Antioxidant and anti-atherosclerotic potential of Banana (Musa spp): A review of biological mechanisms for prevention and protection against atherosclerosis | ||
Avicenna Journal of Phytomedicine | ||
دوره 13، شماره 3، مرداد و شهریور 2023، صفحه 240-254 اصل مقاله (646.49 K) | ||
نوع مقاله: Review Article | ||
شناسه دیجیتال (DOI): 10.22038/ajp.2022.20616 | ||
نویسنده | ||
Carlos Kusano Bucalen Ferrari* | ||
Institute of Biological and Health Sciences (ICBS), Federal University of Mato Grosso (UFMT), Barra do Garças, Brazil | ||
چکیده | ||
Objective: To review the antioxidant and anti-atherosclerotic potential of whole banana, banana flour, and its bioactive compounds. Materials and Methods: A non-systematic review of the literature covering the past 20 years, using the following databases and searching bases: PUBMED/MEDLINE: https://www.ncbi.nlm.nih.gov/pubmed/; Google Scholar: https://scholar.google.com.br/; and “Literatura Latinoamericana em Ciências da Saúde”/Latin American Literature in Life Sciences [LILACS]: http://lilacs.bvsalud.org/, was done. Studies with incomplete methodology and design were excluded. Results: Bananas from different species are a good source of carbohydrates, dietary fiber, proteins, polyunsaturated fatty acids, potassium, carotenoids, flavonoids, vitamin C and E, phytosterols, gallocatechin, catechin, and other polyphenols. Some of these compounds play trigger important biological roles as antioxidants or anti-atherosclerotic and cardiovascular protective substances. This review summarizes and explains thirteen protective biological mechanisms of banana bioactive compounds and banana products. Conclusion: Including banana and its products in dietary menus, in food products and nutraceuticals should improve cardiovascular health of the populations. | ||
کلیدواژهها | ||
LDL؛ Triglyceride؛ Antioxidant؛ Lutein؛ Catechin؛ Quercetin | ||
مراجع | ||
Ahmad BA, Zakariyya UA, Abubakar M, Sani MM, Ahmad MA. 2019. Pharmacological activities of Banana. In: Jideani AIO, Anyasi, TA (Eds.). Banana NutritionFunction and Processing Kinetics, pp.1- 20, London, IntechOpen. Akinlolu AA, Ghazali OK, Salau BA, Otulana JO, Omowunmi M. 2013. Musa sapientum attenuates total antioxidant and lipid profile values in rats with indomethacin-induced gastric ulceration. Cel Memb Free Rad Res, 5: 236-243. Al Amri FS, Hossain MA. 2018. Comparison of total phenols, flavonoids, and antioxidant potential of local and imported ripe bananas. Egypt J Bas Appl Sci, 5: 245-251. Anyasi TA, Jideani ALO, Mchau GRA. 2018. Phenolics and essential mineral profile of organic acid pretreated unripe banana flour. Food Res Int, 104: 100-109. Aquino CF, Salomão LC, Pinheiro-Sant‟ana HM, Ribeiro SMR, De Siqueira DL, Cecon PR. 2018. Carotenoids in the pulp and peel from 15 cultivars in two ripening stages. Rev Ceres, 65: 217-226. Arora A, Choudhary D, Agarwal G, Singh VP. 2008. Compositional variation in bcarotene content, carbohydrate and antioxidant enzymes in selected banana cultivars. Int J Food Sci Technol, 43: 1913-1921. Ayala A, Muñoz MF, Argüeles S. 2014. Lipid peroxidation: production, metabolism, and signaling mechanisms of malondialdehyde and 4-hydroxy-2- nonenal. Oxid Med Cel Longev, 2014: 360438. Babu MA, Suriyakala MA, Gothandam KM. 2012. Varietal impact on phytochemical contents and antioxidant properties of Musa acuminata (Banana). J Pharm Sci Res, 4: 1950-1955. Baldi A, Pandit MK, Ranka P. 2012. Amelioration of