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Mosallanejad, Asieh, Raoufi, Masoomeh, Shakiba, marjan, Saneifard, Hedieh, Alaee, Mohammadeza, Rajabifar, Dina. (1401). Investigating Carotid Intima Media Thickness in Children with Type 1 Diabetes and Its Relationship with HbA1c, Cholesterol, Duration of Disease and BMI: A Cross-Sectional Study. , 10(10), 16817-16824. doi: 10.22038/ijp.2022.66539.4992
Asieh Mosallanejad; Masoomeh Raoufi; marjan Shakiba; Hedieh Saneifard; Mohammadeza Alaee; Dina Rajabifar. "Investigating Carotid Intima Media Thickness in Children with Type 1 Diabetes and Its Relationship with HbA1c, Cholesterol, Duration of Disease and BMI: A Cross-Sectional Study". , 10, 10, 1401, 16817-16824. doi: 10.22038/ijp.2022.66539.4992
Mosallanejad, Asieh, Raoufi, Masoomeh, Shakiba, marjan, Saneifard, Hedieh, Alaee, Mohammadeza, Rajabifar, Dina. (1401). 'Investigating Carotid Intima Media Thickness in Children with Type 1 Diabetes and Its Relationship with HbA1c, Cholesterol, Duration of Disease and BMI: A Cross-Sectional Study', , 10(10), pp. 16817-16824. doi: 10.22038/ijp.2022.66539.4992
Mosallanejad, Asieh, Raoufi, Masoomeh, Shakiba, marjan, Saneifard, Hedieh, Alaee, Mohammadeza, Rajabifar, Dina. Investigating Carotid Intima Media Thickness in Children with Type 1 Diabetes and Its Relationship with HbA1c, Cholesterol, Duration of Disease and BMI: A Cross-Sectional Study. , 1401; 10(10): 16817-16824. doi: 10.22038/ijp.2022.66539.4992

Investigating Carotid Intima Media Thickness in Children with Type 1 Diabetes and Its Relationship with HbA1c, Cholesterol, Duration of Disease and BMI: A Cross-Sectional Study

Journal of Pediatric Perspectives
مقاله 7، دوره 10، شماره 10، دی 2022، صفحه 16817-16824    اصل مقاله (287.2 K)
نوع مقاله: original article
شناسه دیجیتال (DOI): 10.22038/ijp.2022.66539.4992
نویسندگان
Asieh Mosallanejad1؛ Masoomeh Raoufi2؛ marjan Shakiba3؛ Hedieh Saneifard4؛ Mohammadeza Alaee5؛ Dina Rajabifar* 6
1Imam Hossein Medical Center, Shahid Beheshti University of Medical science, Tehran, Iran.
2Assistant Professor of Radiology Department of Radiology, School of Medicine Imam Hossein Hospital Shahid Beheshti University of Medical Sciences, Tehran, Iran
3department of pediatric endocrinology and metabolism, Mofid children hospital, Shahid Beheshti university of medical science
4Assistant Professor of Pediatric Endocrinology, Shahid Beheshti University of Medical Sciences, Tehran- Iran
5Pediatric Endocrinologist Associate Professor, Shahid beheshti University of Medical Sciences
6school of medicine, shahid beheshti university of medical sciences, Tehran , Iran
چکیده
Background: internal carotid intima thickness has been identified as a predictor of atherosclerosis. Patients with type 1 diabetes are at risk for macrovascular complications. Atherosclerosis is 2 to 4 times more common in patients with diabetes, which exposes them to mortality and morbidity. The aim of this study was to determine the thickness of internal carotid intima thickness in children and adolescents with type 1 diabetes and its relationship with cardiovascular risk factors in Iranian children and adolescents with type 1 diabetes.
Method: The present study is a cross-sectional study that was performed in Mofid and Imam Hossein hospitals in Tehran from 2020 to 2021. A total of 91 patients with type 1 diabetes in the age range of 6-18 years, who have been diagnosed with diabetes for at least three years, were included in the study as a diabetic group.
Result: In total, 91 children and adolescents with type 1 diabetes were included in this study, of which 44 (48.4%) were boys and 47 (51.6%) were girls. The mean age of patients was 12.24 ± 3.17 and ranged from 6 to 18 years. The mean age of the patients at the time of diagnosis was 5.86 ± 2.98. In this study, blood pressure of 6 patients (6.6%) was abnormal and the rest had normal blood pressure. In addition, the mean duration of disease in this study was 6.3 ± 2.57 years. The insulin of most patients (93.2%) was Analogue and only 8.8% of patients used Neutral Protamine Hagedorn (NPH) and Regular. The thickness of the intima of the right internal carotid artery is 0.54 ± 0.05 and the thickness of the intima of the left internal carotid artery is 0.48 ± 0.07.
Conclusion: According to the results of this study, none of the factors of disease duration, age of onset, blood pressure, cholesterol, triglycerides, LDL (Low-Density Lipoprotein), HDL (High-Density Lipoprotein), HbA1C (Hemoglobin A1c), history of CHD (Coronary Heart Disease) and hyperlipidemia were significantly associated with the thickness of the intima of internal carotid artery. However, body mass index showed a significant relationship with the thickness of the left internal carotid intima.
کلیدواژه‌ها
BMI؛ Cholesterol؛ Diabetes mellitus؛ HbA1c؛ Carotid Intima Media Thickness
مراجع
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