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Alinejad, Samira, Chahkandi, Tayyebeh, mehrpour, omid, Brent, Jeffrey, Riahi, Seyed Mohammad. (1401). Epidemiology of Pediatric Acute Poisoning in Iran: A Systematic Review and Meta-Analysis. , 10(5), 16082-16100. doi: 10.22038/ijp.2021.55738.4416
Samira Alinejad; Tayyebeh Chahkandi; omid mehrpour; Jeffrey Brent; Seyed Mohammad Riahi. "Epidemiology of Pediatric Acute Poisoning in Iran: A Systematic Review and Meta-Analysis". , 10, 5, 1401, 16082-16100. doi: 10.22038/ijp.2021.55738.4416
Alinejad, Samira, Chahkandi, Tayyebeh, mehrpour, omid, Brent, Jeffrey, Riahi, Seyed Mohammad. (1401). 'Epidemiology of Pediatric Acute Poisoning in Iran: A Systematic Review and Meta-Analysis', , 10(5), pp. 16082-16100. doi: 10.22038/ijp.2021.55738.4416
Alinejad, Samira, Chahkandi, Tayyebeh, mehrpour, omid, Brent, Jeffrey, Riahi, Seyed Mohammad. Epidemiology of Pediatric Acute Poisoning in Iran: A Systematic Review and Meta-Analysis. , 1401; 10(5): 16082-16100. doi: 10.22038/ijp.2021.55738.4416

Epidemiology of Pediatric Acute Poisoning in Iran: A Systematic Review and Meta-Analysis

International Journal of Pediatrics
دوره 10، شماره 5، مرداد 2022، صفحه 16082-16100    اصل مقاله (1.1 M)
نوع مقاله: systematic review
شناسه دیجیتال (DOI): 10.22038/ijp.2021.55738.4416
نویسندگان
Samira Alinejad1؛ Tayyebeh Chahkandi2؛ omid mehrpour3؛ Jeffrey Brent4؛ Seyed Mohammad Riahi* 5
1Pediatric Resident, Department of Pediatrics, Faculty of Medicine, Birjand University of Medical Sciences, Birjand, Iran.
2Birjand atherosclerosis and coronary artery research center, Assistante professor of pediatric
3Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ, USA.
4School of Medicine, University of Colorado, Aurora, CO, USA
5Cardiovascular Diseases Research Center, Department of Epidemiology and Biostatistics, School of Medicine, Birjand University of Medical Sciences, Birjand, Iran
چکیده
Background: The epidemiology of pediatric poisoning differs from one country to another. Due to the scarcity of reviews on this issue in Iran, we performed a systematic review and meta-analysis of studies providing data on Iranian pediatric poisoning epidemiology.
Methods: PubMed, Web of Sciences, Science direct, Embase, Scopus and the Persian databases Magiran, Scientific Information Database (SID), and Iranmedex were searched. Twenty-seven studies published between 2002 and 2019 were included, based on the inclusion and exclusion criteria.
Results: 54.7% of the participants in the reviewed studies were male, and 88.1% of them were unintentional. Most of the children were in the age range of 3-5 years. Non-pharmaceutical agents were the most common causes of poisonings (n=7175, 59.2%) and among them, illicit drugs (19.3%) followed by hydrocarbons (16.4%) constituted the most common non-pharmaceutical poisonings. Illicit drugs, especially opioids, showed an upward trend from 2002 to 2019. Among pharmaceuticals, central nervous system (CNS) drugs (50.4%), especially benzodiazepines (BZDs) (25.8%) and analgesics (14.5%), were the most frequent agents implicated. CNS complaints (51.8%), followed by gastrointestinal complaints (27.6%), were the most common symptoms. Ingestion was the most common route of poisoning (22.1%). Most of the poisoning cases occurred in summer (28.2%). 21.7% of the cases were hospitalized and the mortality rate was 0.8%. A remarkable downward trend in both hospitalization and death rates occurred over time.
Conclusion: Overall, non-pharmaceutical toxicity was found to be the most common cause of poisoning. However, considering the agents separately, pharmaceuticals, illicit drugs, and hydrocarbons were the most common causes of poisoning, respectively. In contrast to the decreasing trend in hydrocarbons, pesticides, and pharmaceutical poisonings, we found an increase in opioid poisoning during our study period.
کلیدواژه‌ها
prevalence؛ children؛ intoxication؛ Iran
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