in-vivo antioxidant activity by banana extracts. Int J Pharm Biol Arch, 3: 157-161. Bakour M, El Menyiy N, El Ghouizi A, Lyoussi B. 2021. Hypoglycemic, hypolipidemic, and hepato-protective effect of bee bread in streptozotocininduced diabetic rats. Avicenna J Phytomed, 11: 343-352. Bhaskar JJ, Mahadevama S, Chilkunda ND, Salimath PV. 2012. Banana (Musa sp. var. elakki bale) flower and pseudostem: dietary fiber and associated antioxidant capacity. J Agric Food Chem, 60: 427- 432. Binsack R, Boersma BJ, Patel RP, Kirk M, White CR, Darley-Usmar V, Barnes S, Zhou F, Parks DA. 2001. Enhanced antioxidant activity after chlorination of Ferrari AJP, Vol. 13, No. 3, May-Jun 2023 250 quercetin by hypochlorous acid. Alcohol Clin Exp Res, 25: 434-443. Borah M, Das S. 2017. Antidiabetic, antihyperlipidemic, and antioxidant activities of Musa balbisiana Colla. in type 1 diabetic rats. Indian J Pharmacol, 49: 71-76. Caimi G, Canino B, Montana M, Urso C, Calandrino V, Lo Presti R, Hopps E. 2019. Lipid peroxidation, protein oxidation, gelatinases, and their inhibitors in a group of adults with obesity. Horm Metab Res, 51: 389-395. Carnevale R, Loffredo L, Nocella C, Bartimoccia S, Bucci T, De Falco E, Peruzzi M, Chimenti I, Biondi-Zoccai G, Pignatelli P, Violli F, Frati G. 2014. Epicatechin and catechin modulate endothelial activation induced by platelets of patients with peripheral artery disease. Oxid Med Cell Longev, 2014: 691015. China R, Dutta S, Sen S, Chakrabarti R, Bhowmik D, Ghosh S, Dhar P. 2011. In vitro antioxidant activity of different cultivars of banana flower (Musa paradicicus L.) extracts available in India. J Food Sci, 76: C1292-C1299. Chistiakov DA, Melnichenko AA, Myasoedova VA, Grechko AV, Orekhov AN. 2017. Mechanisms of foam cell formation in atherosclerosis. J Mol Med, 95: 1153-1165. Chung RWS, Leanderson P, Lundberg AK, Jonasson L. 2017. Lutein exerts antiinflammatory effects in patients with coronary artery disease. Atherosclerosis, 262: 87-93. Cressey R, Kumsaiyai W, Mangklabruks A. 2014. Daily consumption of banana marginally improves blood glucose and lipid profile in hypercholesterolemic subjects and increases serum adiponectin in type 2 diabetic patients. Indian J Exp Biol, 52: 1173-1181. Darsini DTP, Maheshu V, Vishnupriya M, Sasikumar JM. 2012. In vitro antioxidant activity of banana (Musa spp. ABB cv. Pisang Awak). Indian J Biochem Biophys, 49: 124-129. Dikshit P, Tyagi MK, Shukla K, Gambhir JK, Shukla R. 2016. Antihypercholesterolemic and antioxidant effect of sterol rich methanol extract of stem of Musa sapientum (banana) in cholesterol fed Wistar rats. J Food Sci Technol, 53: 1690-1697. Dreschler M, Megens RTA, van Zandvoort M, Weber C, Soehnlein O. 2010. Hyperlipidemia-triggered neutrophilia promotes early atherosclerosis. Circulation, 122: 1837-1845. Dwyer JH, Navab M, Dwyer KM, Hassan K, Sun P, Shircore A, Hama-Levy S, Hough G, Wang X, Drake T, Merz CN, Fogelman AM. 2001. Oxygenated carotenoid lutein and progression of early atherosclerosis. The Los Angeles Atherosclerosis Study. Circulation, 103: 2922-2927. Edenta C, James DB, Owolabi OA, Okoduwa SIR. 2014. Hypolipidemic effects of aqueous extract of three cultivars of Musa sapientum fruit peel on poloxamer-407 induced hyperlipidemic Wistar rats. Int J Pharma Sci Res, 5: 1049-1054. Egert S, Bosy-Westphal A, Seiberl J, Kürbitz C, Settler U, Plachta-Danielzik S, Wagner AE, Frank J, Schrezenmeier J, Rimbach G, Wolffram S, Müller