سامانه مدیریت نشریات علمی دانشگاه علوم پزشکی مشهد

Faramarzi Garmroudi, Raheleh, Rahimpour, Feisal, Aghdasi, Maryam, Emadzadeh, Maryam, Mottaghi Moghaddam shahri, Hassan, Moradian, Maryam, Saeidi, Reza, Heidari, Elahe. (1402). Myocardial Dysfunction Caused by Perinatal Asphyxia in Full-term Infants. , 12(Issue 3), 18628-18636. doi: 10.22038/ijp.2024.78701.5435
Raheleh Faramarzi Garmroudi; Feisal Rahimpour; Maryam Aghdasi; Maryam Emadzadeh; Hassan Mottaghi Moghaddam shahri; Maryam Moradian; Reza Saeidi; Elahe Heidari. "Myocardial Dysfunction Caused by Perinatal Asphyxia in Full-term Infants". , 12, Issue 3, 1402, 18628-18636. doi: 10.22038/ijp.2024.78701.5435
Faramarzi Garmroudi, Raheleh, Rahimpour, Feisal, Aghdasi, Maryam, Emadzadeh, Maryam, Mottaghi Moghaddam shahri, Hassan, Moradian, Maryam, Saeidi, Reza, Heidari, Elahe. (1402). 'Myocardial Dysfunction Caused by Perinatal Asphyxia in Full-term Infants', , 12(Issue 3), pp. 18628-18636. doi: 10.22038/ijp.2024.78701.5435
Faramarzi Garmroudi, Raheleh, Rahimpour, Feisal, Aghdasi, Maryam, Emadzadeh, Maryam, Mottaghi Moghaddam shahri, Hassan, Moradian, Maryam, Saeidi, Reza, Heidari, Elahe. Myocardial Dysfunction Caused by Perinatal Asphyxia in Full-term Infants. , 1402; 12(Issue 3): 18628-18636. doi: 10.22038/ijp.2024.78701.5435

Myocardial Dysfunction Caused by Perinatal Asphyxia in Full-term Infants

Journal of Pediatric Perspectives
دوره 12، Issue 3، خرداد 2024، صفحه 18628-18636    اصل مقاله (205.68 K)
نوع مقاله: original article
شناسه دیجیتال (DOI): 10.22038/ijp.2024.78701.5435
نویسندگان
Raheleh Faramarzi Garmroudi1؛ Feisal Rahimpour2؛ Maryam Aghdasi3؛ Maryam Emadzadeh4؛ Hassan Mottaghi Moghaddam shahri5؛ Maryam Moradian6؛ Reza Saeidi3، 7؛ Elahe Heidari* 3
1Assistant Professor of Neonatal-Perinatal Medicine, Department of Pediatrics, School of Medicine, Ghaem Hospital, Mashhad University of Medical Sciences.
2Pediatric Cardiologist, Fellow in Interventional Electrophysiology, Rajaie Cardiovascular Medical & Research Center, Iran University of Medical Sciences, Tehran, Iran.
3Department of Pediatrics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
4Clinical Research Development Unit, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.
5Associate Professor of Pediatric Cardiology, Department of Pediatrics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
6Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran.
7Neonatal Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
چکیده
Background: Perinatal asphyxia may cause multiple organ dysfunctions, including myocardial dysfunction. This study aimed to evaluate the prevalence and features of myocardial dysfunction in perinatal asphyxia.
Methods: This study was carried out on 31 neonates (≥37 weeks) with perinatal asphyxia who were admitted to the Neonatal Intensive Care Unit (NICU). The neonates underwent Electrocardiography (ECG) and Echocardiography (ECHO) in the first 72 hours of birth. Moreover, in the first 24 hours of birth, 1 cc of blood was taken from the patients for cardiac troponin I (cTnI) and creatine kinase-myocardial band (CK-MB) testing. Following that, venous blood gas was recorded one hour later.
Results: The mean 1- and 5-min Apgar scores were 4±1.76 and 6.8±1.6, respectively. The mean value of serum cTnI was 4±1.76, and mean level of CK-MB was obtained at 136.51±258.51. ECGs were of grade 1. Mitral valve E-wave/Early diastolic (51%), followed by Tricuspid Regurgitation Vena Contracta (48.4%) was found to be the commonest ECHO abnormality, and Mitral annular plane systolic excursion (96.8%) was the most normal ECHO parameter. Infants with ECG grade 1 changes had a lower 5-min Apgar score (P=0.014), and higher serum cTnI level (P=0.002). ECG changes were not significantly correlated with the mean of Apgar at 1 min, umbilical vein PH, and CK-MB.
Conclusion: ECG and ECHO changes, serum troponin I level, and 5-min Apgar score were found to be the predictors for myocardial dysfunction caused by asphyxia in newborn infants.
کلیدواژه‌ها
Birth asphyxia؛ Echocardiography؛ Electrocardiography؛ Myocardial changes؛ Neonate
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آمار
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