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Zakertavalaee, Fatemeh, Aelami, MohammadHasan, Khorashadizadeh, Mahdieh. (1404). A Case Presentation of Severe Plasmodium Falciparum Malaria in an 8-Year-Old Boy. , 13(4), 19430-19435. doi: 10.22038/jpp.2025.88192.5552
Fatemeh Zakertavalaee; MohammadHasan Aelami; Mahdieh Khorashadizadeh. "A Case Presentation of Severe Plasmodium Falciparum Malaria in an 8-Year-Old Boy". , 13, 4, 1404, 19430-19435. doi: 10.22038/jpp.2025.88192.5552
Zakertavalaee, Fatemeh, Aelami, MohammadHasan, Khorashadizadeh, Mahdieh. (1404). 'A Case Presentation of Severe Plasmodium Falciparum Malaria in an 8-Year-Old Boy', , 13(4), pp. 19430-19435. doi: 10.22038/jpp.2025.88192.5552
Zakertavalaee, Fatemeh, Aelami, MohammadHasan, Khorashadizadeh, Mahdieh. A Case Presentation of Severe Plasmodium Falciparum Malaria in an 8-Year-Old Boy. , 1404; 13(4): 19430-19435. doi: 10.22038/jpp.2025.88192.5552

A Case Presentation of Severe Plasmodium Falciparum Malaria in an 8-Year-Old Boy

Journal of Pediatric Perspectives
مقاله 6، دوره 13، شماره 4، تیر 2025، صفحه 19430-19435    اصل مقاله (532.66 K)
نوع مقاله: case report
شناسه دیجیتال (DOI): 10.22038/jpp.2025.88192.5552
نویسندگان
Fatemeh Zakertavalaee* 1؛ MohammadHasan Aelami2؛ Mahdieh Khorashadizadeh1
1Clinical Research Development Unit of Akbar Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
2Infection Control and Hand Hygiene Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
چکیده
Malaria is a life-threatening disease caused by Plasmodium species, with Plasmodium falciparum being the most virulent form. Cerebral malaria is a severe complication that can lead to various neurological manifestations. We report the case of an 8-year-old boy who presented with an unusual symptom of cerebral malaria—spastic gait. Diagnostic workup included a positive malaria rapid diagnostic test (RDT) and peripheral blood smear (PBS), confirming P.falciparum infection. Brain MRI revealed high signal intensities in the bilateral globus pallidus, consistent with cerebral involvement. The patient received intravenous Artesunate and a combination of antimalarial medications including Coartem, Primaquine, Quinine, and Clindamycin. He showed significant clinical improvement following treatment. This case highlights a rare neurological presentation of cerebral malaria and emphasizes the importance of early diagnosis and prompt treatment. Additionally, it underscores the value of neuroimaging, particularly MRI, in confirming cerebral involvement in atypical clinical presentations.
کلیدواژه‌ها
Malaria؛ Neuromalaria؛ Parasite infection؛ Plasmodium falciparum
مراجع
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