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bhawani, rama, BASANDRAI, DEEPAK, Passi, Kamlesh. (1403). Quantitative Estimation of Integral Doses and Skin Entry Exit Doses during Different Radiation Treatment Delivery Techniques for Craniospinal Irradiation Patients. , 21(3), 147-153. doi: 10.22038/ijmp.2023.71025.2254
rama bhawani; DEEPAK BASANDRAI; Kamlesh Passi. "Quantitative Estimation of Integral Doses and Skin Entry Exit Doses during Different Radiation Treatment Delivery Techniques for Craniospinal Irradiation Patients". , 21, 3, 1403, 147-153. doi: 10.22038/ijmp.2023.71025.2254
bhawani, rama, BASANDRAI, DEEPAK, Passi, Kamlesh. (1403). 'Quantitative Estimation of Integral Doses and Skin Entry Exit Doses during Different Radiation Treatment Delivery Techniques for Craniospinal Irradiation Patients', , 21(3), pp. 147-153. doi: 10.22038/ijmp.2023.71025.2254
bhawani, rama, BASANDRAI, DEEPAK, Passi, Kamlesh. Quantitative Estimation of Integral Doses and Skin Entry Exit Doses during Different Radiation Treatment Delivery Techniques for Craniospinal Irradiation Patients. , 1403; 21(3): 147-153. doi: 10.22038/ijmp.2023.71025.2254

Quantitative Estimation of Integral Doses and Skin Entry Exit Doses during Different Radiation Treatment Delivery Techniques for Craniospinal Irradiation Patients

Iranian Journal of Medical Physics
دوره 21، شماره 3، مرداد و شهریور 2024، صفحه 147-153    اصل مقاله (1.36 M)
نوع مقاله: Original Paper
شناسه دیجیتال (DOI): 10.22038/ijmp.2023.71025.2254
نویسندگان
rama bhawani1؛ DEEPAK BASANDRAI* 2؛ Kamlesh Passi3
1Lovely Professional University
2Lovely Professional University, Jalandhar, Punjab , India
3Department of Radiation Oncology, Mohan Dai Oswal Cancer Hospital and Research Foundation, Ludhiana Punjab 141009 India
چکیده
Introduction: The present study includes a qualitative analysis of skin entry exit doses and Integral doses (ID) utilizing various treatment planning strategies.
Material and Methods: For this study, we have taken 20 patients suffering from medulloblastoma and planned for Craniospinal irradiation (CSI) with Helical Intensity Modulated radiation therapy HIMRT, Helical three dimensional conformal radiation therapy H3DCRT, and Volumetric modulated arc therapy VMAT treatment planning techniques on Accuray Radixact X9 and Elekta Synergy (Agility) linear accelerator.
Results: Various dosimetric parameters like Dmax, Dmean, D80%, D50%, D30%, and D10% have been calculated for skin and skin_ring. Integral doses have been calculated for PTV-Brain and PTV-Spine, taking into consideration at least V95% (target coverage by 95% of the prescribed dose). Statistical analysis was done using SPS software version 22. Mean skin entry and exit doses were [HIMRT=7.07±0.703, H3DCRT = 7.87±0.958 VMAT=4.09±0.706]. For Phase-1mean integral dose for PTV_Brain and PTV_Spine was [HIMRT=11.37±4.458, H3DCRT=12.30±5.00, VMAT=7.21±2.990] and Phase-2 mean integral doses for GTV_Boost was [HIMRT=0.10±0.10   H3DCRT = 0.11±0.117 VMAT=0.03±0.067]. Skin entry exit doses and integral doses were observed to be highest in H3DCRT and then HIMRT. Meanwhile, VMAT plans show minimum entry exit doses and integral doses for Phase 1 and Phase 2.
Conclusion: This study concludes that VMAT treatment planning techniques showing less skin entry exit doses and integral doses compared with helical treatment planning techniques. Taking care of these factors can give better clinical outcomes in terms of less late side effects.
کلیدواژه‌ها
Volumetric Modulated Arc Therapy Helical Tomotherapy Radiation Therapy Three؛ Dimensional Conformal Radiotherapy
مراجع
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