سامانه مدیریت نشریات علمی دانشگاه علوم پزشکی مشهد

Shajid, Syed, MANDAL, ABHIJIT, Mondal, Kalyan, Priean V, Gogul, Mukherjee, Bratindranath, Pandey, Praveen Chandra, Mishra, Himanshu, Mishra, Ritusha, Patel, Ganeshkumar, Mourya, Ankur, Aggarwal, Lalit, Choudhary, Sunil. (1403). Enhancing Fricke Xylenol Gel Dosimeter's Response to Radiation with Optimized Preparation Methods. , 22(1), 44-49. doi: 10.22038/ijmp.2024.74538.2320
Syed Mohamed Shajid; ABHIJIT MANDAL; Kalyan Mondal; Gogul Priean V; Bratindranath Mukherjee; Praveen Chandra Pandey; Himanshu Mishra; Ritusha Mishra; Ganeshkumar Ramesh Patel; Ankur Mourya; Lalit Mohan Aggarwal; Sunil Choudhary. "Enhancing Fricke Xylenol Gel Dosimeter's Response to Radiation with Optimized Preparation Methods". , 22, 1, 1403, 44-49. doi: 10.22038/ijmp.2024.74538.2320
Shajid, Syed, MANDAL, ABHIJIT, Mondal, Kalyan, Priean V, Gogul, Mukherjee, Bratindranath, Pandey, Praveen Chandra, Mishra, Himanshu, Mishra, Ritusha, Patel, Ganeshkumar, Mourya, Ankur, Aggarwal, Lalit, Choudhary, Sunil. (1403). 'Enhancing Fricke Xylenol Gel Dosimeter's Response to Radiation with Optimized Preparation Methods', , 22(1), pp. 44-49. doi: 10.22038/ijmp.2024.74538.2320
Shajid, Syed, MANDAL, ABHIJIT, Mondal, Kalyan, Priean V, Gogul, Mukherjee, Bratindranath, Pandey, Praveen Chandra, Mishra, Himanshu, Mishra, Ritusha, Patel, Ganeshkumar, Mourya, Ankur, Aggarwal, Lalit, Choudhary, Sunil. Enhancing Fricke Xylenol Gel Dosimeter's Response to Radiation with Optimized Preparation Methods. , 1403; 22(1): 44-49. doi: 10.22038/ijmp.2024.74538.2320

Enhancing Fricke Xylenol Gel Dosimeter's Response to Radiation with Optimized Preparation Methods

Iranian Journal of Medical Physics
دوره 22، شماره 1، فروردین و اردیبهشت 2025، صفحه 44-49    اصل مقاله (1.38 M)
نوع مقاله: Original Paper
شناسه دیجیتال (DOI): 10.22038/ijmp.2024.74538.2320
نویسندگان
Syed Mohamed Shajid1؛ ABHIJIT MANDAL* 2؛ Kalyan Mondal3؛ Gogul Priean V4؛ Bratindranath Mukherjee5؛ Praveen Chandra Pandey6؛ Himanshu Mishra7؛ Ritusha Mishra8؛ Ganeshkumar Ramesh Patel9؛ Ankur Mourya10؛ Lalit Mohan Aggarwal11؛ Sunil Choudhary7
1Radiotherapy and Radiation Medicine, Institute of Medical Sciences, Banaras Hindu University.
2BANARAS HINDU UNIVERSITY
3Department of Radiotherapy, North Bengal Medical College, Darjeeling, India-734012
4Radiotherapy and Radiation Medicine, Institute of Medical Sciences, Banaras Hindu University
5Department of Metallurgical Engineering, Institute of Technology, Banaras Hindu University.
6Department of Physics, Institute of Technology, Banaras Hindu University
7Department of Radiotherapy and Radiation Medicine Institute of Medical Sciences Banaras Hindu University VARANASI, Uttar Pradesh, INDIA.
8RTRM Department, Institute of Medical Sciences, BHU, Varanasi-221005
9RTRM Department, Institute of Medical Sciences, Banaras Hindu University, Varanasi-221005, INDIA
10Department of Radiotherapy and Radiation Medicine, Institute of Medical Sciences, Banaras Hindu University.
11Institute of Medical Science (BHU)Varanasi, UP, India
چکیده
Introduction: The fundamental principle of the Fricke gel dosimeter involves the oxidation of ferric ions upon exposure to radiation. However, a significant limitation of this dosimeter is the post-irradiation diffusion of ferric ions, which can result in the degradation of spatial dose information.
Material and Methods: Gels were prepared using 300 bloom gelatin, deionized water, sulfuric acid, ferrous ammonium sulfate, and xylenol orange dye (Sigma-Aldrich). The solution was then poured into 10 ml plastic cuvettes.. The gel samples were refrigerated at various temperatures for 1 to 10 days and irradiated within a water bath environment utilizing a telecobalt unit (Phoenix, Theratronics) employing parallel opposed beams. Spectrophotometric analysis at  a wavelength of 585 nm was used to measured optical density changes with dose.. This procedure was repeated across gel formulations prepared under differing pH conditions.
Results: The gel's optimum pH value, which was stored for 10 days at 5° C, showed a linear response up to 10 Gy, although the storage time was longer than that of the gels with low (0.3) and high pH (1.3). The auto oxidation rate was determined and found to be less for non-irradiated gel batches stored at 5° C in relation to the gel samples at room temperature and freezing temperature.
Conclusion: The dose response of the dosimeter is highly dependent on its pH, composition, alkaline residuals, and pre-irradiation storing conditions.. We observed the optimum pH is 1, at which the dosimeter shows a maximum response. Storing gel samples at 5°C notably reduces the Fe2+ to Fe3+ auto-oxidation rate.
کلیدواژه‌ها
Cancer؛ Radiation Therapy؛ Fricke Solutions؛ Spectrophotometry
مراجع
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