سامانه مدیریت نشریات علمی دانشگاه علوم پزشکی مشهد

Bezheh, Nahid, Soltani, Mahmod, Khaleghzade, Homa. (1393). Effects of aerobic training in water on IL-6 and IL-10 in patients with Multiple Sclerosis. , 4(2), 63-72. doi: 10.22038/ebcj.2014.2912
Nahid Bezheh; Mahmod Soltani; Homa Khaleghzade. "Effects of aerobic training in water on IL-6 and IL-10 in patients with Multiple Sclerosis". , 4, 2, 1393, 63-72. doi: 10.22038/ebcj.2014.2912
Bezheh, Nahid, Soltani, Mahmod, Khaleghzade, Homa. (1393). 'Effects of aerobic training in water on IL-6 and IL-10 in patients with Multiple Sclerosis', , 4(2), pp. 63-72. doi: 10.22038/ebcj.2014.2912
Bezheh, Nahid, Soltani, Mahmod, Khaleghzade, Homa. Effects of aerobic training in water on IL-6 and IL-10 in patients with Multiple Sclerosis. , 1393; 4(2): 63-72. doi: 10.22038/ebcj.2014.2912

Effects of aerobic training in water on IL-6 and IL-10 in patients with Multiple Sclerosis

Evidence Based Care
مقاله 7، دوره 4، شماره 2، مهر 2014، صفحه 63-72    اصل مقاله (189.97 K)
نوع مقاله: Original Quantitative and Qualitative Research Paper
شناسه دیجیتال (DOI): 10.22038/ebcj.2014.2912
نویسندگان
Nahid Bezheh1؛ Mahmod Soltani* 2؛ Homa Khaleghzade3
1Associate Professor of Exercise Physiology, Ferdowsi University of Mashhad, Faculty of Physical Education and Sports Science, Mashhad, Iran
2Faculty Member of Islamic Azad University of Mashhad, Department of Physical Education and Sports Science, Mashhad, Iran
3Master of Exercise Physiology, hakim Sabzevari University of sabzevar, Iran
چکیده
Background: Multiple Sclerosis is the most prevalent disease of the central nerve system. This disease affects different aspects of patient’s life. Multiple Sclerosis has negative effects on physical and mental health. Cytokines play an important role in the pathogenesis of Multiple Sclerosis and are major targets of therapeutic interventions.
Aim: To investigate the effects of aquatic aerobic exercise on IL-6 and IL-10 in men with Multiple Sclerosis.
Methods: In this randomized clinical trial, 30 patients with MS were randomly divided into two control and experimental groups. For experimental group, exercise program was applied for 8 weeks, 3 sessions per week with intensity of 50-60% of maximum heartbeat. IL-6 and IL-10 were analyzed before and after exercises. Analyzing data was done by SPSS ver. 18, and 0.05 significant level of independent T examination.
Results: Results indicated that there was significant difference between the two groups in IL-6 (P<0/001) and IL-10 (P<0/004).
Conclusion: aerobic training in watercan regulate the inflammatory and anti-inflammatory cytokines, and adjust IL-6 and IL-10 indexes. Experts can use these exercises as complementary treatment along with medical cure for MS patients.
کلیدواژه‌ها
IL-6؛ IL-10؛ Multiple Sclerosis؛ Training in water
مراجع
  1.  Hojjatollah N. B, Khosrow E, Reza R. S, & Monire M. N. Effects of Selected Combined Training on Muscle Strength in Multiple Sclerosis Patients. Healthmed. 2012;6: 96-102. (Persian)
  2. Karussis D, Karageorgiou C, Vaknin-Dembinsky A, Gowda-Kurkalli B, Gomori J. M, Kassis I, Bulte J. W. M, et al. Safety and Immunological Effects of Mesenchymal Stem Cell Transplantation in Patients with Multiple Sclerosis and Amyotrophic Lateral Sclerosis. Arch Neurol. 2010; 67 (10): 1187-94.
  3. Masoudnejad M, Ebrahim Kh, Shirvani H. Impactof Selected Combinations of Training on Muscle Strength and Motor Function in Women with Multiple Sclerosis (MS). Sports Physiology. 2012; 16: 81-96. (Persian)
  4. Dalgas U, Stenager E, Jakobsen J, Petersen T, Hansen H. J, Knudsen C, et al. Resistance Training Improves Muscle Strength and Functional Capacity in Multiple Sclerosis. Neurology.2009; 73(18): 1478-84.
  5. Saman-Nezhad B, Rezaee T, Bostani A, Najafi F , Aghaei A. Epidemiological Characteristics of Patients with Multiple Sclerosis in Kermanshah. J Mazand Univ Med Sci. 2013; 23(104): 97-101. (Persian)
  6. Broekmans T, Roelants M, Alders G, Feys P, Thijs H, Eijnde B. O. Exploring the Effects of a 20-Week Whole-Body Vibration Training Programme on Leg Muscle Performance and Function in Persons with Multiple Sclerosis. J Rehabil Med. 2010; 42(9): 866-72.
