سامانه مدیریت نشریات علمی دانشگاه علوم پزشکی مشهد

Sadabadi, Fatemeh, Asadi, Zahra, Heidari Bakavoli, Alireza, Darroudi, Susan, Saberi-Karimian, Maryam, Saljoughian, Saniya, Shahi, Maryam, Safarian, Mohammad, Nematy, Mohsen, Ferns, Gordon A., Ghayour-Mobarhan, Majid, Mouhebati, Mohsen. (1401). Association of Serum Anti-Heat Shock Protein 27 Antibody with Obesity Risk among Healthy Individuals in MASHAD Study. , 10(3), 1010-1016. doi: 10.22038/jctm.2022.66266.1388
Fatemeh Sadabadi; Zahra Asadi; Alireza Heidari Bakavoli; Susan Darroudi; Maryam Saberi-Karimian; Saniya Saljoughian; Maryam Shahi; Mohammad Safarian; Mohsen Nematy; Gordon A. Ferns; Majid Ghayour-Mobarhan; Mohsen Mouhebati. "Association of Serum Anti-Heat Shock Protein 27 Antibody with Obesity Risk among Healthy Individuals in MASHAD Study". , 10, 3, 1401, 1010-1016. doi: 10.22038/jctm.2022.66266.1388
Sadabadi, Fatemeh, Asadi, Zahra, Heidari Bakavoli, Alireza, Darroudi, Susan, Saberi-Karimian, Maryam, Saljoughian, Saniya, Shahi, Maryam, Safarian, Mohammad, Nematy, Mohsen, Ferns, Gordon A., Ghayour-Mobarhan, Majid, Mouhebati, Mohsen. (1401). 'Association of Serum Anti-Heat Shock Protein 27 Antibody with Obesity Risk among Healthy Individuals in MASHAD Study', , 10(3), pp. 1010-1016. doi: 10.22038/jctm.2022.66266.1388
Sadabadi, Fatemeh, Asadi, Zahra, Heidari Bakavoli, Alireza, Darroudi, Susan, Saberi-Karimian, Maryam, Saljoughian, Saniya, Shahi, Maryam, Safarian, Mohammad, Nematy, Mohsen, Ferns, Gordon A., Ghayour-Mobarhan, Majid, Mouhebati, Mohsen. Association of Serum Anti-Heat Shock Protein 27 Antibody with Obesity Risk among Healthy Individuals in MASHAD Study. , 1401; 10(3): 1010-1016. doi: 10.22038/jctm.2022.66266.1388

Association of Serum Anti-Heat Shock Protein 27 Antibody with Obesity Risk among Healthy Individuals in MASHAD Study

Journal of Cardio-Thoracic Medicine
مقاله 2، دوره 10، شماره 3، آذر 2022، صفحه 1010-1016    اصل مقاله (1.1 M)
نوع مقاله: Original Article
شناسه دیجیتال (DOI): 10.22038/jctm.2022.66266.1388
نویسندگان
Fatemeh Sadabadi1، 2؛ Zahra Asadi2؛ Alireza Heidari Bakavoli3؛ Susan Darroudi4؛ Maryam Saberi-Karimian4، 5؛ Saniya Saljoughian2؛ Maryam Shahi6؛ Mohammad Safarian7؛ Mohsen Nematy7؛ Gordon A. Ferns8؛ Majid Ghayour-Mobarhan* 2، 3، 4؛ Mohsen Mouhebati* 3
1Cutaneous Leishmaniasis Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
2Metabolic Syndrome Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
3Cardiovascular Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
4International UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.
5Lung Diseases Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
6Blood Borne Infections Research Center, Academic Center for Education, Culture and Research (ACECR), Razavi Khorasan Branch, Mashhad, Iran.
7Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
8Department of Medical Education, Brighton & Sussex Medical School, Brighton, BN1 9PH, UK.
چکیده
Introduction: The association between the serum antibody titer of several heat shock proteins (HSPs) and cardiovascular disease (CVD) risk factors so far has been the subject of several previous studies.
Aim: To evaluate the association of adiposity indices and HSP-27 antibody titers in healthy individuals.
Materials and Methods: Overall 4823 individuals were recruited from Mashhad Stroke and Heart Atherosclerotic Disorders Study (MASHAD study), that included 1496 individuals with normal-weight (body mass index (BMI) <25 kg/m2), 1975 individuals with over-weight (BMI 25-30 kg/m2), and 1352 individuals with obesity (BMI≥ 30 kg/m2).
Results: The serum anti-HSP-27 antibody titers were not significantly different among obese individuals [0.21 (0.11 – 0.34) absorbency unit (AU)], over-weight individuals [0.19 (0.10 – 0.33) AU] and normal-weight individuals [0.19 (0.10 – 0.33) AU].
Conclusions: we have found no significant relationship among anti-HSP-27 antibody concentration and degrees of adiposity among Iranian adults.
کلیدواژه‌ها
Cardiovascular disease؛ Heat shock proteins؛ Obesity
مراجع
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