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Pourramazan, Zahra, Bilan, Nemat, Amirikar, Farinaz. (1401). Oxygenation and Ventilation Indices in Relation to the Duration of Mechanical Ventilation in 2-Month to 14-Year-Old Children Admitted to PICU. , 11(3), 17487-17494. doi: 10.22038/ijp.2023.66498.4991
Zahra Pourramazan; Nemat Bilan; Farinaz Amirikar. "Oxygenation and Ventilation Indices in Relation to the Duration of Mechanical Ventilation in 2-Month to 14-Year-Old Children Admitted to PICU". , 11, 3, 1401, 17487-17494. doi: 10.22038/ijp.2023.66498.4991
Pourramazan, Zahra, Bilan, Nemat, Amirikar, Farinaz. (1401). 'Oxygenation and Ventilation Indices in Relation to the Duration of Mechanical Ventilation in 2-Month to 14-Year-Old Children Admitted to PICU', , 11(3), pp. 17487-17494. doi: 10.22038/ijp.2023.66498.4991
Pourramazan, Zahra, Bilan, Nemat, Amirikar, Farinaz. Oxygenation and Ventilation Indices in Relation to the Duration of Mechanical Ventilation in 2-Month to 14-Year-Old Children Admitted to PICU. , 1401; 11(3): 17487-17494. doi: 10.22038/ijp.2023.66498.4991

Oxygenation and Ventilation Indices in Relation to the Duration of Mechanical Ventilation in 2-Month to 14-Year-Old Children Admitted to PICU

Journal of Pediatric Perspectives
مقاله 5، دوره 11، شماره 3، خرداد 2023، صفحه 17487-17494    اصل مقاله (323.05 K)
نوع مقاله: original article
شناسه دیجیتال (DOI): 10.22038/ijp.2023.66498.4991
نویسندگان
Zahra Pourramazan1؛ Nemat Bilan* 2؛ Farinaz Amirikar3
1Pediatric Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
2Professor, Pediatric Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
3Pediatric Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
چکیده
Background: Respiratory diseases are the most common cause of death in the pediatric population and acute or progressive respiratory failure, which requires mechanical ventilation, is the most common cause of children’s hospitalization in the intensive care unit. Despite advances in recent decades regarding the treatment of acute respiratory diseases in children and innovative settings in mechanical ventilation, there are no clear and comprehensive guidelines for the use of mechanical ventilation in children.
Objective: This research aimed to evaluate the correlation between oxygenation and ventilation indices in predicting the duration of mechanical ventilation in children aged two months to 14 years old admitted to PICU.
Methods: In this cross-sectional study, 56 patients were included. The required information was extracted from the patients' clinical records and entered into the prepared questionnaires. They included age, sex, and diagnosis, duration of intubation, extubation time, mechanical ventilation parameters, and blood gas parameters. Patients' blood and ventilation data were collected and calculated from the first day of mechanical ventilation until 7 days later to calculate Oxygenation (OI) and Ventilation (VI) indices.
Results: Pneumonia, the most common cause of hospitalization in the intensive care unit and the need for intubation, was present in our population (82%) due to aspiration and Covid-19 disease. There was a significant relationship between higher levels of FiO2 and longer duration of patients' intubation (P <0.001). The amount of PIP in each of the first days of intubation was significantly correlated with the duration of the study. A significant direct relationship was found between the ventilation index and oxygenation index. (P <0.05) Except for the sixth day, oxygenation index and duration of intubation were significantly correlated. (P <0.05) This means that along with the increase in oxygenation index, the duration of intubation was also increased. Ventilation index and duration of intubation were also significantly correlated, except on the fourth and fifth days (P <0.05). None of the extubated patients required re-intubation. Eventually, a very weak statistical correlation was found between the intubation period and the final result in the form of discharge and recovery of the patient or his death.
Conclusion: Using variables such as gender, PIP and oxygenation, and ventilation indices, in the early days of mechanical ventilation, the prognosis of these patients and better management of their treatment can be judged. It is, finally, emphasized that further studies on larger populations, with more variables and long-term follow-ups are required.
