Comparison of Two Methods for Measurement of HbA1c in Two University Hospitals of Mashhad | ||
Journal of Patient Safety & Quality Improvement | ||
مقاله 6، دوره 3، شماره 3، مهر 2015، صفحه 262-265 اصل مقاله (258.46 K) | ||
نوع مقاله: Original Article | ||
شناسه دیجیتال (DOI): 10.22038/psj.2015.4566 | ||
نویسندگان | ||
Saeid Davari Edalat Panah1؛ Naser Karimian Tousi2؛ Leili Rahimi3؛ Golnaz Sabouri3؛ Ali Mirsalehi3؛ Farnaz Zahedi Avval* 4 | ||
1Central Laboratory, Ghaem Hospital, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. | ||
2Central Laboratory, Emam Reza Hospital, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. | ||
3Patient Safety Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. | ||
4Department of Biochemistry, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. | ||
چکیده | ||
Introduction: The aim of this study was to compare the two analytical techniques for determination of Glycated hemoglobin (HbA1c), consisting immunoturbidimetric and enzymatic methods. Materials and Methods A total of 140 out-patients were included in this study. Measurements of HbA1c were done in blood samples using immunoturbidimetric and enzymatic assay. The two methods were used by clinical laboratories of Ghaem and Emam Reza hospitals in Mashhad, respectively. Results:Our results indicate that there was no significant difference between two methods, though; the average of HbA1c measured by enzymatic method was rather higher than the other method (7.38 and 7.34, respectively). The two methods correlated well with correlation coefficient of 0.967. Conclusion: Both techniques were proved to be sufficiently reliable and the results of the two methods show strong correlation though, the enzymatic method has an additional advantage of simultaneous measuring total Hb which can omit the undesired effect of hemolysis occurring during sampling | ||
کلیدواژهها | ||
HbA1c Immunoturbidimetric Enzymatic assay | ||
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