سامانه مدیریت نشریات علمی دانشگاه علوم پزشکی مشهد

شفائی, اعظم, شمسیان, دکتر علی اکبر, تارا, دکتر فاطمه, شاهی, دکتر مریم. (1403). ویروس پاپیلومای انسانی و بارداری: یک مطالعه مروری نقلی. , 27(2), 60-70. doi: 10.22038/ijogi.2024.70140.5581
اعظم شفائی; دکتر علی اکبر شمسیان; دکتر فاطمه تارا; دکتر مریم شاهی. "ویروس پاپیلومای انسانی و بارداری: یک مطالعه مروری نقلی". , 27, 2, 1403, 60-70. doi: 10.22038/ijogi.2024.70140.5581
شفائی, اعظم, شمسیان, دکتر علی اکبر, تارا, دکتر فاطمه, شاهی, دکتر مریم. (1403). 'ویروس پاپیلومای انسانی و بارداری: یک مطالعه مروری نقلی', , 27(2), pp. 60-70. doi: 10.22038/ijogi.2024.70140.5581
شفائی, اعظم, شمسیان, دکتر علی اکبر, تارا, دکتر فاطمه, شاهی, دکتر مریم. ویروس پاپیلومای انسانی و بارداری: یک مطالعه مروری نقلی. , 1403; 27(2): 60-70. doi: 10.22038/ijogi.2024.70140.5581

ویروس پاپیلومای انسانی و بارداری: یک مطالعه مروری نقلی

مجله زنان، مامایی و نازایی ایران
دوره 27، شماره 2، اردیبهشت 1403، صفحه 60-70    اصل مقاله (742.89 K)
نوع مقاله: مروری
شناسه دیجیتال (DOI): 10.22038/ijogi.2024.70140.5581
نویسندگان
اعظم شفائی1؛ دکتر علی اکبر شمسیان2؛ دکتر فاطمه تارا3؛ دکتر مریم شاهی* 4
1کارشناس ارشد بیوشیمی بالینی، مرکز تحقیقات عفونت‌های منتقله از خون، سازمان جهاد دانشگاهی خراسان رضوی، مشهد، ایران.
2استاد گروه انگل‌شناسی و قارچ‌شناسی، دانشکده پزشکی، دانشگاه علوم پزشکی مشهد، مشهد، ایران. سازمان جهاد دانشگاهی خراسان رضوی، مشهد، ایران.
3استاد گروه زنان و مامایی، هسته تحقیقاتی حمایت از خانواده و جوانی جمعیت، دانشکده پزشکی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.
4دکترای تخصصی پزشکی مولکولی، مرکز تحقیقات عفونت‌های منتقله از خون، جهاد دانشگاهی خراسان رضوی، مشهد، ایران.
چکیده
مقدمه: ویروس پاپیلومای انسانی (HPV) شایع‌ترین عفونت منتقله از راه جنسی است. ویروس HPV در صورت پایداری در بدن، عامل ایجاد چندین سرطان در ناحیه آنوژنیتال و اوروفارنکس است. ابتلاء به ویروس HPV در دوران بارداری ممکن است با پیامدهای نامطلوبی همچون زایمان زودرس و سقط جنین همراه باشد؛ مطالعه حاضر با هدف بررسی ارتباط عفونت HPV با پیامدهای نامطلوب بارداری در مطالعات مختلف انجام شد.
روش‌کار: در این مطالعه مروری نقلی، برای یافتن مقالات مرتبط، پایگاه‌های PubMed و Google Scholar با استفاده از کلمات کلیدی HPV، Papillomavirus، HPV in Pregnancy، HPV Transmission و Adverse outcomes از سال 2000 تا 2022 جستجو شدند. بدین‌منظور مقالات پژوهشی اصیل، کارآزمایی بالینی، مروری و گزارش موردی مرتبط با موضوع مورد بررسی وارد مطالعه شده و مطالعات غیرمرتبط حذف شدند. فرآیند گزینش مقالات به‌ترتیب با مطالعه عنوان، چکیده و محتوا انجام شد. زبان پذیرش مقالات انگلیسی بود.
یافته ­ها: نتایج مطالعات نشان داده‌اند که خطر ابتلاء به عفونت HPV در زنان باردار نسبت به زنان غیرباردار بالاتر است. همچنین خطر زایمان زودرس و پارگی زودرس کیسه آب در زنان باردار HPV مثبت بیشتر از زنان HPV منفی گزارش شده ­است. برخی مطالعات به ارتباط HPV و مرگ خودبه‌خودی جنین نیز اشاره نموده‌اند.
نتیجه ­گیری: با توجه به عوارض متعدد ابتلاء به عفونت HPV در زنان باردار، بهتر است قبل از بارداری از عدم ابتلاء به این ویروس، اطمینان حاصل شود.
کلیدواژه‌ها
بارداری؛ سرطان؛ واکسیناسیون؛ ویروس پاپیلومای انسانی (HPV)
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