سامانه مدیریت نشریات علمی دانشگاه علوم پزشکی مشهد

Gholami, Hamideh, Tofighi, Shabnam, Molaei, Behnaz, Dabiri Oskoei, Atousa, Hatami, Robabeh, Garrosi, Lida, Abdi, Roghayeh, Shafaghat Ardabili, Arman. (1401). Association between Corticosteroid Administration in Pregnant Women with COVID-19 and Neonatal Outcomes. , 13(4), 34-38. doi: 10.22038/ijn.2022.63490.2215
Hamideh Gholami; Shabnam Tofighi; Behnaz Molaei; Atousa Dabiri Oskoei; Robabeh Hatami; Lida Garrosi; Roghayeh Abdi; Arman Shafaghat Ardabili. "Association between Corticosteroid Administration in Pregnant Women with COVID-19 and Neonatal Outcomes". , 13, 4, 1401, 34-38. doi: 10.22038/ijn.2022.63490.2215
Gholami, Hamideh, Tofighi, Shabnam, Molaei, Behnaz, Dabiri Oskoei, Atousa, Hatami, Robabeh, Garrosi, Lida, Abdi, Roghayeh, Shafaghat Ardabili, Arman. (1401). 'Association between Corticosteroid Administration in Pregnant Women with COVID-19 and Neonatal Outcomes', , 13(4), pp. 34-38. doi: 10.22038/ijn.2022.63490.2215
Gholami, Hamideh, Tofighi, Shabnam, Molaei, Behnaz, Dabiri Oskoei, Atousa, Hatami, Robabeh, Garrosi, Lida, Abdi, Roghayeh, Shafaghat Ardabili, Arman. Association between Corticosteroid Administration in Pregnant Women with COVID-19 and Neonatal Outcomes. , 1401; 13(4): 34-38. doi: 10.22038/ijn.2022.63490.2215

Association between Corticosteroid Administration in Pregnant Women with COVID-19 and Neonatal Outcomes

Iranian Journal of Neonatology
مقاله 7، دوره 13، شماره 4، دی 2022، صفحه 34-38    اصل مقاله (795.36 K)
نوع مقاله: Original Article
شناسه دیجیتال (DOI): 10.22038/ijn.2022.63490.2215
نویسندگان
Hamideh Gholami* 1؛ Shabnam Tofighi1؛ Behnaz Molaei1؛ Atousa Dabiri Oskoei1؛ Robabeh Hatami2؛ Lida Garrosi1؛ Roghayeh Abdi1؛ Arman Shafaghat Ardabili3
1Department of Obstetrics and Gynecology, School of Medicine, Ayatollah Mousavi Hospital, Zanjan University of Medical Sciences, Zanjan, Iran
2Department of Obstetrics and Gynecology, School of Medicine, Ayatollah Mousavi Hospital, Zanjan University of Medical Sciences, Zanjan, Iran,
3Department of Pediatrics, School of Medicine, Ayatollah Mousavi Hospital, Zanjan University of Medical Sciences, Zanjan, Iran,
چکیده
Background: The evidence for the effect of corticosteroid administration on neonates in pregnant women who tested positive for COVID-19 is rare. This study aims to evaluate the effect of the administration of corticosteroids on pregnant women with COVID-19 on neonatal metabolic outcomes of hypoglycemia and hyperbilirubinemia.
Methods: The present retrospective cohort study was conducted on pregnant women with COVID-19 referred to Mousavi Hospital in Zanjan, Iran in 2020. We compared post-delivery complications in women who had received corticosteroids with a control group. The data were extracted from the medical records of the patients by a resident of the gynecology. The chi-square test was used to compare the rate of hyperbilirubinemia and hypoglycemia between groups.
Results: Of a total of 71 investigated patients, only 32 received non-steroidal anti-inflammatory drugs (NSAIDs),. The mean age of the patients was 29.77±6.87 years and there was not a significant difference between the two groups in terms of age, BMI, education, blood sugar, bilirubin, neonate weight, and 1 and 5-minute Apgar score (P>0.05). In the corticosteroid-receiving group, a significantly higher rate of hypoglycemia (37.5% vs. 7.69%, P=0.002) and hyperbilirubinemia (25% vs. 5.13%, P=0.02) was reported.
Conclusion: The results suggested that the administration of corticosteroids as a treatment modality for pregnant women with COVID-19 is associated with an increased rate of neonatal hypoglycemia and hyperbilirubinemia. Therefore, glycemic control is necessary for neonates born from pregnant women with COVID-19 exposed to corticosteroids during the pregnancy.
 
 
کلیدواژه‌ها
Blood sugar؛ Bilirubin؛ COVID-19؛ Corticosteroids؛ Pregnant women
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