Limb Saving with a Combination of Allogenic Platelets Rich Plasma, Fibrin Glue, and Collagen Matrix in an Open Fracture of the Tibia: A Case Report | ||
| The Archives of Bone and Joint Surgery | ||
| مقاله 8، دوره 11، شماره 8، آبان 2023، صفحه 535-538 اصل مقاله (878.56 K) | ||
| نوع مقاله: CASE REPORT | ||
| شناسه دیجیتال (DOI): 10.22038/abjs.2023.69184.3261 | ||
| نویسندگان | ||
| Hamid Reza Rahimi1؛ Elaheh Emadi2؛ Daryoush Hamidi Alamdari* 3 | ||
| 1Department of Medical Genetics and Molecular Medicine, Mashhad University of Medical Sciences, Mashhad, Iran | ||
| 2Vascular and Endovascular Surgery Research Center, Mashhad University of Medical Sciences, Mashhad, Iran | ||
| 3Surgical Oncology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran | ||
| چکیده | ||
| Tibia open fractures and lower limb soft tissue injuries are undesired conditions for orthopedic and general surgeons, and there is no ideal procedure for treating recalcitrant ulcers or severe traumatic ulcers. Recently, several novel approaches have been proposed, such as bone marrow stem cells, platelets, fibrin glue, and collagen matrix. The current study was conducted to evaluate the effectiveness of combining platelets, fibrin glue, and a collagen matrix for treating a serious limb - threatening wound in a 33-year-old male with a right lower limb injury. After treatment, the wound was fully closed, tissue granulation was grown, skin grafting was done, and the right leg was saved. In conclusion, the combination of the mentioned components can be utilized to synergistically enhance wound healing and preserve the limb. Level of evidence: V | ||
| کلیدواژهها | ||
| Collagen matrix؛ Fibrin glue؛ Limb-threatening wound؛ Platelets-rich plasma | ||
| مراجع | ||
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1. Fairhurst M. The function of below knee amputees versus the patient with salvaged grade-III tibial fracture. Clin Orthop. 1994 ;( 301):227-32. 2. Brod M. Quality of life issues in patients with diabetes and lower extremity ulcers: patients and care givers. Qual Life Res. 1998; 7(4):365-72. doi: 10.1023/a:1024994232353. 3. Singh N, Armstrong DG, Lipsky BA. Preventing foot ulcers in patients with diabetes. JAMA. 2005; 293(2):217-28. doi: 10.1001/jama.293.2.217. 4. Garber SL, Rintala DH. Pressure ulcers in veterans with spinal cord injury: a retrospective study. J Rehabil Res Dev. 2003; 40(5):433-41. doi: 10.1682/jrrd.2003.09.0433. 5. Court-Brown CM, Rimmer S, Prakash U, McQueen MM. The epidemiology of open long bone fractures. Injury. 1998; 29(7):529-34. doi: 10.1016/s0020-1383(98)00125-9. 6. Chua W, Murphy DP, Siow W, Kagda FH, Thambiah J. Epidemiological analysis of outcomes in 323 open tibial diaphyseal fractures: a nine-year experience. Singapore Med J. 2012; 53(6):385-9. 7. Pollak AN, McCarthy ML, Burgess AR. Short-term wound complications after application of flaps for coverage of traumatic soft-tissue defects about the tibia. The Lower Extremity Assessment Project (LEAP) Study Group. J Bone Joint Surg Am. 2000;82(12):1681-91. 8. BOAST. Guideline to lower limb open fractures. Available at: www.bapras.org.uk/downloaddoc.asp?id=141. Accessed July 31, 2012. 9. Xu YQ, Lin YQ, Li J, et al. Repair and reconstruction of severe leg injuries: retrospective review of eighty-five patients. Chin J Traumatol. 2006; 9(3):131-7. 