Evaluating the effect of an Iranian traditional medicine-based herbal candy on body composition and appetite in overweight and obese adults: A preliminary study | ||
Avicenna Journal of Phytomedicine | ||
دوره 13، شماره 2، خرداد و تیر 2023، صفحه 165-176 اصل مقاله (608.74 K) | ||
نوع مقاله: Original Research Article | ||
شناسه دیجیتال (DOI): 10.22038/ajp.2022.21314 | ||
نویسندگان | ||
Maryam Golzar1؛ Effat Saghi1؛ Hassan Rakhshandeh2؛ Zahra Dehnavi1؛ Ali Jafarzadeh Esfehani3؛ Mohsen Nematy* 1 | ||
1Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran | ||
2Pharmacological Research Center of Medicinal Plants, Mashhad University of Medical Sciences, Mashhad, Iran | ||
3Metabolic Syndrome Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran | ||
چکیده | ||
Objective: Obesity is an important public health concern in the world. Considering the limited medications and their side effects and lack of a known effective way to reduce appetite, traditional herbs have been considered a complementary treatment for obesity. Therefore, this study was conducted to evaluate the effect of an Iranian Traditional Medicine (ITM)-based herbal candy on body composition and appetite in obese and overweight adults. Materials and Methods: In this preliminary study that conducted in nutrition clinic of Ghaem Hospital of Mashhad, participants were selected from overweight and obese people and randomly assigned to either groups. Participants in the intervention group received herbal candy which contained a combination of Portulaca oleracea, Plantago psyllium, and peanut oil, while participants in the control group received placebo candy for 8 weeks. The primary (appetite response, and weight changes) and secondary (body mass index (BMI), anthropometric parameters, blood pressure, and laboratory variables) outcomes were collected at baseline and during the intervention. Results: Fifty participants between the age of 18 and 65 years old were included in this study. Herbal candy resulted in a greater reduction in mean weight and BMI compared to placebo (p<0.001). Mean of hunger, satiety, and eating capacity indicators decreased more significantly at all three intervals (30 min after herbal candy, 1 hour after meal and 2 hours after meal) at lunch and dinner meal in the intervention group compared to the control group (p<0.05). Conclusion: A combination of produced herbal candy at a dose of 4 g (2 pcs), given half an hour before each meal for 8 weeks, can be effective in reducing weight and appetite in obese and overweight people. | ||
کلیدواژهها | ||
Iranian Traditional Medicine؛ Overweight؛ Obesity؛ Weight reduction؛ Herbal medicine؛ Herbal candy | ||
مراجع | ||
Abdullah A, Wolfe R, Stoelwinder JU, de Courten M, Stevenson C, Walls HL, Peeters A. 2011. The number of years lived with obesity and the risk of all-cause and cause-specific mortality. Int J Epidemiol, 40: 985-996. Akuamoah-Boateng L, Iyer SS, Sales RL, Lokko P, Lartey A, Monteiro JB, Mattes RD. 2007. Effect of peanut oil consumption on energy balance. J Appl Res, 7: 185-196. Alper CM, Mattes RD. 2002. Effects of chronic peanut consumption on energy balance and hedonics. Int J Obes Relat Metab Disord, 26: 1129-1137. Behan DF, Cox SH, Lin Y, Pai J, Pedersen HW, Yi M. 2010. Obesity and its relation to mortality and morbidity costs. SOA, 59. Blundell J, Rogers P. 1991. Satiating power of food. Hum Biol, 6: 723-733. Brennan AM, Sweeney LL, Liu X, Mantzoros CS. 2010. Walnut consumption increases satiation but has no effect on insulin resistance or the metabolic profile over a 4‐ day period. Obesity (Silver Spring), 18: 1176-1182. Brum JM, Gibb RD, Peters JC, Mattes RD. 2016. Satiety effects of psyllium in healthy volunteers. Appetite, 105: 27-36. Coelho SB, de Sales RL, Iyer SS, Bressan J, Costa NM, Lokko P, Mattes RD. 2006. Effects of peanut oil load on energy expenditure, body composition, lipid profile, and appetite in lean and overweight adults. Nutrition, 22: 585-592. Eisenstein J, Roberts SB, Dallal G, Saltzman E. 2002. High-protein weight-loss diets: are they safe and do they work? A review of the experimental and epidemiologic data. Nutr Rev, 60: 189-200. EI-Sayed MI. 2011. Effects of Portulaca oleracea L. seeds in treatment of type-2 diabetes mellitus patients as adjunctive and alternative therapy. J Ethnopharmacol, 137: 643-651. Gorjani SE. 1976. Zakhireh Kharazmshahi (Treasure of Kharazmshah). Saidi Sirjani A (Ed). Photoprint of the manuscript, pp. 153- 156, Tehran, Association of National Artifacts. Galisteo M, Sánchez M, Vera