed. Methods: Search was done in databases such as Pub Med, Science Direct, Scopus, Springer Link, and Google Scholar. Results: Among 18 retrieved studies, 3 studies were about asafetida extract, an approved preparation for ameliorating drug abstinence in China. Chinese preparations including Composite Dong Yuan Gao, Qingjunyin and TJ-97 (a water extract of dai-bofu-to) as well as Indian ones, Mentate and Shilajit, were reported to have positive effects against opioid withdrawal, dependence, and tolerance. Moreover, Levo-tetrahydropalmatine and L-Stepholidine, in addition to extracts of Caulis Sinomenii and Sinomenium acutum showed similar effects. Banxia Houpu Decoction, Fu-Yuan pellet, Jinniu capsules, Qingjunyin, Tai-Kang-Ning capsule, and Xuan Xia Qudu Jiaonang (WeiniCom) from Chinese preparations, showed anti-addiction effects in randomized, double-blind and, in some studies, multicenter clinical trials. Conclusion: Traditional herbal preparations of China and India have anti-addiction effects with less adverse effects than alpha2-adrenergic or opioid agonists. | ||
| کلیدواژهها | ||
| Addiction؛ Opioid Tolerance؛ Opioid withdrawal؛ Traditional Chinese Medicine؛ Traditional Indian Medicine | ||
| مراجع | ||
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