سامانه مدیریت نشریات علمی دانشگاه علوم پزشکی مشهد

Zarifi, Elham, Sadeghi-Bojd, Simin, Teimouri, Alireza. (1401). Clinical Signs and Causes of Chronic Kidney Disease in Pediatrics. , 10(8), 16434-16448. doi: 10.22038/ijp.2022.65403.4934
Elham Zarifi; Simin Sadeghi-Bojd; Alireza Teimouri. "Clinical Signs and Causes of Chronic Kidney Disease in Pediatrics". , 10, 8, 1401, 16434-16448. doi: 10.22038/ijp.2022.65403.4934
Zarifi, Elham, Sadeghi-Bojd, Simin, Teimouri, Alireza. (1401). 'Clinical Signs and Causes of Chronic Kidney Disease in Pediatrics', , 10(8), pp. 16434-16448. doi: 10.22038/ijp.2022.65403.4934
Zarifi, Elham, Sadeghi-Bojd, Simin, Teimouri, Alireza. Clinical Signs and Causes of Chronic Kidney Disease in Pediatrics. , 1401; 10(8): 16434-16448. doi: 10.22038/ijp.2022.65403.4934

Clinical Signs and Causes of Chronic Kidney Disease in Pediatrics

International Journal of Pediatrics
مقاله 1، دوره 10، شماره 8، آبان 2022، صفحه 16434-16448    اصل مقاله (665.92 K)
نوع مقاله: original article
شناسه دیجیتال (DOI): 10.22038/ijp.2022.65403.4934
نویسندگان
Elham Zarifi1؛ Simin Sadeghi-Bojd2؛ Alireza Teimouri* 3
1General Physician, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
2Pediatric Nephrologist, Children & Adolescent Health Research Center, Resistant Tuberculosis Institute, School of Medicine, Zahedan Univ Med Sci, Zahedan 9816743111, Iran.
3Demographer, Children and Adolescents Health research center, Research Institute of cellular and Molecular Science in Infectious Diseases , Zahedan University of Medical Science's, Zahedan, Iran
چکیده
Background: Chronic kidney disease (CKD) is a worldwide medical condition with increasing frequency that impairs the quality of life of children. This study aimed to assess the clinical signs and causes of CKD in children in Zahedan, Iran.
Methods: This cross-sectional study was run on 489 children up to 20 years with stages of 3 to 5 CKDs, in Zahedan during 2010-2019. Informed written consent was obtained from the patients’ parents. Data analysis was performed by SPSS 20 considering 0.05 as significant level.
Results: Amongst the clinical manifestations, edema (16.4%), (FTT) (13.5%), urinary symptoms (12.3%) and vomiting (11.5%) were more common and congenital structural anomalies (41.7%) were the most common cause of hospital admission. From among the studied children with CKD, 65.8% had stage 5, about 44.4% had conservative treatment and in total, 19.00% died. Most of the laboratory parameters were different in death and survival cases, for instance, Systolic and diastolic BP were higher in deaths when platelet blood was lower. Main causes of CKD (congenital structural anomalies, cystic/hereditary/congenital disease, glomerular diseases, Renal Tubular Disease, unknown origin and stone) had a significant association with gender (X2=13.42, p=0.02), treatments (X2=70.77, p<0.001), stage of CKD (X2=40.31, p<0.001) and survival (X2=11.59, p=0.041). Stages of CKD had a significant relation with treatment (X2=118.18, p<0.001), and survival (X2=26.5, p<0.001).
Conclusion: The causes of CKD were significantly associated with treatments, stage of CKD, and survival. Stages of CKD had significant associations with treatment and survival. Therefore, more attention to children with these signs is essential for early diagnosis and proper treatment.
کلیدواژه‌ها
Clinical Signs؛ Causes؛ Chronic Kidney Diseases؛ Pediatric
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