Retracted: Effect of Aerobic Exercise on Serum Concentration of Apelin, TNFα and Insulin in Obese Women | ||
| Iranian Journal of Basic Medical Sciences | ||
| مقاله 16، دوره 15، شماره 6، بهمن 2012، صفحه 1196-1201 اصل مقاله (527.83 K) | ||
| نوع مقاله: Retraction | ||
| شناسه دیجیتال (DOI): 10.22038/ijbms.2012.4940 | ||
| نویسندگان | ||
| Shahin Sheibani1؛ Parichehr Hanachi* 2؛ Mohammad Ali Refahiat1 | ||
| 1Departmen of Exercise Physiology, Science and Research Branch, Islamic Azad University, Fars, Iran | ||
| 2Faculty of Sciences, Biology Department, Biochemistry Unit, Alzahra University, Tehran, Iran | ||
| چکیده | ||
| Objective(s) Apelin is novel adipokine acting on APJ receptor, regulated by insulin and tumor necrosis factor-alpha (TNF-alpha). Plasma apelin levels are increased in obese subjects. The aim of this study was to investigate whether or not the aerobic exercise modifies the elevated plasma apelin levels in obese women. Materials and Methods Twenty obese women (BMI 32.2 ± 6.4 kg/m2) were selected by random sampling method among obese women. Twelve healthy women with a BMI of 31.7 ± 0.6 kg/m2 served as control group. The aerobic exercise was performed during 8 weeks, 3 sessions per week. The intensity of the training program proceeded form 50% to 70% in 8 weeks. Results Results showed that plasma levels of apelin and TNFα were higher in obese individuals compared with the control group. The exercise resulted in significant decrease (P<0.05) of BMI to 29.8± 6.3 kg/m2 , plasma insulin (8.16 ± 0.73 to 6.58 ± 0.66 μmol/l), apelin (369 ± 25 pg/ml vs 257 ± 12 pg/ml) and TNFα levels (0.66 ± 0.04 pg/ml vs 0.56 ± 0.04 pg/ml). P< 0.05 was considered statistically significant. Conclusion Exercise can decrease plasma apelin, insulin and TNFα levels in obese women. Regular physical activity causes a decrease in plasma levels of apelin if body mass index and body fat mass simultaneously decreased. | ||
| کلیدواژهها | ||
| aerobic exercise؛ Apelin؛ Insulin؛ Obese women؛ TNFα | ||
| مراجع | ||
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