Importance of IL-1β in SARS-CoV-2 infection | ||
| Journal of Pediatric Perspectives | ||
| مقاله 15، دوره 10، شماره 9، آذر 2022، صفحه 16745-16757 اصل مقاله (645.11 K) | ||
| نوع مقاله: review article | ||
| شناسه دیجیتال (DOI): 10.22038/ijp.2022.66782.5005 | ||
| نویسندگان | ||
| Emad Behboudi1؛ Hossein Teimouri1؛ Vahideh Hamidi-Sofiani2؛ Ali Memarian* 1 | ||
| 1Golestan University of Medical Sciences | ||
| 2Department of Microbiology, Golestan University of Medical Sciences, Gorgan, Iran. | ||
| چکیده | ||
| Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) provokes the host immune responses and induces severe respiratory syndrome by overreaction of immune cells. IL-1β is a pro-inflammatory cytokine highly associated with the related inflammation and cytokine storm, and several IL-1β antagonists are being used to treat cytokine release syndrome (CRS). Accordingly, some studies and clinical trials are investigating the effects of IL-1β antagonists for controlling Coronavirus disease 2019 (COVID-19) associated CRS. Here, we will review any interaction and association between IL-1β and SARS-CoV-2 infection. | ||
| کلیدواژهها | ||
| SARS-CoV2؛ IL-1β؛ COVID-19؛ Cytokine storm؛ Inflammation | ||
| مراجع | ||
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