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Aguiar, Cristina, Pina, Paulo, Medeiros, Nuno, Teixeira, Monica, Ribeiro, Leandro, Oliveira, Pedro. (1402). Necrosis of the Tongue as a Late Complication of Radiotherapy. , 35(5), 285-288. doi: 10.22038/ijorl.2023.67124.3305
Cristina Aguiar; Paulo Pina; Nuno Medeiros; Monica Teixeira; Leandro Ribeiro; Pedro Oliveira. "Necrosis of the Tongue as a Late Complication of Radiotherapy". , 35, 5, 1402, 285-288. doi: 10.22038/ijorl.2023.67124.3305
Aguiar, Cristina, Pina, Paulo, Medeiros, Nuno, Teixeira, Monica, Ribeiro, Leandro, Oliveira, Pedro. (1402). 'Necrosis of the Tongue as a Late Complication of Radiotherapy', , 35(5), pp. 285-288. doi: 10.22038/ijorl.2023.67124.3305
Aguiar, Cristina, Pina, Paulo, Medeiros, Nuno, Teixeira, Monica, Ribeiro, Leandro, Oliveira, Pedro. Necrosis of the Tongue as a Late Complication of Radiotherapy. , 1402; 35(5): 285-288. doi: 10.22038/ijorl.2023.67124.3305

Necrosis of the Tongue as a Late Complication of Radiotherapy

Iranian Journal of Otorhinolaryngology
مقاله 7، دوره 35، شماره 5 - شماره پیاپی 130، آذر و دی 2023، صفحه 285-288    اصل مقاله (608.38 K)
نوع مقاله: Case Report
شناسه دیجیتال (DOI): 10.22038/ijorl.2023.67124.3305
نویسندگان
Cristina Aguiar* 1؛ Paulo Pina2؛ Nuno Medeiros3؛ Monica Teixeira1؛ Leandro Ribeiro1؛ Pedro Oliveira1
1Department of Otorhinolaryngology, Centro Hospitalar Vila Nova de Gaia/Espinho, Porto, Portugal
2Department of Otorhinolaryngology Department, Centro Hospitalar de Vila Nova de Gaia/Espinho, Porto, Portugal
3Department of Otorhinolaryngology, Centro Hospitalar Vila Nova de Gaia / Espinho, Porto, Portugal
چکیده
Introduction:
Irradiation to treat head and neck cancer, causing chronic tissue damage, is associated with the development of vascular disease. Interest has risen over the effects of radiotherapy on major vessels, due to its high morbidity and mortality rate. However, small-vessel disease has been poorly studied and described.
Case Report
We present a case of a patient with bilateral necrosis of the anterior third of the tongue, occurring 3 years after chemoradiotherapy treatment for squamous cell carcinoma of the floor of the mouth. Contrast-enhanced CT scan showed multiple areas of stenosis concerning both external carotid arteries and their branches, and total opacification of lingual arteries. Conservative management was performed, with auto-amputation on the fifth day, which allowed healing by secondary intention.
Conclusions:
Necrosis of the tongue appears as a rare late complication of radiotherapy, possibly due to its acceleration effect on the atherosclerosis process. Following small-vessel disease, one can assume a higher potential risk of major-vessel disease, highlighting the importance of a routine assessment and prophylaxis of thrombotic events.
کلیدواژه‌ها
Late complications؛ Radiotherapy؛ Small-vessel disease؛ Tongue necrosis
مراجع
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آمار
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