سامانه مدیریت نشریات علمی دانشگاه علوم پزشکی مشهد

Ardalan Khales, Sahar, Vakili, Mohammad Ali, Golalipour, Mohammad Jafar. (1403). Congenital Malformations of the Digestive System in Northern Iran (2018-19). , 15(2), 49-52. doi: 10.22038/ijn.2024.74387.2442
Sahar Ardalan Khales; Mohammad Ali Vakili; Mohammad Jafar Golalipour. "Congenital Malformations of the Digestive System in Northern Iran (2018-19)". , 15, 2, 1403, 49-52. doi: 10.22038/ijn.2024.74387.2442
Ardalan Khales, Sahar, Vakili, Mohammad Ali, Golalipour, Mohammad Jafar. (1403). 'Congenital Malformations of the Digestive System in Northern Iran (2018-19)', , 15(2), pp. 49-52. doi: 10.22038/ijn.2024.74387.2442
Ardalan Khales, Sahar, Vakili, Mohammad Ali, Golalipour, Mohammad Jafar. Congenital Malformations of the Digestive System in Northern Iran (2018-19). , 1403; 15(2): 49-52. doi: 10.22038/ijn.2024.74387.2442

Congenital Malformations of the Digestive System in Northern Iran (2018-19)

Iranian Journal of Neonatology
دوره 15، شماره 2، تیر 2024، صفحه 49-52    اصل مقاله (347.43 K)
نوع مقاله: Original Article
شناسه دیجیتال (DOI): 10.22038/ijn.2024.74387.2442
نویسندگان
Sahar Ardalan Khales1؛ Mohammad Ali Vakili2؛ Mohammad Jafar Golalipour* 3
11.Golestan Research Center of Gastroenterology and Hepatology, Golestan University of Medical Sciences, Gorgan, Iran. 2.Gorgan Congenital Malformations Research Center, Golestan University of Medical Sciences, Gorgan, Iran.
2Health Management and Social Development Research Center, Department of Biostatistics and Epidemiology, Golestan University of Medical Sciences, Gorgan, Iran
3Gorgan Congenital Malformations Research Center, Golestan University of Medical Sciences, Gorgan, Iran
چکیده
Background: Congenital malformations of the digestive system (CMDS) are one of the major causes of newborn mortality, particularly in developing countries. This study was conducted to evaluate the prevalence, pattern, gender distribution of CMDS as well as ethnicity status among newborns in Golestan Province, northern Iran.
Methods: This descriptive and analytical study was conducted on 36,156 live births to identify all newborns with CMDS, born between March 2018 and March 2019 in Golestan Province, north of Iran. The type of CMDS according to the International Classification of Diseases (ICD-10), the gender and ethnicity status of the newborns were recorded. The prevalence rate was estimated and compared using the exact Poisson method and odds ratio with a 95% confidence interval. Data were analyzed using STATA 14.0 software.
Results: The prevalence rate of CMDS in newborns was 2.13 per 1000 live births. The risk of CMDS was significantly higher in males compared to females (OR=1.78, 95% CI: 1.12-2.85). The most common anomaly was Ankyloglossia (19.28%). The prevalence rate of CMDS among native Fars, Turkmen and Sistani ethnic groups was 2.15 [95% CI: 1.50-2.99], 3.05 [95% CI: 2.06-4.35] and 1.48 [95% CI: 0.64-2.91] per 1000 live births, respectively.
Conclusion: Due to the prevalence rate of CMDS and ethnic diversity in this region, effective prevention planning, early diagnosis and thorough screening are particularly important, especially in high-risk groups.
 
