Allergic Rhinitis in Adults with Chronic Suppurative Otitis Media | ||
| Iranian Journal of Otorhinolaryngology | ||
| مقاله 2، دوره 27، شماره 4، 2015، صفحه 261-266 اصل مقاله (198.88 K) | ||
| نوع مقاله: Original | ||
| شناسه دیجیتال (DOI): 10.22038/ijorl.2015.4518 | ||
| نویسندگان | ||
| Shadman Nemati1؛ Reza Jafari Shakib2؛ Maryam Shakiba3؛ Nematollah Araghi4؛ Seyyede Zeinab Azimi* 1 | ||
| 1Sinonasal Diseases Research Centre, Amiralmomenin Hospital, Guilan University of Medical Sciences, Rasht, Iran. | ||
| 2Department of Immunology, Faculty of Medicine, Guilan University of Medical Sciences, Rasht, Iran. | ||
| 3PhD Candidate, Department of Epidemiology, School of Public Health, Shahid Beheshti University of medical sciences, Tehran, Iran. | ||
| 4Department of Otolaryngology, Amiralmomenin Hospital, Guilan University of Medical Sciences, Rasht, Iran. | ||
| چکیده | ||
| Introduction: Chronic suppurative otitis media (CSOM) is considered one of the most common causes of acquired hearing impairment in developing countries. CSOM is a multifactorial persistent inflammatory disease of the middle ear. A distinct pathophysiologic mechanism linking allergic rhinitis (AR) and CSOM remains to evolve. The purpose of this study was to investigate the association between AR and CSOM in adults.This was a case-control study. Materials and Methods: The subjects were 62 adults (23 male, 39 female) with established CSOM and 61 healthy controls.CSOM was diagnosed when there was a history of chronic (persisting for at least 3 months) otorrhea, accumulation of mucopurulent exudates in the external auditory canal or middle ear and/or perforated tympanic membrane on otoscopy. All participants were evaluated for the presence of AR by clinical evaluation of allergic symptoms, and underwent a skin-prick test for 23 common regional allergens. Statistical analysis was performed using SPSS version 16. Results: The prevalence of clinical rhinitis (allergic and non-allergic) was significantly higher among the cases compared with controls (62.5% vs. 37.5%, P=0.02). The prevalence of AR (proven by positive skin-prick test) was also significantly higher among affected adults than controls (24.6% and 13.8%, respectively). Adjusting for age, a logistic regression model showed that there was a significant difference between the two groups. Patients with AR and non-AR were at 3.27- (95% CI=1.15–9.29; P=0.036) and 2.57-(95% CI=1.01–6.57; P=0.048) fold increased risk of developing CSOM, respectively, compared with healthy individuals. Conclusion: The study showed a higher prevalence of AR in CSOM patients than in controls. It may be valuable to evaluate and control this factor in these patients. | ||
| کلیدواژهها | ||
| Rhinitis؛ Allergic؛ Hypersensitivity؛ Otorhinolaryngologic diseases؛ Otitis media؛ Suppurative؛ Skin test | ||
| مراجع | ||
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