سامانه مدیریت نشریات علمی دانشگاه علوم پزشکی مشهد

Salmani-Javan, Elnaz, Farhoudi Sefidan Jadid, Mahdi, Zarghami, Nosratollah. (1402). Recent advances in molecular targeted therapy of lung cancer: Possible application in translation medicine. , 27(2), 122-133. doi: 10.22038/ijbms.2023.72407.15749
Elnaz Salmani-Javan; Mahdi Farhoudi Sefidan Jadid; Nosratollah Zarghami. "Recent advances in molecular targeted therapy of lung cancer: Possible application in translation medicine". , 27, 2, 1402, 122-133. doi: 10.22038/ijbms.2023.72407.15749
Salmani-Javan, Elnaz, Farhoudi Sefidan Jadid, Mahdi, Zarghami, Nosratollah. (1402). 'Recent advances in molecular targeted therapy of lung cancer: Possible application in translation medicine', , 27(2), pp. 122-133. doi: 10.22038/ijbms.2023.72407.15749
Salmani-Javan, Elnaz, Farhoudi Sefidan Jadid, Mahdi, Zarghami, Nosratollah. Recent advances in molecular targeted therapy of lung cancer: Possible application in translation medicine. , 1402; 27(2): 122-133. doi: 10.22038/ijbms.2023.72407.15749

Recent advances in molecular targeted therapy of lung cancer: Possible application in translation medicine

Iranian Journal of Basic Medical Sciences
مقاله 1، دوره 27، شماره 2، اردیبهشت 2024، صفحه 122-133    اصل مقاله (1.4 M)
نوع مقاله: Review Article
شناسه دیجیتال (DOI): 10.22038/ijbms.2023.72407.15749
نویسندگان
Elnaz Salmani-Javan1؛ Mahdi Farhoudi Sefidan Jadid1؛ Nosratollah Zarghami* 2
1Department of Clinical Biochemistry and Laboratory Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
2Department of Medical Biochemistry, Faculty of Medicine, Istanbul Aydin University, Istanbul, Turkey
چکیده
Lung cancer is one of the leading causes of death among all cancer deaths. This cancer is classified into two different histological subtypes: non-small cell lung cancer (NSCLC), which is the most common subtype, and small cell lung cancer (SCLC), which is the most aggressive subtype. Understanding the molecular characteristics of lung cancer has expanded our knowledge of the cellular origins and molecular pathways affected by each of these subtypes and has contributed to the development of new therapies. Traditional treatments for lung cancer include surgery, chemotherapy, and radiotherapy. Advances in understanding the nature and specificity of lung cancer have led to the development of immunotherapy, which is the newest and most specialized treatment in the treatment of lung cancer. Each of these treatments has advantages and disadvantages and causes side effects. Today, combination therapy for lung cancer reduces side effects and increases the speed of recovery. Despite the significant progress that has been made in the treatment of lung cancer in the last decade, further research into new drugs and combination therapies is needed to extend the clinical benefits and improve outcomes in lung cancer. In this review article, we discussed common lung cancer treatments and their combinations from the most advanced to the newest.
کلیدواژه‌ها
Combination therapy؛ Immunotherapy؛ Lung cancer؛ Molecular targeted therapy؛ Translational medicine
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