Advanced Nasopharyngeal Carcinoma with Generalized Lymphadenopathy Masquerade as Lymphoma | ||
Iranian Journal of Otorhinolaryngology | ||
دوره 34، شماره 3، مرداد و شهریور 2022، صفحه 205-211 اصل مقاله (724.92 K) | ||
نوع مقاله: Case Report | ||
شناسه دیجیتال (DOI): 10.22038/ijorl.2022.62088.3133 | ||
نویسندگان | ||
V Sha Kri Eh Dam* 1؛ Nasibah Mohamad2؛ Izyan Rifhana Muhamad3؛ Al Duais Saleh Abdul Kadir Saeed3؛ Wan Faiziah Wan Abdul Rahman4؛ Faezahtul Arbaeyah Hussain3؛ Azlan Husin5؛ Norhafiza Mat Lazim1 | ||
1Department of Otorhinolaryngology-Head & Neck Surgery, School of Medical Sciences, University Sains Malaysia Health Campus, 16150 Kota Bharu, Kelantan, Malaysia. | ||
2Department of Radiology, School of Medical Sciences, University Sains Malaysia, Health Campus, 16150 Kota Bharu, Kelantan, Malaysia. | ||
3Department of Pathology, School of Medical Sciences, University Sains Malaysia, Health Campus, 16150 Kota Bharu, Kelantan, Malaysia. | ||
4Department of Pathology, School of Medical Sciences, Universiti Sains Malaysia, Health Campus, 16150 Kota Bharu, Kelantan, Malaysia. | ||
5Department of Internal Medicine, School of Medical Sciences, University Sains Malaysia, Health Campus, 16150 Kota Bharu, Kelantan, Malaysia. | ||
چکیده | ||
Introduction: Nasopharyngeal carcinoma (NPC) is a nasopharyngeal epithelial neoplasm that has distinct aetiological, epidemiological and biological characteristics compared to other head and neck malignancies. Patients usually present late due to non-specific symptoms and deep location of the tumour in the nasopharynx. Case Report We would like to highlight a case of advanced NPC presenting with generalised lymphadenopathy, without the presence of an obvious nasopharyngeal mass that masqueraded as lymphoma in the initial stage. Conclusions: NPC may share clinical features with other sinonasal pathologies or other malignant lymphoproliferative disorders that lead to a delay in diagnosis. NPC should be one of the differential diagnoses for any cases presenting with cervical lymphadenopathy, especially in adult male patients originating from East or Southeast Asia. Early diagnosis and treatment are crucial because early-stage NPC has an excellent chemoradiotherapy response and high survival rate. | ||
کلیدواژهها | ||
Generalized lymphadenopathy؛ Nasopharyngeal carcinoma؛ Neck metastases؛ lymphoma | ||
مراجع | ||
nasopharyngeal carcinoma: a meta-analysis of clinical evidence. BMC Cancer. 2012; 12:98. doi:10.1186/1471-2407- 12-98.
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