MJ. 2009. Quercetin reduces systolic blood pressure and plasma oxidised low-density lipoprotein concentrations in overweight subjects with a high-cardiovascular disease risk phenotype: a double-blinded, placebo-controlled cross-over study. Br J Nutr, 102: 1065-1074. Englberger L, Lyons G, Foley W, Daniells J, Aalbersberg B, Dolodolotawake U, Watoto C, Iramu E, Taki B, Wehi F, Warito P, Taylor M. 2010. Carotenoid and riboflavin content of banana cultivars from Makira, Solomon islands. J Food Composit Anal, 23: 624-632. Esterbauer H. 1993. Cytotoxicity and genotoxicity of lipid-oxidation products. Am J Clin Nutr, 57: S779-S786. Ferrari CKB. 1998. Lipid oxidation in foods and biological systems: general mechanisms and nutritional and pathological implications. Rev Nutr, 11: 3-14. Ferrari CKB. 2004. Functional foods, herbs and nutraceuticals: towards biochemical mechanisms of healthy aging. Biogerontology, 5: 275-289. Ferrari CKB. 2013. Functional foods, nutraceuticals, and herbs: an approach of cell and molecular anti-ageing mechanisms. Agro Food Ind High Tech, 24: 10-12. Banana and cardiovascular protection AJP, Vol. 13, No. 3, May-Jun 2023 251 Ferrari CKB, Torres EAFS. 2003. Biochemical pharmacology of functional foods and prevention of chronic diseases of aging. Biomed Pharmacother, 57: 251-260. Ferrari CKB, França EL, Honorio-França AC. 2009. Nitric oxide, health and disease. J Appl Biomed, 7: 163-173. Ferrari CKB, Percário S, Silva JCCB, Torres EAFS. 2016. An apple plus a nut a day keeps the doctors away: antioxidant capacity of foods and their health benefits. Cur Pharm Des, 22: 189-195. Ferrari CKB. 2020. Anti-atherosclerotic and cardiovascular protective benefits of Brazilian nuts. Front Biosci, 12: 38-56. Gaudreault N, Kumar N, Olivas VR, Eberlé D, Stephens K, Raffai RL. 2013. Hyperglycemia impairs atherosclerosis regression in mice. Am J Pathol, 183: 1981-1992. Gutteridge JM. 1995. Lipid peroxidation and antioxidants as biomarkers of tissue damage. Clin Chem, 41: 1819-1828. Gutteridge JMC, Halliwell B. 2018. Minireview: oxidative stress, redox stress or redox success? Biochem Biophys Res Commun, 502: 183-186. Han H, Cui W, Wang L, Xiong Y, Liu L, Sun X, Hao L. 2015. Lutein prevents high fat diet-induced atherosclerosis in ApoEdeficient mice by inhibiting NADPH oxidase and increasing PPAR expression. Lipids, 50: 261-273. Heng Z, Sheng O, Yan S, Hongxian L, Motorykin I, Gao H, Li C, Yang Q, Hu C, Kuang R, Bi F, Dou T, Xie S, Deng G, Yi G. 2017. Carotenoid profiling in the peel and pulp of 36 selected Musa varieties. Food Sci Technol Res, 23: 603-611. Housseini M, Boskabady MH, Khazdair MR. 2021. Neuroprotective effects of Coriandrum sativum and its constituent, linalool: a review. Avicenna J Phytomed, 11: 436-450. Howard AN, Thurnham DI. 2017. Lutein and atherosclerosis: Belfast versus Toulouse revisited. Med Hypoth, 98: 63-68. Hwang SJ, Kim Y-W, Park Y, Lee H-J, Kim K-W. 2014. Anti-inflammatory effects of chlorogenic acid in lipopolysaccharidestimulated RAW 264.7 cells. Inflam Res, 63: 81-90. Ignarro LJ. 2002. Wein Lun visiting professor lecture: Nitric oxide in the regulation of vascular function: a historical overview. J Card Surg, 17: 301-306. Izar MCD, Costa ES, França CN, Fonseca FAH, Kato J, Bianco HT, Freitas T, Fonseca HAR, Figueiredo-Neto AM. 2018. Beneficial effects of green banana biomass consumption in patients with prediabetes and diabetes: a randomized controlled trial. Atherosclerosis, 