سامانه مدیریت نشریات علمی دانشگاه علوم پزشکی مشهد

Sundaram, Venugopal, Khnna, David, P, Mohandass, R, Prabhu, Palanivel, Sathyaraj, Arya, Rekha, Chakravarty, Nilotpal, S, Antovaz, D, Palanivel. (1404). Adaptive Radiotherapy (ART) Using In Vivo Portal Dosimetry Constancy on Halcyon LINAC for Head and Neck Cancer VMAT. , 22(6), 430-438. doi: 10.22038/ijmp.2025.91205.2615
Venugopal Sundaram; David Khnna; Mohandass P; Prabhu R; Sathyaraj Palanivel; Rekha Arya; Nilotpal Chakravarty; Antovaz S; Palanivel D. "Adaptive Radiotherapy (ART) Using In Vivo Portal Dosimetry Constancy on Halcyon LINAC for Head and Neck Cancer VMAT". , 22, 6, 1404, 430-438. doi: 10.22038/ijmp.2025.91205.2615
Sundaram, Venugopal, Khnna, David, P, Mohandass, R, Prabhu, Palanivel, Sathyaraj, Arya, Rekha, Chakravarty, Nilotpal, S, Antovaz, D, Palanivel. (1404). 'Adaptive Radiotherapy (ART) Using In Vivo Portal Dosimetry Constancy on Halcyon LINAC for Head and Neck Cancer VMAT', , 22(6), pp. 430-438. doi: 10.22038/ijmp.2025.91205.2615
Sundaram, Venugopal, Khnna, David, P, Mohandass, R, Prabhu, Palanivel, Sathyaraj, Arya, Rekha, Chakravarty, Nilotpal, S, Antovaz, D, Palanivel. Adaptive Radiotherapy (ART) Using In Vivo Portal Dosimetry Constancy on Halcyon LINAC for Head and Neck Cancer VMAT. , 1404; 22(6): 430-438. doi: 10.22038/ijmp.2025.91205.2615

Adaptive Radiotherapy (ART) Using In Vivo Portal Dosimetry Constancy on Halcyon LINAC for Head and Neck Cancer VMAT

Iranian Journal of Medical Physics
دوره 22، شماره 6، بهمن و اسفند 2025، صفحه 430-438    اصل مقاله (1.48 M)
نوع مقاله: Original Paper
شناسه دیجیتال (DOI): 10.22038/ijmp.2025.91205.2615
نویسندگان
Venugopal Sundaram* 1؛ David Khnna2؛ Mohandass P3؛ Prabhu R4؛ Sathyaraj Palanivel5؛ Rekha Arya4؛ Nilotpal Chakravarty4؛ Antovaz S1؛ Palanivel D1
1Division of Physical Sciences, Karunya Institute of Technology and Sciences, Coimbatore, Tamilnadu, India.
2Division of Physical Sciences, Karunya Institute of Technology and Sciences, Karunya Nagar, Coimbatore, India- 641 114
3Department of Radiation Oncology, Fortis Hospital, Mohali, Punjab, India.
4Department of Radiation Oncology, Yashoda Super Specialty Hospital and Cancer Institute, Sanjay nagar, Ghaziabad, U.P. India.
5Department of Radiation Oncology, Kidwai memorial institute of oncology center, Bengaluru, India.
چکیده
Introduction: This study evaluated the potential of the Varian Halcyon LINAC and its associated Portal Dosimetry (PD) software, using in vivo megavoltage portal images, as a tool for in vivo portal dosimetry constancy (IVDc) in head and neck cancer (HNC) patients receiving volumetric modulated arc therapy (VMAT).
Material and Methods: A retrospective study included 100 HNC patients (mean age 58.4 ± 9.2 years; 72 males, 28 females) treated with three arc VMAT plans on the Halcyon LINAC. A prescription dose of 7000 cGy was delivered over 35 fractions to high risk volumes and 6300 cGy to intermediate risk volumes. Portal images from all fractions (3500) and arcs (10,500) were compared to first fraction baselines via gamma analysis with a 3%/2 mm criterion and 95% passing threshold. Phantom tests evaluated sensitivity to thickness changes.
Results: Gamma passing rates exhibited a steady decline over the treatment course (R²=0.9724), with an average 93.9 ± 3.6% passing rate, dropping below 90% after 25 fractions. Failures correlated with thickness variations exceeding 1 cm, which were detected with high accuracy during phantom tests. Pretreatment patient-specific QA yielded 100% pass rates.
Conclusion: This study demonstrates the potential of the Halcyon LINAC's integrated PD system and Varian PD software for IVDc in HNC patients treated with VMAT. The results confirm the feasibility of using in vivo MV portal images acquired on the Halcyon LINAC to assess dose consistency throughout treatment.
کلیدواژه‌ها
Head and Neck Neoplasms Radiotherapy Intensity؛ Modulated Radiotherapy Planning Computer؛ Assisted
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آمار
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