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Kashaki, Mandana, Saboute, Maryam, Esmaeili Allafi, Maryam, Norouzi, Elahe. (1401). Is Maternal Hypertension a Reducing Factor for Intraventricular Hemorrhage in Iranian Preterm Newborns?. , 10(8), 16469-16476. doi: 10.22038/ijp.2022.63523.4840
Mandana Kashaki; Maryam Saboute; Maryam Esmaeili Allafi; Elahe Norouzi. "Is Maternal Hypertension a Reducing Factor for Intraventricular Hemorrhage in Iranian Preterm Newborns?". , 10, 8, 1401, 16469-16476. doi: 10.22038/ijp.2022.63523.4840
Kashaki, Mandana, Saboute, Maryam, Esmaeili Allafi, Maryam, Norouzi, Elahe. (1401). 'Is Maternal Hypertension a Reducing Factor for Intraventricular Hemorrhage in Iranian Preterm Newborns?', , 10(8), pp. 16469-16476. doi: 10.22038/ijp.2022.63523.4840
Kashaki, Mandana, Saboute, Maryam, Esmaeili Allafi, Maryam, Norouzi, Elahe. Is Maternal Hypertension a Reducing Factor for Intraventricular Hemorrhage in Iranian Preterm Newborns?. , 1401; 10(8): 16469-16476. doi: 10.22038/ijp.2022.63523.4840

Is Maternal Hypertension a Reducing Factor for Intraventricular Hemorrhage in Iranian Preterm Newborns?

Journal of Pediatric Perspectives
مقاله 4، دوره 10، شماره 8، آبان 2022، صفحه 16469-16476    اصل مقاله (384.53 K)
نوع مقاله: original article
شناسه دیجیتال (DOI): 10.22038/ijp.2022.63523.4840
نویسندگان
Mandana Kashaki1؛ Maryam Saboute2؛ Maryam Esmaeili Allafi3؛ Elahe Norouzi* 4
1Associate Professor of Neonatology, Shahid Akbarabadi Clinical Research Development Unit (ShACRDU), Iran University of Medical Sciences(IUMS), School of Medicine
21Shahid Akbarabadi Clinical Research Development Unit (ShACRDU), School of Medicine, Iran University of Medical Sciences (IUMS)
3Department of Pediatrics, School of Medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran.
4Pediatric growth and development research center, Iran University of Medical Sciences (IUMS), School of Medicine
چکیده
Background: Hypertensive disorders of pregnancy including preeclampsia can be associated with preterm birth and infant mortality and morbidity. It seems that intraventricular hemorrhage (IVH) in preterm neonates born to hypertensive mothers is less common compared to the other ones. In this study, we assessed the relationship between hypertensive disorders of pregnant mothers and the incidence of intraventricular hemorrhage in preterm neonates weighing less than 1500 grams.
Methods: In this case-control study, 305 singleton preterm neonates with a birth weight less than 1500 g were entered. The presence of IVH in all preterm neonates was assessed using brain ultrasonography and its correlation to hypertensive disorders of their mothers were evaluated.
Results: The prevalence of preeclampsia in mothers with and without pre pregnancy hypertension was 40%, and 15.09% respectively. The prevalence of IVH in preterm neonates was 26.9% (n=82). The incidence of IVH in preterm neonates of mothers with and without preeclampsia was 16.07%, and 29.31%, respectively (p=0.028). The prevalence of IVH in preterm neonates of mothers with hypertension and without hypertension was 12.5% and 29.05%, respectively (p=0.018). Preterm neonates with IVH had a lower mean birth weight, smaller gestational age and lower Apgar scores compared to preterm neonates without IVH with p values of <0.001, <0.001 and <0.01, respectively.
Conclusion: Hypertensive disorders of pregnancy increase the risk of preterm delivery, but the incidence of IVH in preterm neonates weighing less than 1500 gr is lower in infants born to mothers with hypertension including preeclampsia compared to those born to non-hypertensive mothers. And also lower gestational age, birth weight, and Apgar scores were important predicting factors for IVH in preterm neonates.
کلیدواژه‌ها
Preeclampsia؛ Maternal hypertension؛ Intraventricular hemorrhage؛ Prematurity؛ newborn
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