سامانه مدیریت نشریات علمی دانشگاه علوم پزشکی مشهد

Peivandi, Sepideh, Heydari-latibari, Sahar, Ghasemzadeh, Fatemeh, Zamaniyan, Marzieh, Bahar, Adele, Majidi, Hadi, Maleki, Behnam. (1402). Metabolic and endocrine changes induced by cinnamon in women with polycystic ovarian syndrome: A pilot study. , 14(2), 242-251. doi: 10.22038/ajp.2023.23357
Sepideh Peivandi; Sahar Heydari-latibari; Fatemeh Ghasemzadeh; Marzieh Zamaniyan; Adele Bahar; Hadi Majidi; Behnam Maleki. "Metabolic and endocrine changes induced by cinnamon in women with polycystic ovarian syndrome: A pilot study". , 14, 2, 1402, 242-251. doi: 10.22038/ajp.2023.23357
Peivandi, Sepideh, Heydari-latibari, Sahar, Ghasemzadeh, Fatemeh, Zamaniyan, Marzieh, Bahar, Adele, Majidi, Hadi, Maleki, Behnam. (1402). 'Metabolic and endocrine changes induced by cinnamon in women with polycystic ovarian syndrome: A pilot study', , 14(2), pp. 242-251. doi: 10.22038/ajp.2023.23357
Peivandi, Sepideh, Heydari-latibari, Sahar, Ghasemzadeh, Fatemeh, Zamaniyan, Marzieh, Bahar, Adele, Majidi, Hadi, Maleki, Behnam. Metabolic and endocrine changes induced by cinnamon in women with polycystic ovarian syndrome: A pilot study. , 1402; 14(2): 242-251. doi: 10.22038/ajp.2023.23357

Metabolic and endocrine changes induced by cinnamon in women with polycystic ovarian syndrome: A pilot study

Avicenna Journal of Phytomedicine
دوره 14، شماره 2، خرداد و تیر 2024، صفحه 242-251    اصل مقاله (783.48 K)
نوع مقاله: Original Research Article
شناسه دیجیتال (DOI): 10.22038/ajp.2023.23357
نویسندگان
Sepideh Peivandi* 1؛ Sahar Heydari-latibari2؛ Fatemeh Ghasemzadeh2؛ Marzieh Zamaniyan3؛ Adele Bahar4؛ Hadi Majidi5؛ Behnam Maleki6
1Sexual and Reproductive Health Research Center, Department of OB/GYN, IVF Ward, Sari Imam Khomeini Hospital, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
2Department of OB/GYN, IVF Ward, Sari Imam Khomeini Hospital, Mazandaran University of Medical Sciences, Sari, Iran
3Diabetic Research Center, Department of OB/GYN, IVF Ward, Sari Imam Khomeini Hospital, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
4Department of Endocrinology, Diabetic Research Center, Sari Imam Khomeini Hospital, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
5Department of Radiology, Sari Imam Khomeini Hospital, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
6IVF Ward, Sari Imam Khomeini Hospital, Mazandaran University of Medical Sciences, Sari, Iran
چکیده
Objective: Most polycystic ovary syndrome (PCOS) patients have metabolic abnormalities in which insulin resistance (IR) plays a pivotal role. Cinnamon is a herbal medicine with insulinotropic properties. This pilot study aimed to evaluate the effects of cinnamon on ovarian volume, androgenic profile, and metabolic and anthropometric parameters in women with PCOS.
Materials and Methods: A single-center, double-blind, randomized, placebo-controlled trial was carried out on 39 overweight / obese women with PCOS. For six months, subjects in the cinnamon (500 mg) (n=19) and placebo (n=20) groups were given three capsules daily. Before and after the intervention, the variables were assessed. The data was analyzed using the GraphPad Prism software.
Results: After the intervention, the two intervention and control groups had significant differences in abdominal subcutaneous fat and ovarian volume, but they did not differ significantly in terms of body mass index (BMI). Also, after the intervention, no significant difference was observed between the two groups in terms of lipid profile and the concentration of androgenic biomarkers of insulin resistance.
Conclusion: Cinnamon supplementation improves ovarian volume and subcutaneous abdominal fat but has no effect on anthropometric parameters, lipid profile, insulin resistance, or androgen hormones.
کلیدواژه‌ها
Cinnamon؛ Polycystic ovarian syndrome؛ Menstruation؛ Insulin resistance؛ Lipids؛ Abdominal fat
آمار
تعداد مشاهده مقاله: 31,339
تعداد دریافت فایل اصل مقاله: 62,216