R, González M, Anguera A, Duarte J, Zarzuelo A. 2005. A diet supplemented with husks of Plantago ovata reduces the development of endothelial dysfunction, hypertension, and obesity by affecting adiponectin and TNFα in obese Zucker rats. J Nutr, 135: 2399- 2404. Hollis J, Mattes R. 2007. Effect of chronic consumption of almonds on body weight in healthy humans. Br J Nutr, 98: 651-656. Hylander B, Rössner S. 1983. Effects of dietary fiber intake before meals on weight loss and hunger in a weight‐reducing club. Acta Med Scand, 213: 217-220. Ibn Sina A. 2007. Al-Qanun Fi'l Tibb. (Canon of medicine). Masoudi A (Ed), pp. 361, Kashan, Morsal. Iyer SS, Boateng LA, Sales RL, Coelho SB, Lokko P, Monteiro JB, Costa NM, Mattes RD. 2006. Effects of peanut oil consumption on appetite and food choice. Int J Obes (Lond), 30: 704-710. Jenkins DJ, Hu FB, Tapsell LC, Josse AR, Kendall CW. 2008. Possible benefit of nuts in type 2 diabetes. J Nutr, 138: 1752S1756S. Khorasani A. 1992. Makhzan al-Adwiah (Drug Treasure).(Reprinted from a copy which was printed in Calcutta dated in 1844), pp.433, Tehran, Enqelab-E Eslami Publishing And Educational Organization. Kirkmeyer SV, Mattes RD. 2000. Effects of food attributes on hunger and food intake. Int J Obes Relat Metab Disord, 24: 1167- 1175. Lan S, Fu-er L. 2003. Effects of Portulaca oleracea on insulin resistance in rats with type 2 diabetes mellitus. Chin J Integr Med, 9: 289-292. Mattes RD, Kris-Etherton PM, Foster GD. 2008. Impact of peanuts and tree nuts on body weight and healthy weight loss in adults. Nutr J, 138: 1741S-1745S. Mohammed MS, Sendra S, Lloret J, Bosch I. 2018. Systems and WBANs for controlling obesity. J Healthc Eng, 2018: 1564748. Näslund E, Barkeling B, King N, Gutniak M, Blundell JE, Holst JJ, Rössner S, Hellström PM. 1999. Energy intake and appetite are suppressed by glucagon-like peptide-1 (GLP-1) in obese men. Int J Obes Relat Metab Disord, 23: 304-311. Neves Ribeiro D, Gonçalves Alfenas Rde C, Bressan J, Brunoro Costa NM. 2013. The effect of oilseed consumption on appetite and on the risk of developing type 2 diabetes mellitus. Nutr Hosp, 28: 296-305. Pereira MA, Ludwig DS. 2001. Dietary fiber Golzar et al. AJP, Vol. 13, No. 2, Mar-Apr 2023 176 and body-weight regulation: observations and mechanisms. Pediatr Clin North Am, 48: 969-980. Rajaram S, Sabaté J. 2006. Nuts, body weight and insulin resistance. Br J Nutr, 96 Suppl 2: S79-S86. Razi M. 1998. Razi bank information. Hatami H, Panahi MR (Eds), pp. 245, Tehran, Ministry of Health and Medical Education. Reis CE, Ribeiro DN, Costa NM, Bressan J, Alfenas RC, Mattes RD. 2013. Acute and second-meal effects of peanuts on glycaemic response and appetite in obese women with high type 2 diabetes risk: a randomised cross-over clinical trial. Br J Nutr, 109: 2015-2023. Rigaud D, Paycha F, Meulemans A, Merrouche M, Mignon M. 1998. Effect of psyllium on gastric emptying, hunger feeling and food intake in normal volunteers: a double blind study. Eur J Clin Nutr, 52: 239-245. Rodrı́guez-Morán M, Guerrero-Romero F, Lazcano-Burciaga G. 1998. Lipid-and glucose-lowering efficacy of plantago psyllium in type II diabetes. J Diabetes Complications, 12: 273-278. Sahebkar-Khorasani M, Jarahi L, Cramer H, Safarian M, Naghedi-Baghdar H, Salari R, Behravanrad P, Azizi H. 2019. Herbal medicines for suppressing appetite: A systematic review of randomized clinical trials. Complement Ther Med, 44: 242-252. Salas-Salvadó J, Farrés X, Luque X, Narejos S, Borrell M, Basora J, Anguera A, Torres F, Bulló M, Balanza R. 2008. Effect of two doses of a mixture of soluble fibres on body weight and metabolic variables in overweight or obese patients: a randomised trial. Br J Nutr, 99: 1380-1387. Smith GP. 1998. Satiation: from gut to brain, pp. 51, USA, OUP. Swinburn BA, Sacks G, Hall KD, McPherson K, Finegood DT, Moodie ML, Gortmaker SL. 2011. The global obesity pandemic: shaped by global drivers and local environments. Lancet, 378: 804-814. Turnbull W, Thomas H. 1995. The effect of a Plantago ovata seed containing preparation on appetite variables, nutrient and energy intake. Int J Obes Relat Metab Disord, 19: 338-342. van Marken Lichtenbelt WD, Mensink RP, Westerterp KR. 1997. The effect of fat composition of the diet on energy metabolism. Z Ernahrungswiss, 36: 303- 305. Zhou YX, Xin HL, Rahman K, Wang SJ, Peng C, Zhang H. 2015. Portulaca oleracea L.: A review of phytochemistry and pharmacological effects. Biomed Res Int, 2015: 925631. | ||
آمار تعداد مشاهده مقاله: 10,727 تعداد دریافت فایل اصل مقاله: 460 |