Impact of strawberry consumption on blood pressure in adults: GRADE-assessed systematic review and dose-response meta-analysis of data from randomized controlled trials | ||
| Avicenna Journal of Phytomedicine | ||
| دوره 15، شماره 5، آذر و دی 2025، صفحه 1408-1423 اصل مقاله (1.51 M) | ||
| نوع مقاله: Review Article | ||
| شناسه دیجیتال (DOI): 10.22038/ajp.2024.25222 | ||
| نویسندگان | ||
| Mostafa Shahraki Jazinaki1؛ Mohammad Safarian1؛ Mohammad Rashidmayvan2؛ Seyyed Mostafa Arabi3؛ Amirhossein Sahebkar* 4 | ||
| 1Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran | ||
| 2Department of Nutrition, Food Sciences and Clinical Biochemistry, School of Medicine, Social Determinants of Health Research Center, Gonabad University of Medical Science, Gonabad, Iran | ||
| 3Noncommunicable Diseases Research Center, Neyshabur University of Medical Sciences, Neyshabur, Iran | ||
| 4Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran | ||
| چکیده | ||
| Objective: This systematic review and meta-analysis aimed to assess the impact of strawberry (Fragaria x ananassa) consumption on systolic (SBP) and diastolic blood pressure (DBP). Materials and Methods: PubMed, Web of Science, Scopus, and Google Scholar were searched to find relevant randomized controlled trials (RCTs). Meta-analysis was carried out by using the random effect model, and the I2 index was used to assess heterogeneity among included trials. Results: Out of the 81 studies obtained, eight were eligible to be included in this review. The pooled effect size of 12 effect sizes indicated that strawberry consumption had no significant effect on SBP (WMD: 0.96 mmHg, 95% CI -0.26 to 2.20, p = 0.12), or DBP levels (WMD: -0.33 mmHg, 95% CI -1.31 to 0.65, p = 0.50). Subgroup analysis showed that consumption of freeze-dried strawberry powder at a dose of ≤ 25 g/day or strawberry intake in people under the age of 50 significantly increased SBP levels. Also, strawberry intake in individuals aged 50 or older led to a significant decrease in DBP levels. Conclusion: This review suggests that strawberry consumption may not be an effective strategy for hypertension management. However, more RCTs are needed to draw a definite conclusion. | ||
| کلیدواژهها | ||
| Strawberry؛ ragaria x ananassa؛ Systolic blood pressure؛ Diastolic blood pressure؛ Systematic review؛ Meta-analysis | ||
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