کلیدواژه‌ها
Intubation؛ Oxygenation index؛ Ventilation index؛ Blood gases
مراجع
  1. Navalesi P, Colombo D, Della Corte F. NAVA ventilation. Minerva Anestesiol. 2010; 76(5):346-52.
  2. Zielińska M, Zieliński S, Sniatkowska-Bartkowska A. Mechanical ventilation in children: problems and issues. Adv Clin Exp Med. 2014; 23(5):843-8.
  3. Fontela PS, Piva JP, Garcia PC, Bered PL, Zilles K. Risk factors for extubation failure in mechanically ventilated pediatric patients. Pediatric Critical Care Medicine. 2005; 6(2):166-70.
  4. Ghuman a, khemani r, newth c, Ross p. End tidal alveolar dead space fraction (avdsf) changes during nitric oxide administration. Pediatric critical care medicine. 2014; 15(4_suppl):27.
  5. Farias JA, Fernández A, Monteverde E, Flores JC, Baltodano A, Menchaca A, Poterala R, Pánico F, Johnson M, Dessauer Bv, Donoso A, Zavala I, Zavala C, Troster E, Peña Y, Flamenco C, Almeida H, Nilda V, Esteban A; Latin-American Group for Mechanical Ventilation in Children. Mechanical ventilation in pediatric intensive care units during the season for acute lower respiratory infection: a multicenter study. Pediatric Critical Care Medicine. 2012; 13(2):158-64.
  6. Gilstrap D, MacIntyre N. Patient–ventilator interactions. Implications for clinical management. American journal of respiratory and critical care medicine. 2013; 188(9):1058-68.
  7. José A, Dias EC, Santos VLA, Chiavone PA. Predictive value of blood gas analysis and oxygenation score in weaning of mechanical ventilation. Rev Bras Ter Intensiva. 2001; 13:50-7.
  8. Newth CJL, Venkataraman S, Willson DF, Meert KL, Harrison R, Dean JM, Pollack M, Zimmerman J, Anand KJS, Carcillo JA, Nicholson CE; Eunice Shriver Kennedy National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network. Weaning and extubation readiness in pediatric patients. Pediatric critical care medicine: a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 2009; 10(1):1.
  9. Trachsel D, McCrindle BW, Nakagawa S, Bohn D. Oxygenation index predicts outcome in children with acute hypoxemic respiratory failure. American journal of respiratory and critical care medicine. 2005; 172(2):206-11.
  10. Rocha DACB, Marson FAL, Almeida CCB, Junior AAA, Ribeiro JD. Association between oxygenation and ventilation indices with the time on invasive mechanical ventilation in infants. Pulmonology. 2018; 24(4):241-9.
  11. Erickson S, Schibler A, Numa A, Nuthall G, Yung M, Pascoe E, Wilkins B; Paediatric Study Group; Australian and New Zealand Intensive Care Society. Acute lung injury in pediatric intensive care in Australia and New Zealand—A prospective, multicenter, observational study. Pediatric critical care medicine. 2007; 8(4):317-23.
  12. Kneyber MC, Ilia S, Koopman AA, Van Schelven P, Van Dijk J, Burgerhof JG, Markhorst DG, Blokpoel RGT. Energy transmission in mechanically ventilated children: a translational study. Critical Care. 2020; 24(1):1-8.
  13. Trachsel D, McCrindle BW, Nakagawa S, Bohn D. Oxygenation index predicts outcome in children with acute hypoxemic respiratory failure. American journal of respiratory and critical care medicine. 2005; 172(2):206-11.
  14. Hammond BG, Garcia-Filion P, Kang P, Rao MY, Willis BC, Dalton HJ. Identifying an oxygenation index threshold for increased mortality in acute respiratory failure. Respiratory Care. 2017; 62(10):1249-54.
  15. Almeida-Júnior AA, da Silva MT, Almeida CC, Jácomo AD, Nery BM, Ribeiro JD. Association between ventilation index and time on mechanical ventilation in infants with acute viral bronchiolitis. Jornal de Pediatria. 2005; 81:466-70.
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