  7. Maghsoudi N, Khosravi N, Ravaci AA. The Effect of Training (aerobic and strength) of Some Cytokines in Male and Female Patients with MS. Sporting Life Sciences. 2011; 10: 5-23. (Persian) 
  8. Castellano V, Patel D. I, White L. J. Cytokine Responses to Acute and Chronic Exercise in Multiple Sclerosis. J Appl Physiol (1985).  2008; 104(6): 1697-1702.
  9. Ghannadi AR, Sadeghi M. Hopes for the Treatment of Multiple Sclerosis is Fresh Life. Journal of Traditional Medicine in Islam and Iran. 2012; 2 (1): 9-20. (Persian)
  10. AsadiZaker M, Majdinasab M, Atapour M, Latifi M, Babadi M. Effect of Exercise on Walking Speed, Fatigue and Quality of Life in Patients with Multiple Sclerosis. J of Medical. 2010; 9 (2): 189-98. (Persian)
  11. Rasouli N, Ahmadi F, Nabavi SM, Hajizadeh A. The Effect of Keeping Energy Techniques on Fatigue Level of Patients with Multiple Sclerosis. J Rahabil Res. 2006; 24: 43-8. (Persian)
  12. Atashzadeh F, Shiri H, Moshtataqeesheqi Z, Saniei M. Effect of Exercise Training of Activity of Daily Living in Women with Multiple Scloerosis in Iranian Multiple Scloerosis Society. J Rafsanjan Uni Med Sci. 2003; 3-4(2) P: 164-71. (Persian)  
  13. Neill J, Blan I, Ried K. Effectiveness of Non-Pharmacological Interventions for Fatigue in Adults with Multiple Sclerosis, Rheumatoid Arthritis, or Systemic Lupus Erythematosus: A Systematic Review. J Adv Nurs. 2006; 56 (6): 617-35.
  14. Williams K. Strength and Cardiorespiratory Exercise for People with Multiple Sclerosis (MS). MS Australia. 2009.
  15. Dalgas U, Stenager E, and Ingemann-Hansen T. Multiple Sclerosis and Physical Exercise: Recommendations for the Application of Resistance-, Endurance- and Combined Training. Mult Scler. 2008; 14: 35–53.
  16. White L. J, Castellano V, Mc Coy S. C. Cytokine Responses to Resistance Training in People with Multiple Sclerosis. J Sports Sci. 2006; 24(8): 911-14.
  17. Eftekhari A, Nikbakht H, Etemadi Far M, Rabiei K. The Effect of Steady Exercise on Aerobic Ability and Quality of Life in Women with Multiple Sclerosis. J Olympic Acad IR. 2008; 16(1):37-46. (Persian)
  18. Soltani M, Hejazi SM, Noorian A, Zendedel A.The Effect of Aerobic Training on the Improvement of Expanded Disability Status Scale (EDSS) in Multiple Sclerosis Patients. Medical Scirnces Journal of Islamic Azad University of Mashhad25. 2009; (1) 5: 15-20. (Persian)
  19. Soltani  M,  Hejazi  SM,  Noorian  A,  Zendedel  A,  Ashkanifar  M . The Effect of Selected Aerobic Exercise on the Balance Improvement in Multiple Sclerosis Patients. J Mashhad School Nurs Midw. 2009; 9(2):107-13. (Persian)
  20. Broach E, Groff D, Dattilo J, Yaff R, Gast D. The Effects of Aquatic Exercise on Adults with Multiple Sclerosis. Annual in Therapeutic Recreation. 1996; 7: 1-20
  21. Roehrs Tammy G, Karst Gregory M. Effects of an Aquatics Exercise Program on Quality of Life Measures for Individuals with Progressive Multiple Sclerosis. Journal of Neurological Physical Therapy. 2004; 28(2): 63-71.
  22. Schulz K.H, Gold S. M, Witte J, Bartsch K, Lang U. E, Hellweg R, Reer R, et al. Impact of Aerobic Training on Immune-Endocrine Parameters, Neurotrophic Factors, Quality of Life and Coordinative Function in Multiple Sclerosis. J Neurol Sci. 2004.
  23. Mokhtarian F, Shi Y, Shirazian D, Morgante L, Miller A, Grob D. Defective Production of Anti-Inflammatory Cytokine, TGF-Beta by T Cell Lines of Patients with Active Multiple Sclerosis. J Immunol. 1994; 152 (12) 6003-10.
  24. Pederson B, Hoffman k. Exercise and the Immune System: Regulation, Integration, and Adaptation. Physiol Rev. 2000; 80(3) 1055-81.
  25. Ozenci V, Kouwenhoven M, Huang YM, Kivisäkk P, Link H. "Multiple Sclerosis is Associated with an Imbalance between Tumour Necrosis Factor-Alpha (TNF-α) and IL-10 Secreting Blood Cells that is Corrected by Interferon-Beta (IFN-b) Treatment". Clin Exp Immunol. 2000; 120: 147-53.
  26. Heesen C, Gold S. M, Hartmann S, Mladek M, Reer R, Braumann K.M, Wiedemann K, et al. Endocrine and Cytokine Responses to Standardized Physical Stress in Multiple Sclerosis. Brain Behav Immun. 2003; 6: 473-81.
  27. Pedersen B.K, Wood A.J, NiemanC.D. Exercise –Induced Immune Changes-an Influence on Metabolism? TRENDS in Immunology. Trends Immunol. 2001; 22(9)473-74.
آمار
تعداد مشاهده مقاله: 4,317
تعداد دریافت فایل اصل مقاله: 1,986