275: e196. Kahlon TS, Smith GE. 2007. In vitro binding of bile acids by bananas, peaches, pineapple, grapes, pears, apricots and nectarines. Food Chem, 101: 1046-1051. Kandasamy S, Aradhya SM. 2014. Polyphenolic profile and antioxidant properties of rhizome of commercial banana cultivars grown in India. Food Biosci, 8: 22-32. Kanazawa K, Sakakibara H. 2000. High content of dopamine, a strong antioxidant, in Cavendish banana. J Agric Food Chem, 48: 844-848. Kandasamy S, Ramu S, Aradhya SM. 2016. In vitro functional properties of crude extracts and isolated compounds from banana pseudostem and rhizome. J Sci Food Agric, 96: 1347-1355. Kanner J. 1994. Oxidative processes in meat and meat products: quality implications. Meat Sci, 36: 169-189. Krishnan K, Vijayalakshmi NR. 2005. Alterations in lipids & lipid peroxidation in rats fed with flavonoid rich fraction of banana (Musa paradisiaca) from high background radiation area. Indian J Med Res, 122: 540-546. Kulma A, Szopa J. 2007. Cathecolamines are active compounds in plants. Plant Sci, 172: 433-440. Kurano M, Hasegawa K, Kunimi M, Hara M, Yatomi Y, Teramoto T, Tsukamoto K. 2018. Sitosterol prevents obesity-related chronic inflammation. Biochim Biophys Acta Mol Cel Biol Lip, 1863: 191-198. Lei L, Zhu H, Zhang C, Wang X, Ma KY, Wang L, Zhao Y, Chen Z-Y. 2017. Dietary β-sitosterol is more potent in reducing plasma cholesterol than sesamin in hypercholesterolemia hamsters. Eur J Lipid Sci Technol, 119: 1600349. Lobo V, Patil A, Phatak A, Chandra N. 2010. Free radicals, antioxidants and functional foods: impact on human health. Pharmacogn Rev, 4: 118-126. López GB, Montano FJG. 2014. Propiedades Ferrari AJP, Vol. 13, No. 3, May-Jun 2023 252 funcionales del plátano (Musa sp). Rev Med UV, 14: 22-26. Lorenz M, Fechner M, Kalkowski J, Fröhlich K, Trautmann A, Böhm V, Liebisch G, Lehneis S, Schmitz G, Ludwig A, Baumann G, Stangl K, Stangl V. 2012. Effects of lycopene on the initial stage of atherosclerosis in New Zealand White (NZW) rabbits. PLOS One, 7: e30808. Ludovici V, Barthelmes J, Nägele MP, Flammer AJ, Sudano I. 2018. Polyphenols: anti-platelet nutraceutical? Curr Pharm Des, 24: 146-157. Marinovic MP, Morandi AC, Otton R. 2015. Green tea catechins alone or in combination alter functional parameters of human neutrophils via suppressing the activation of TLR-4/NFkB p65 signal pathway. Toxicol in Vitro, 29: 1766- 1778. Mokbel MS, Hashinaga F. 2005. Antibacterial and antioxidant activities of Banana (Musa, AAA cv. Cavendish) fruits peel. Am J Biochem Biotechnol, 1: 125-131. Moongngarm A, Tiboonbun W, Sanpong M, Sriwong P, Phiewtong L, Prakitrum R, Huychan N. 2014. Resistant starch and bioactive contents of unripe banana flour as influenced by harvesting periods and its application. Am J Agric Biol Sci, 9: 457-465. Mosa ZM, Khalil AF. 2015. The effect of banana peels supplemented diet on acute liver failure rats. Ann Agricult Sci, 60: 373-379. Moss JWE, Ramji DP. 2016. Nutraceutical therapies for atherosclerosis. Nat Rev Cardiol, 13: 513-532. Navghare VV, Dhawale SC. 2017. In vitro antioxidant, hypoglycemic and oral glucose tolerance test of banana peels. Alexandria J Med, 53: 237-243. Nguyen D, Nováková A, Spurná K, Hričko J, Phung H, Viktorová J, Stránska M, Hajšlová M, Rumi T. 2017. Antidiabetic compounds in stem juice from banana. Czech J Food Sci, 35: 407-413. Orekhov AN, Sobenin IA, Korneev NV, Kirichenko TV, Myasoedova VA, Melnichenko AA, Balcells