سامانه مدیریت نشریات علمی دانشگاه علوم پزشکی مشهد

Goel, Akshay, Viswanathan, Vibhu Krishnan, Purudappa, Prabhudev Prasad, Sakthivelan, Vishaal, Mounsamy, Varatharaj, Sambandam, Senthil. (1401). Cost and Early Complication Analysis Following Total Hip Arthroplasty in Parkinson’s Disease Patients: A Propensity-matched Database Study. , 11(1), 47-52. doi: 10.22038/abjs.2022.65048.3120
Akshay Goel; Vibhu Krishnan Viswanathan; Prabhudev Prasad Purudappa; Vishaal Sakthivelan; Varatharaj Mounsamy; Senthil Nathan Sambandam. "Cost and Early Complication Analysis Following Total Hip Arthroplasty in Parkinson’s Disease Patients: A Propensity-matched Database Study". , 11, 1, 1401, 47-52. doi: 10.22038/abjs.2022.65048.3120
Goel, Akshay, Viswanathan, Vibhu Krishnan, Purudappa, Prabhudev Prasad, Sakthivelan, Vishaal, Mounsamy, Varatharaj, Sambandam, Senthil. (1401). 'Cost and Early Complication Analysis Following Total Hip Arthroplasty in Parkinson’s Disease Patients: A Propensity-matched Database Study', , 11(1), pp. 47-52. doi: 10.22038/abjs.2022.65048.3120
Goel, Akshay, Viswanathan, Vibhu Krishnan, Purudappa, Prabhudev Prasad, Sakthivelan, Vishaal, Mounsamy, Varatharaj, Sambandam, Senthil. Cost and Early Complication Analysis Following Total Hip Arthroplasty in Parkinson’s Disease Patients: A Propensity-matched Database Study. , 1401; 11(1): 47-52. doi: 10.22038/abjs.2022.65048.3120

Cost and Early Complication Analysis Following Total Hip Arthroplasty in Parkinson’s Disease Patients: A Propensity-matched Database Study