 
کلیدواژه‌ها
Digestive system malformations؛ Ethnicity؛ Iran؛ Prevalence 
مراجع
  1. World Health Organization. Congenital anomalies. Available from: http://www.who.int/mediacentre/ factsheets/fs370/en/.
  2. Christianson A, Howson CP, Modell B. March of Dimes, Global Report on Birth Defect, The hidden toll of dying and disabled children, 2005. Available from: http://www.marchofdimes.org/global-report-on-birth-defects-the-hiddentoll-of-dying-and-disabled-children executive-summary.pdf
  3. Golalipour MJ, Vakili MA. Gross congenital malformations in 10000 births (Gorgan Dezyani Hospital 1997-99). J Gorgan Univ Med Sci. 2002;4(2):42-47.
  4. Shawky RM, Sadik DI. Congenital malformations prevalent among Egyptian children and associated risk factors. Egypt J Med Hum Genet. 2011;12(1):69-78.
  5. Birch MR, Grayson N, Sullivan EA. Recommendations for development of a new Australian birth anomalies system: A review of the congenital malformations and birth defects data collection. AIHW National Perinatal Statistics Unit. 2004.
  6. Harris J, Kallen B, Robert E. Descriptive epidemiology of alimentary tract atresia. Teratology. 1995;52(1):15-29.
  7. Rankin J, Dillon E, Wright C. Congenital anterior abdominal wall defects in the north of England, 1986-1996: occurrence and outcome. Prenat Diagn. 1999;19(7):662-668.
  8. Spitz L, Kiely EM, Morecroft JA, Drake DP. Oesophageal atresia: at-risk groups for the 1990s. J Pediatr Surg. 1994;29(6):723-725.
  9. Garne E, Rasmussen L, Husby S. Gastrointestinal malformations in Funen county, Denmark-epidemiology, associated malformations, surgery and mortality. Eur J Pediatr Surg. 2002;12(2):101-106.
  10. Golalipour MJ, Mobasheri E, Hoseinpour KR, Keshtkar AA. Gastrointestinal malformations in Gorgan, North of Iran: epidemiology and associated malformations. Pediatr Surg Int. 2007;23(1):75-79.
  11. Song F, Chen J, Cai W. The prevalence of digestive tract defects in East China: A population-based study. Sci J Pediatrics Child Care. 2022;1:01-8.
  12. Abdu H, Seyoum G. Prevalence and outcomes of birth defects in newborns of South Wollo and Oromia zones of Amhara regional state: a retrospective study. Ethiop J health Dev. 2019;33(3).
  13. Kumar A, Singh K. Major congenital malformations of the gastrointestinal tract among the newborns in one of the English Caribbean Countries, 1993-2012. J Clin Neonatol. 2014;3(4):205-210.
  14. Singh K, Krishnamurthy K, Greaves C, Kandamaran L, Nielsen AL, Kumar A. Major congenital malformations in Barbados: the prevalence, the pattern, and the resulting morbidity and mortality. ISRN Obstet Gynecol. 2014;2014:651783.
  15. Tayebi N, Yazdani K, Naghshin N. The prevalence of congenital malformations and its correlation with consanguineous marriages. Oman Med J. 2010; 25(1):37-40. 
  16. Ahmadzadeh A, Safikhani Z, Abdulahi M, Ahmadzadeh A. Congenital malformations among live births at Arvand Hospital, Ahwaz, Iran-A prospective study. Pak J Med Sci. 2008;24(1):33-37.
  17. Abdi-Rad I, Khoshkalam M, Farrokh-Islamlou HR. The prevalence at birth of overt congenital anomalies in Urmia, Northwestern Iran. Arch Iran Med. 2008;11(2):148-151.
  18. Dastgiri S, Stone DH, Le-Ha C, Gilmour WH. Prevalence and secular trend of congenital anomalies in Glasgow, UK. Arch Dis Child. 2002;86(4):257-263.
  19. Yang M, Zhang S, Du Y. Epidemiology characteristics of birth defects in Shenzhen city during 2003 to 2009, China. J Matern Fetal Neonatal Med. 2015;28(7):799-803.
  20. Sheridan E, Wright J, Small N, Corry PC, Oddie S, Whibley C, et al. Risk factors for congenital anomaly in a multiethnic birth cohort: an analysis of the Born in Bradford study. Lancet. 2013;382(9901):1350-1359.
  21. Forrester MB, Merz RD. Descriptive epidemiology of anal atresia in Hawaii, 1986-1999. Teratology. 2002;66 Suppl 1:S12-6.
آمار
تعداد مشاهده مقاله: 267
تعداد دریافت فایل اصل مقاله: 230