سامانه مدیریت نشریات علمی دانشگاه علوم پزشکی مشهد

Bahrami-Taghanaki, Hamid Reza, Hoseinzadeh, Hamidreza, Hamedi, Shokouhsadat, Jafari Nejad-Bajestani, Majid, Esmaeilzadeh, Nayereh, Abdollahzadeh, Hasan, Hoseini-asil, Seyedehmasoume, Haghighi, Gholamreza, Bojdi, Amin. (1402). The effect of Phytopaj )Ferula assa-foetida L. oleo gum resin and tragacanth( in patients with COVID-19: A randomized clinical trial. , 14(2), 152-165. doi: 10.22038/ajp.2023.22800
Hamid Reza Bahrami-Taghanaki; Hamidreza Hoseinzadeh; Shokouhsadat Hamedi; Majid Jafari Nejad-Bajestani; Nayereh Esmaeilzadeh; Hasan Abdollahzadeh; Seyedehmasoume Hoseini-asil; Gholamreza Haghighi; Amin Bojdi. "The effect of Phytopaj )Ferula assa-foetida L. oleo gum resin and tragacanth( in patients with COVID-19: A randomized clinical trial". , 14, 2, 1402, 152-165. doi: 10.22038/ajp.2023.22800
Bahrami-Taghanaki, Hamid Reza, Hoseinzadeh, Hamidreza, Hamedi, Shokouhsadat, Jafari Nejad-Bajestani, Majid, Esmaeilzadeh, Nayereh, Abdollahzadeh, Hasan, Hoseini-asil, Seyedehmasoume, Haghighi, Gholamreza, Bojdi, Amin. (1402). 'The effect of Phytopaj )Ferula assa-foetida L. oleo gum resin and tragacanth( in patients with COVID-19: A randomized clinical trial', , 14(2), pp. 152-165. doi: 10.22038/ajp.2023.22800
Bahrami-Taghanaki, Hamid Reza, Hoseinzadeh, Hamidreza, Hamedi, Shokouhsadat, Jafari Nejad-Bajestani, Majid, Esmaeilzadeh, Nayereh, Abdollahzadeh, Hasan, Hoseini-asil, Seyedehmasoume, Haghighi, Gholamreza, Bojdi, Amin. The effect of Phytopaj )Ferula assa-foetida L. oleo gum resin and tragacanth( in patients with COVID-19: A randomized clinical trial. , 1402; 14(2): 152-165. doi: 10.22038/ajp.2023.22800

The effect of Phytopaj )Ferula assa-foetida L. oleo gum resin and tragacanth( in patients with COVID-19: A randomized clinical trial

Avicenna Journal of Phytomedicine
دوره 14، شماره 2، خرداد و تیر 2024، صفحه 152-165    اصل مقاله (979.04 K)
نوع مقاله: Short communication
شناسه دیجیتال (DOI): 10.22038/ajp.2023.22800
نویسندگان
Hamid Reza Bahrami-Taghanaki1؛ Hamidreza Hoseinzadeh2؛ Shokouhsadat Hamedi3؛ Majid Jafari Nejad-Bajestani2؛ Nayereh Esmaeilzadeh* 4؛ Hasan Abdollahzadeh2؛ Seyedehmasoume Hoseini-asil5؛ Gholamreza Haghighi6؛ Amin Bojdi5
1Department of Complementary and Chinese Medicine, Faculty of Persian and Complementary Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
2Department of Persian Medicine, School of Persian and Complementary Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
3Department of Clinical Persian Pharmacy, School of Persian and Complementary Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
4Department of Epidemiology, School of Health, Mashhad University of Medical Sciences, Mashhad, Iran
5Department of Infectious Diseases and Tropical Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
6Department of Traditional Medicine, School of Medicine, Zabol University of Medical Sciences, Zabol, Iran
چکیده
Objective: Exogenous hydrogen sulfide (H2S) has a positive effect on respiratory diseases. Oleo-gum of Ferula assa-foetida contains this compound. This study assessed the effects of Ferula assa-foetida L. oleo gum resin and tragacanth (Phytopaj) on patients with COVID-19. 
Materials and Methods: A randomized, single-blinded, controlled trial (RCT) phase 2 was conducted in Mashhad on hospitalized COVID-19 patients. In this RCT, 122 patients were randomly assigned to either receive a 14-day oral phytopaj plus ordinary treatment or ordinary treatment only. Changes in peripheral blood lymphocyte count (LC) and blood oxygen saturation (PO2) were the endpoints. Results: Mean±SD of PO2 in Phytopaj comparison ordinary treatment before intervention was 91.86±4.62 and 91.41±9.18, after the intervention it was 93.22±4.26 and 91.91±5.92 mmHg; before intervention, mean±SD of peripheral blood lymphocyte count was 1015.90±500.55, and 1104.28±543.61, and after intervention, it was 1652.27±921.38 and 1326.12±719.28/μL respectively. Participants' age, comorbidity, gender, and stage of
Conclusion: Phyopaj is most useful in moderate stages of Covid19, and it is not recommended for elderly patients and patients with comorbidity until more insight is gained.
کلیدواژه‌ها
COVID-19؛ Herbal medicine؛ Integrative medicine؛ Persian medicine؛ Randomized controlled trial؛ Ferula foetida؛ H2S donors
آمار
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