M, Edelman ER, Bobryshev YV. 2013. Antiatherosclerotic therapy based on botanicals. Recent Pat Cardiovasc Disc, 8: 56-66. Orekhov AN. 2013. Direct anti-atherosclerotic therapy; Development of natural antiatherosclerotic drugs preventing cellular cholesterol retention. Curr Pharm Des, 19: 5909-5928. Palozza P, Parrone N, Simone RE, Catalano E. 2010. Lycopene in atherosclerosis prevention: an integrated scheme of the potential mechanisms of action from cell culture studies. Arch Biochem Biophys, 501: 26-33. Pannala AS, Rice-Evans CA, Halliwell B, Singh S. 1997. Inhibition of peroxynitritemediated tyrosine nitration by catechin and polyphenols. Biochem Biophys Res Commun, 232: 164-168. Park J-G, Oh GT. 2011. The role of peroxidases in the pathogenesis of atherosclerosis. BMB Rep, 44: 497-505. Patel R, Rinker L, Peng J, Chilian WM. 2017. Reactive oxygen species: the good and the bad. In: Cristiana F, Albu E (Eds.). Reactive oxygen species in living cells, pp.7-20, London, IntechOpen. Pereira A, Maraschin M. 2015. Banana (Musa spp) from peel to pulp: ethnopharmacology, source of bioactive compounds and its relevance for human health. J Ethnopharmacol, 160: 149-163. Pfeuffer M, Auinger A, Bley U, KrausStojanowic I, Laue C, Winkler P, Rüfer CE, Frank J, Bösch-Saadatmandi C, Rimbach G, Schrezenmeier J. 2013. Effect of quercetin on traits of the metabolic syndrome, endothelial function and inflammation in men with different APOE isoforms. Nutr Metab Cardiovasc Dis, 23: 403-409. Pignatelli P, Di Santo S, Buchetti B, Brunelli A, Violi F. 2006. Polyphenols enhance platelet nitric oxide by inhibiting protein kinase C-dependent NADPH oxidase activation: effect on platelet recruitment. Faseb J, 20: 1082-1089. Rahman MM, Kabir SMH. 2003. In: Asiatic Society of Bangladesh (Ed.), Banglapedia, Dhaka, p.403. Rajagopalan S, Meng XP, Ramasamy S, Harrison DG, Galis ZS. 1996. Reactive oxygen species produced by macrophagederived foam cells regulate the activity of vascular matrix metalloproteinases in vitro. Implications for atherosclerotic plaque stability. J Clin Invest, 98: 2572- 2579. Rebello LPG, Ramos AM, Pertuzatti PB, Banana and cardiovascular protection AJP, Vol. 13, No. 3, May-Jun 2023 253 Barcia MT, Castillo-Muñoz N, HermosínGutiérrez I. 2014. Flour of banana (Musa AAA) peel as source of antioxidant phenolic compounds. Food Res Int, 55: 397-403. Riccioni G, Mancini B, Di Ilio E, Bucciarelli T, D‟Orazio N. 2008. Protective effect of lycopene in cardiovascular disease. Eur Rev Med Pharm Sci, 12: 183-190. Ried K, Fakler P. 2011. Protective effect of lycopene on serum cholesterol and blood pressure: meta-analyses of intervention trials. Maturitas, 68: 299-310. Rissanen T, Voutilainen S, Nyyssönen K, Salonen JT. 2002. Lycopene, atherosclerosis, and coronary heart disease. Exp Biol Med, 227: 900-907. Shirzad F, Morovatdar N, Rezaee R, Tsarouhas K, Moghaddam AA. 2021. Cinnamon effects on blood pressure and metabolic profile: A double-blind, randomized, placebo-controlled trial in patients with stage 1 hypertension. Avicenna J Phytomed, 11: 91-100. Sidhu JS, Zafar TA. 2018. Bioactive compounds in banana fruits and their health benefits. Food Qual Safet, 2: 183- 188. Silvestre AJD. 2014. Lipophilic phytochemicals form banana fruits from several species. Food Chem, 162: 247- 252. Sobenin IA, Chistiakov DA, Bobryshev YV, Postnov AY, Orekhov AN. 2013. Blood atherogenicity as a target for antiatherosclerotic therapy. Curr