سامانه مدیریت نشریات علمی دانشگاه علوم پزشکی مشهد

Jahanshahi, Amirreza, Rezamand, Azim, Vahedi, Amir, Ganjei, Meisam, Falahatian, Masih, Falaki, Reyhaneh, Rahimi, Faezeh, Bani, Ghazaleh, Sadeghi-Bazargani, Yasin. (1401). Pediatric Pancreatoblastoma: A Case Report. , 11(3), 17527-17536. doi: 10.22038/ijp.2023.70357.5180
Amirreza Jahanshahi; Azim Rezamand; Amir Vahedi; Meisam Ganjei; Masih Falahatian; Reyhaneh Falaki; Faezeh Rahimi; Ghazaleh Bani; Yasin Sadeghi-Bazargani. "Pediatric Pancreatoblastoma: A Case Report". , 11, 3, 1401, 17527-17536. doi: 10.22038/ijp.2023.70357.5180
Jahanshahi, Amirreza, Rezamand, Azim, Vahedi, Amir, Ganjei, Meisam, Falahatian, Masih, Falaki, Reyhaneh, Rahimi, Faezeh, Bani, Ghazaleh, Sadeghi-Bazargani, Yasin. (1401). 'Pediatric Pancreatoblastoma: A Case Report', , 11(3), pp. 17527-17536. doi: 10.22038/ijp.2023.70357.5180
Jahanshahi, Amirreza, Rezamand, Azim, Vahedi, Amir, Ganjei, Meisam, Falahatian, Masih, Falaki, Reyhaneh, Rahimi, Faezeh, Bani, Ghazaleh, Sadeghi-Bazargani, Yasin. Pediatric Pancreatoblastoma: A Case Report. , 1401; 11(3): 17527-17536. doi: 10.22038/ijp.2023.70357.5180

Pediatric Pancreatoblastoma: A Case Report

Journal of Pediatric Perspectives
مقاله 8، دوره 11، شماره 3، خرداد 2023، صفحه 17527-17536    اصل مقاله (433.83 K)
نوع مقاله: case report
شناسه دیجیتال (DOI): 10.22038/ijp.2023.70357.5180
نویسندگان
Amirreza Jahanshahi1؛ Azim Rezamand2؛ Amir Vahedi3؛ Meisam Ganjei* 4؛ Masih Falahatian4؛ Reyhaneh Falaki4؛ Faezeh Rahimi5؛ Ghazaleh Bani2؛ Yasin Sadeghi-Bazargani6
1Department of Radiology, Emam Reza Hospital, Tabriz University of Medical Sciences, Tabriz, Iran
2Pediatric Research Center, Children hospital, Medical Faculty, Tabriz University of Medical Sciences, Tabriz, Iran
3Department of Pathology, Tabriz University of Medical Sciences, Tabriz, Iran
4Medical Radiation Sciences Research Group, Tabriz University of Medical Sciences, Tabriz, Iran
5Department of Radiology, Zanjan University of Medical Sciences, Zanjan, Iran
6Medical student, student research committee, Tabriz University of Medical Sciences, Tabriz, Iran
چکیده
Background: Pancreatoblastoma (PB) is an exceedingly uncommon pancreatic tumor arising from pancreatic exocrine cells. It is the most common malignant pancreatic tumor in childhood.
Case presentation: We report a case of PB in a 5-year-old girl who presented to our institution with severe abdominal pain, anorexia, vomiting, and jaundice. Laboratory tests were compatible with cholestasis. Ultrasound imaging showed mild intra- and extrahepatic bile duct dilation as well as a pancreatic mass. A Computed Tomography (CT) scan confirmed a large mass in the head of the pancreas, which was associated with periportal lymphadenopathy as well as anterior and inward displacement of superior mesenteric vessels. Although the mass was unresectable at the time of admission to our center, an open biopsy of the tumor was performed, which revealed a diagnosis of PB. Following six months of neoadjuvant chemotherapy, the size of the tumor was dramatically decreased, allowing the complete resection of it.
Conclusion: When a child presents with a massive solid cystic tumor in the pancreas, the possibility of pancreatoblastoma must be considered. Surgery is utilized to completely remove the tumor, while pathology and immunohistochemistry are used to confirm the diagnosis. Patients with huge tumors or extensive lymphadenopathy typically need neoadjuvant chemotherapy before surgery to downstage their disease.
کلیدواژه‌ها
Pancreatoblastoma,,؛ ,،Computed Tomography,,؛ ,،pancreatic mass,,؛ ,،Case report
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