10. Jagdev SS, Pathak S, Kanani H, Salunke A. Functional Outcome and Incidence of Osteoarthritis in Operated Tibial Plateau Fractures. Arch Bone Jt Surg. 2018 Nov;6(6):508-516. PMID: 30637306; PMCID: PMC6310186. 11. Aslani, H., Nourbakhsh, S. T., Zafarani, Z., Ahmadi-Bani, M., Ananloo, M. E. S., Beigy, M., & Salehi, S. (2016). Platelet-rich plasma for frozen shoulder: a case report. Archives of Bone and Joint Surgery, 4(1), 90. 12.Shafieian R, Matin MM, Rahpeyma A, Fazel A, Sedigh HS, Nabavi AS, Hassanzadeh H, Ebrahimzadeh-Bideskan A. Effects of Human Adipose-derived Stem Cells and Platelet-Rich Plasma on Healing Response of Canine Alveolar Surgical Bone Defects. Arch Bone Jt Surg. 2017 Nov;5(6):406-418. PMID: 29299496; PMCID: PMC5736890. 13. Whitman DH, Berry RL, Green DM. Platelet gel: an autologous alternative to fibrin glue with applications in oral and maxillofacial surgery. J Oral Maxillofac Surg. 1997; 55(11):1294-1299. doi: 10.1016/s0278-2391(97)90187-7. 14. Silver FH, Wang MC, Pins GD. Preparation and use of fibrin glue in surgery. Biomaterials. 1995; 16(12):891-903. doi: 10.1016/0142-9612(95)93113-r. 15. Reuss BL, Cole JD. Effect of delayed treatment on open tibial shaft fractures. Am J Orthop (Belle Mead NJ). 2007; 36(4):215-20. 16. Gopal S, Giannoudis PV, Murray A, Matthews SJ, Smith RM. The functional outcome of severe, open tibial fractures managed with early fixation and flap coverage. J Bone Joint Surg Br. 2004; 86(6):861-7. doi: 10.1302/0301- 620x.86b6.13400. 17. Gustilo RB. Current concepts in the management of open fractures. Instr Course Lect. 1987; 36:359-66. 18. Blick SS, Brumback RJ, Lakatos R, Poka A, Burgess AR. Early prophylactic bone grafting of high-energy tibial fractures. Clin Orthop Relat Res. 1989 ;( 240):21-41. 19. Alsousou J, Thompson M, Hulley P, Noble A, Willett K. The biology of platelet-rich plasma and its application in trauma and orthopaedic surgery: a review of the literature. J Bone Joint Surg Br. 2009; 91(8):987-96. doi: 10.1302/0301- 620X.91B8.22546. 20. Anitua E, Sánchez M, Orive G, Andia I. Delivering growth factors for therapeutics. Trends Pharmacol Sci. 2008; 29(1):37-41. doi: 10.1016/j.tips.2007.10.010. 21. Franchini M, Dupplicato P, Ferro I, De Gironcoli M, Aldegheri R. Efficacy of platelet gel in reconstructive bone surgery. Orthopedics. 2005; 28(2):161-3. doi: 10.3928/0147-7447- 20050201-19. 22. Dougherty P. Transtibial amputees from the Vietnam War: twenty-eight year follow-up. J Bone Joint Surg Am. 2001; 83(3):383-9. doi: 10.2106/00004623-200103000-00010. 23. Crovetti G, Martinelli G, Issi M, et al. Platelet gel for healing cutaneous chronic wounds. Transfus Apher Sci. 2004; 30(2):145-151. doi: 10.1016/j.transci.2004.01.004. 24. Malhotra A, Pelletier MH, Yu Y, Walsh WR. Can platelet-rich plasma (PRP) improve bone healing? A comparison between the theory and experimental outcomes. Arch Orthop Trauma Surg. 2013; 133(2):153-65. doi: 10.1007/s00402-012-1641- 1. 25. Kanthan SR, Kavitha G, Addi S, Choon DS, Kamarul T. Plateletrich plasma (PRP) enhances bone healing in non-united critical-sized defects: a preliminary study involving rabbit models. Injury. 2011; 42(8):782-9. 10.1016/j.injury.2011.01.015. 26. Ravari H, Hamidi-Almadari D, Salimifar M, Bonakdaran S, Parizadeh MR, Koliakos G. Treatment of non-healing wounds with autologous bone marrow cells, platelets, fibrin glue and collagen matrix. Cytotherapy. 2011; 13(6):705-11. doi: 10.3109/14653249.2011.553594. | ||
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