Pharm Des, 19: 5954-5962. Someya S, Yoshiki Y, Okubo K. 2002. Antioxidant compounds from bananas (Musa Cavendish). Food Chem, 79: 351- 354. Stein JH, Keevil JG, Wiebe DA, Aeschliman S, Folts JD. 1999. Purple grape juice improves endothelial function and reduces the susceptibility of LDL cholesterol to oxidation in patients with coronary artery disease. Circulation, 100: 1050-1055. Steinberg D, Parthasarathy S, Carew TE, Khoo JC, Witztum JL. 1989. Beyond cholesterol: modifications of low-density lipoprotein that increase its atherogenicity. New Engl J Med, 320: 915-924. Suwanaruang T. 2016. Analysing lycopene content in fruits. Agric Agricult Sci Procedia, 11: 46-48. Tajik N, Tajik M, Mack I, Enck P. 2017. The potential effects of chlorogenic acid, the main phenolic components in coffee, on health: a comprehensive review of the literature. Eur J Nutr, 56: 2215-2244. Thanaraj T, Terry LA. 2011. Tropical fruit (Banana, pineapple, papaya and mango). In: Terry LA (Ed.). Health-promoting properties of fruit and vegetables, pp.352- 370. Oxfordshire, CAB Int. Tertov W, Orekhov AN, Martsenyuk ON, Perova NV, Smirnov VN. 1989. Lowdensity lipoproteins isolated from the blood of patients with coronary heart disease induce the accumulation of lipids in human aortic cells. Exp Mol Pathol, 50: 337-347. Toh PY, Leong FS, Chang SK, Khoo HE, Yim HS. 2016. Optimization of extraction parameters on the antioxidant properties of banana waste. Acta Sci Pol Technol Aliment, 15: 65-78. Tsamo CVP, Herent M-F, Tomekpe K, Emaga TH, Quetin-Leclercq J, Rogez H, Larondelle Y, Andre C. 2015. Phenolic profiling in the pulp and peel of nine plantain cultivars. Food Chem, 167: 197- 204. Vijayakumar S, Presannakumar G, Vijayalakshmi NR. 2008. Antioxidant activity of banana flavonoids. Fitoterapia, 79: 279-282. Vilela C, Santos SAO, Villaverde JJ, Oliveira L, Nunes A, Cordeiro N, Freire CSR, Yang J, Liu RH, Halim L. 2009. Antioxidant and antiproliferative activities of common edible nut seeds. LWT Food Sci Technol, 42: 1-8. Waddingtol E, Puddey IB, Croft KD. 2004. Red wine polyphenolic compounds inhibit atherosclerosis in apolipoprotein E-deficient mice independently of effects on lipid peroxidation. Am J Clin Nutr, 79: 54-61. Wang MX, Jiao JH, Li ZY, Liu RR, Shi Q, Ma L. 2013. Lutein supplementation reduces plasma lipid peroxidation and C-reactive protein in healthy nonsmokers. Atherosclerosis, 227: 380-385. Xu X-R, Zou Z-Y, Huang Y-M, Xiao X, Ma L, Lin X-M. 2012. Serum carotenoids in relation to risk factors for development of atherosclerosis. Clin Biochem, 45: 1357- Ferrari AJP, Vol. 13, No. 3, May-Jun 2023 254 1361. Yarahmadi A, Sarabi MM, Sayahi A, Zal F. 2021. Protective effects of quercetin against hyperglycemia-induced oxidative stress in hepatic HepG2 cell line. Avicenna J Phytomed, 11: 269-280. Youryon P, Supapvanich S. 2017. Physicochemical quality and antioxidant changes in „Leb Mue Nang‟ banana fruit during ripening. Agricult Nat Res, 51: 47- 52. Zhang H, Tsao R. 2016. Dietary polyphenols: oxidative stress and antioxidant and antiinflammatory effects. Curr Opin Food Sci, 8: 33-42. Zou Z-Y, Xu X-R, Lin X-M, Zhang H-B, Xiao X, Ouyang L, Huang Y-M, Wang X, Liu Y-Q. 2014. Effects of lutein and lycopene on carotid intima-media thickness in Chinese subjects with subclinical atherosclerosis: a randomized, doubleblind, placebo-controlled trial. Brit J Nutr, 111: 474-480. | ||
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