The Archives of Bone and Joint Surgery
مقاله 6، دوره 11، شماره 1، فروردین 2023، صفحه 47-52    اصل مقاله (459.08 K)
نوع مقاله: RESEARCH PAPER
شناسه دیجیتال (DOI): 10.22038/abjs.2022.65048.3120
نویسندگان
Akshay Goel1؛ Vibhu Krishnan Viswanathan* 2؛ Prabhudev Prasad Purudappa3؛ Vishaal Sakthivelan4؛ Varatharaj Mounsamy5؛ Senthil Nathan Sambandam5
1Department of Orthopaedic Surgery, Joan C. Edwards school of medicine, Marshall University, Huntington, WV, Huntington, West Virginia, USA
2University of Calgary, Calgary, Alberta, Canada
3Department of Orthopedic Surgery, Boston University, Boston VAMC, Boston, Massachusetts, USA
4School of Medicine, University of Texas medical Branch,Texas, USA
5Department of Orthopedic Surgery, University of Texas Southwestern, Dallas VAMC, Dallas, Texas, USA
چکیده
Background: Parkinson’s Disease is a well-known neuromuscular disorder, which affects the stability and gait of 
elderly patients. With the progressive increase in the life span of patients with PD, the problem of degenerative 
arthritis and the consequent need for total hip arthroplasty (THA) in this cohort are rising. There is paucity of data in 
the existing literature regarding the healthcare costs and overall outcome following THA in PD patients. The current 
study was planned to assess the hospital expenditure, details regarding hospital stay, and complication rates for 
patients with PD, who underwent THA. 
Methods: We investigated the National Inpatient Sample data to identify PD patients, who underwent hip 
arthroplasty from 2016 to 2019. Using propensity score, PD patients were matched 1:1 to patients without PD by 
age, gender, non-elective admission, tobacco use, diabetes, and obesity. Chi-square and T-tests were used for 
analyzing categorical and non-categorical variables, respectively (Fischer-Exact test was employed for values<5).
Results: Overall, 367,890 (1927 patients with PD) THAs were performed between 2016 and 2019. Before matching, 
PD group had significantly greater proportion of older patients, males, and non-elective admissions for THA (P<0.001). 
After matching, PD group had higher total hospital costs, longer hospital stay, greater blood loss anemia, and prosthetic 
dislocation (P<0.001). The in-hospital mortality was similar between the two groups. 
Conclusion: Patients with PD undergoing THA required greater proportion of emergent hospital admissions. Based on 
our study, the diagnosis of PD showed significant association with greater cost of care, longer hospital stay, and higher 
post-operative complications. 
Level of evidence: II
کلیدواژه‌ها
Parkinson’s disease؛ Total hip arthroplasty
مراجع
1. Jameson, J Larry.Harrison’s manual of medicine - NLM
Catalog - NCBI. Available at: https://www.ncbi.nlm.
nih.gov/nlmcatalog/101745816. Accessed March 23,
2022.
2. Tysnes OB, Storstein A. Epidemiology of Parkinson’s
disease. J Neural Transm (Vienna). 2017; 124(8):901-
905. doi:10.1007/s00702-017-1686-y
3. Zuckerman LM. Parkinson’s disease and the
orthopaedic patient. J Am Acad Orthop Surg. 2009;
17(1):48-55. doi:10.5435/00124635-200901000-
00007
4. Melton LJ, Leibson CL, Achenbach SJ, et al. Fracture
risk after the diagnosis of Parkinson’s disease:
Influence of concomitant dementia. Mov Disord.
2006;21(9):1361-1367. doi:10.1002/mds.20946
5. Newman JM, Sodhi N, Dalton SE, et al. Does
Parkinson Disease Increase the Risk of Perioperative
Complications After Total Hip Arthroplasty? A
Nationwide Database Study. J Arthroplasty. 2018;
33(7S):S162-S166. doi:10.1016/j.arth.2018.01.006
6. Maradit Kremers H, Larson DR, Crowson CS, et al.
Prevalence of Total Hip and Knee Replacement in the
United States. J Bone Joint Surg Am. 2015;97(17):1386-
1397. doi:10.2106/JBJS.N.01141
7. Kleiner JE, Eltorai AEM, Rubin LE, Daniels AH.
Matched Cohort Analysis of Total Hip Arthroplasty
in Patients With and Without Parkinson’s Disease:
Complications, Mortality, Length of Stay, and Hospital
Charges. J Arthroplasty. 2019; 34(7S):S228-S231.
doi:10.1016/j.arth.2019.03.023
8. Piccinin MA, Sayeed Z, Kozlowski R, Bobba V, Knesek
D, Frush T. Bundle Payment for Musculoskeletal Care:
Current Evidence (Part 1). Orthop Clin North Am.
2018; 49(2):135-146. doi:10.1016/j.ocl.2017.11.002
9. Rondon AJ, Tan TL, Schlitt PK, Greenky MR, Phillips
JL, Purtill JJ. Total Joint Arthroplasty in Patients With
Parkinson’s Disease: Survivorship, Outcomes, and
Reasons for Failure. J Arthroplasty. 2018; 33(4):1028-
1032. doi:10.1016/j.arth.2017.11.017
10.Schroeder JE, Hughes A, Sama A, et al. Lumbar Spine
Surgery in Patients with Parkinson Disease. J Bone
Joint Surg Am. 2015; 97(20):1661-1666. doi:10.2106/
JBJS.N.01049
11.Jämsen E, Puolakka T, Peltola M, Eskelinen A, Lehto
MUK. Surgical outcomes of primary hip and knee
replacements in patients with Parkinson’s disease: a
nationwide registry-based case-controlled study. Bone
Joint J. 2014; 96-B (4):486-491. doi:10.1302/0301-
620X.96B4.33422
12.McClelland S, Baker JF, Smith JS, et al. Impact of
Parkinson’s disease on perioperative complications
and hospital cost in multilevel spine fusion: A
population-based analysis. J Clin Neurosci. 2017;
35:88-91. doi:10.1016/j.jocn.2016.10.008
13.Meek RMD, Allan DB, McPhillips G, Kerr L, Howie
CR. Epidemiology of dislocation after total hip
arthroplasty. Clin Orthop Relat Res. 2006; 447:9-18.
doi:10.1097/01.blo.0000218754.12311.4a
14.Ryu HG, Roh YJ, Oh KJ, et al. Dual mobility articulation
total hip arthroplasty for displaced neck fracture in
elderly with neuromuscular disorder. Injury. 2021;
52(6):1480-1486. doi:10.1016/j.injury.2021.01.005
15.Oichi T, Chikuda H, Ohya J, et al. Mortality and
morbidity after spinal surgery in patients with
Parkinson’s disease: a retrospective matchedpair cohort study. Spine J. 2017; 17(4):531-537.
doi:10.1016/j.spinee.2016.10.024
16.Baker JF, McClelland S, Line BG, et al. In-Hospital
Complications and Resource Utilization Following
Lumbar Spine Surgery in Patients with Parkinson
Disease: Evaluation of the National Inpatient Sample
Database. World Neurosurg. 2017; 106:470-476.
doi:10.1016/j.wneu.2017.07.006

آمار
تعداد مشاهده مقاله: 451
تعداد دریافت فایل اصل مقاله: 337