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RODRIGUEZ-MERCHAN, E. Carlos, De la Corte-Rodriguez, Hortensia. (1403). The Role of Intraarticular Injections of Hyaluronic Acid and Platelet Rich Plasma for the Treatment of Articular Pain in Knee Osteoarthritis. , 13(1), 54-61. doi: 10.22038/abjs.2024.78852.3621
E. Carlos RODRIGUEZ-MERCHAN; Hortensia De la Corte-Rodriguez. "The Role of Intraarticular Injections of Hyaluronic Acid and Platelet Rich Plasma for the Treatment of Articular Pain in Knee Osteoarthritis". , 13, 1, 1403, 54-61. doi: 10.22038/abjs.2024.78852.3621
RODRIGUEZ-MERCHAN, E. Carlos, De la Corte-Rodriguez, Hortensia. (1403). 'The Role of Intraarticular Injections of Hyaluronic Acid and Platelet Rich Plasma for the Treatment of Articular Pain in Knee Osteoarthritis', , 13(1), pp. 54-61. doi: 10.22038/abjs.2024.78852.3621
RODRIGUEZ-MERCHAN, E. Carlos, De la Corte-Rodriguez, Hortensia. The Role of Intraarticular Injections of Hyaluronic Acid and Platelet Rich Plasma for the Treatment of Articular Pain in Knee Osteoarthritis. , 1403; 13(1): 54-61. doi: 10.22038/abjs.2024.78852.3621

The Role of Intraarticular Injections of Hyaluronic Acid and Platelet Rich Plasma for the Treatment of Articular Pain in Knee Osteoarthritis

The Archives of Bone and Joint Surgery
مقاله 8، دوره 13، شماره 1، فروردین 2025، صفحه 54-61    اصل مقاله (696.98 K)
نوع مقاله: In Brief
شناسه دیجیتال (DOI): 10.22038/abjs.2024.78852.3621
نویسندگان
E. Carlos RODRIGUEZ-MERCHAN* 1؛ Hortensia De la Corte-Rodriguez2
1Department of Orthopedic Surgery, La Paz University Hospital-IdiPaz, Madrid, Spain
2Department of Physical Medicine and Rehabilitation, La Paz University Hospital-IdiPaz, Madrid, Spain
چکیده
The purpose of this in brief article was to determine the current role of intraarticular injections of hyaluronic acid (HA) and platelet-rich plasma (PRP) for the treatment of painful KOA. It has been reported that the average duration of effectiveness (pain relief) of one injection of extended-release HA is around one year. Kellgren-Lawrence grade (I-II versus III-IV), male gender, and older age are associated with a longer duration of effectiveness. Cartilage degeneration might be improved with a higher number of injections of HA. Intraarticular injections of HA alleviate pain, function, and diminish non-steroidal anti-inflammatory drugs (NSAIDs) consumption. In addition, several studies have indicated that the combination of HA and PRP is more effective than HA alone. Finally, other studies seemed to demonstrate that PRP was more effective than HA.
        Level of evidence: III
کلیدواژه‌ها
Efficacy؛ Hyaluronic acid؛ Intraarticular injections؛ Knee osteoarthritis؛ Platelet-rich plasma
مراجع
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