سامانه مدیریت نشریات علمی دانشگاه علوم پزشکی مشهد

Yousefi Zoshk, Mojtaba, Zamanian, Melika, Farshidianfar, Melika, Masoumi, Alireza, Mirimoghaddam, Mohammad Mobin, Bakhshi, Elahe, Azarfar, Anoush. (1401). A comprehensive review of SARS-CoV-2-associated multisystem inflammatory syndrome in children. , (), -. doi: 10.22038/rcm.2022.68251.1414
Mojtaba Yousefi Zoshk; Melika Zamanian; Melika Farshidianfar; Alireza Masoumi; Mohammad Mobin Mirimoghaddam; Elahe Bakhshi; Anoush Azarfar. "A comprehensive review of SARS-CoV-2-associated multisystem inflammatory syndrome in children". , , , 1401, -. doi: 10.22038/rcm.2022.68251.1414
Yousefi Zoshk, Mojtaba, Zamanian, Melika, Farshidianfar, Melika, Masoumi, Alireza, Mirimoghaddam, Mohammad Mobin, Bakhshi, Elahe, Azarfar, Anoush. (1401). 'A comprehensive review of SARS-CoV-2-associated multisystem inflammatory syndrome in children', , (), pp. -. doi: 10.22038/rcm.2022.68251.1414
Yousefi Zoshk, Mojtaba, Zamanian, Melika, Farshidianfar, Melika, Masoumi, Alireza, Mirimoghaddam, Mohammad Mobin, Bakhshi, Elahe, Azarfar, Anoush. A comprehensive review of SARS-CoV-2-associated multisystem inflammatory syndrome in children. , 1401; (): -. doi: 10.22038/rcm.2022.68251.1414

A comprehensive review of SARS-CoV-2-associated multisystem inflammatory syndrome in children

Reviews in Clinical Medicine
مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 20 آذر 1401
نوع مقاله: Review
شناسه دیجیتال (DOI): 10.22038/rcm.2022.68251.1414
نویسندگان
Mojtaba Yousefi Zoshk1؛ Melika Zamanian2؛ Melika Farshidianfar3؛ Alireza Masoumi3؛ Mohammad Mobin Mirimoghaddam2؛ Elahe Bakhshi4؛ Anoush Azarfar* 5
1Department of Pediatrics, Faculty of Medicine, AJA University of Medical Sciences, Tehran, Iran.
2Student Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
3MD, Faculty of Medicine, Islamic Azad University – Mashhad Branch, Mashhad, Iran.
4Faculty of Pharmacy, Islamic Azad University – Damghan Branch, Damghan, Iran.
5Department of Pediatrics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
چکیده
The coronavirus disease 2019 (COVID-19) has afflicted individuals of all ages, which has a high rate of morbidity and fatality. Although most children with COVID-19 infection experience minor symptoms, a growing proportion of COVID-19 infections in children are linked to a novel multisystem inflammatory syndrome with Kawasaki disease-like clinical features. Multisystem inflammatory syndrome in children (MIS-C) is a novel hyperinflammatory syndrome that can impact about any organ system. The most frequent symptoms are fever and gastrointestinal disorders, although neurologic and dermatologic manifestations are also well-documented. The clinical symptoms of MIS-C coincide with those of Kawasaki disease, toxic shock syndrome, and shock syndrome, making diagnosis challenging. Elevated inflammatory markers are common in MIS-C patients, and an abnormal echocardiogram or electrocardiogram may be present. Intravenous immunoglobulin, anticoagulation, and corticosteroids should all be considered in the treatment of MIS-C patients. Even those with significant cardiovascular involvement, the majority of patients recover without complications. Echocardiographic follow-up is required as coronary aneurysms have been documented. This narrative review is to review the epidemiology, pathophysiology, clinical presentations, laboratory findings, diagnostic criteria, and treatment options for MIS-C patients in order to increase pediatricians’ knowledge of this novel syndrome.
کلیدواژه‌ها
Pediatrics؛ MIS-C؛ COVID-19
آمار
تعداد مشاهده مقاله: 551