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KAUR, GURPREET, Srivastava, Anoop, Garg, Pardeep, Singh Kang, Manraj, Grover, Romikant, Gaur, Garima, Sheetal, Sheetal, Dangwal, Vinod. (1401). A Comparative Analysis of Different Prescription Points in High Dose Rate Brachytherapy of Cervical Cancer. , 19(4), 234-240. doi: 10.22038/ijmp.2022.58066.1972
GURPREET KAUR; Anoop Kumar Srivastava; Pardeep Garg; Manraj Singh Kang; Romikant Grover; Garima Gaur; Sheetal Sheetal; Vinod Kumar Dangwal. "A Comparative Analysis of Different Prescription Points in High Dose Rate Brachytherapy of Cervical Cancer". , 19, 4, 1401, 234-240. doi: 10.22038/ijmp.2022.58066.1972
KAUR, GURPREET, Srivastava, Anoop, Garg, Pardeep, Singh Kang, Manraj, Grover, Romikant, Gaur, Garima, Sheetal, Sheetal, Dangwal, Vinod. (1401). 'A Comparative Analysis of Different Prescription Points in High Dose Rate Brachytherapy of Cervical Cancer', , 19(4), pp. 234-240. doi: 10.22038/ijmp.2022.58066.1972
KAUR, GURPREET, Srivastava, Anoop, Garg, Pardeep, Singh Kang, Manraj, Grover, Romikant, Gaur, Garima, Sheetal, Sheetal, Dangwal, Vinod. A Comparative Analysis of Different Prescription Points in High Dose Rate Brachytherapy of Cervical Cancer. , 1401; 19(4): 234-240. doi: 10.22038/ijmp.2022.58066.1972

A Comparative Analysis of Different Prescription Points in High Dose Rate Brachytherapy of Cervical Cancer

Iranian Journal of Medical Physics
مقاله 5، دوره 19، شماره 4، مهر و آبان 2022، صفحه 234-240    اصل مقاله (1.37 M)
نوع مقاله: Original Paper
شناسه دیجیتال (DOI): 10.22038/ijmp.2022.58066.1972
نویسندگان
GURPREET KAUR1؛ Anoop Kumar Srivastava2؛ Pardeep Garg1؛ Manraj Singh Kang1؛ Romikant Grover1؛ Garima Gaur1؛ Sheetal Sheetal3؛ Vinod Kumar Dangwal* 4
1Department of Radiation Oncology, Guru Gobind Singh Medical College and Hospital, Faridkot, India
2Department of Radiation Oncology, Dr. Ram Manohar Lohia Institute of Medical Sciences, Vibhuti Khand Gomti Nagar, Lucknow -226010 India
3Advance Cancer Centre, Bathinda, Punjab
4Department of Radiation Oncology, Govt. Medical College, Patiala, India
چکیده
Introduction: The dose prescription point in high dose rate (HDR) intracavitory brachytherapy (ICBT) of cervical cancer is Manchester point A but the localization of this point has a wider variation. To minimize these variations, the American Brachytherapy Society (ABS) introduced a new definition of point A and named it as point H. In this study, these two points have been compared in terms of dosimetric parameters.
Material and Methods: Twenty HDR ICBT of cervical cancer patients were retrospectively evaluated with Manchester point A and ABS point H. Target volume covered by prescribed dose (TV), dose to 2cc (D2cc) of the bladder and rectum were noted for both points. Statistical analysis using a two-tailed paired t-test was performed to compare dosimetric parameters of both the points of prescription. The maximum value, minimum value, and mean ± standard deviation along with the p value have been noted.
Results: On average, point H was 4.0mm ± 6.4mm shifted (superior/inferior) from point A, along the tandem direction. The average TV when the prescription was done at point H (TVH) was 33.7cc ± 10.1cc which was higher than the average TV when the prescription was done at point A (TVA) of 33.3cc ± 9.4 cc.D2cc increased from 63% ± 23% to 68% ± 24% for the rectum and 52% ± 18% to 56% ± 20% for the bladder when the prescription point changed from A to H.
Conclusion: As observed, average TV, D2cc of the bladder, and rectum were higher in the case of point H prescription plan (PH) as compared with point A prescription plan (PA). The dose difference between PH and PA was found to be statistically significant, so careful consideration is needed to implementation of new point H in clinical practice.
کلیدواژه‌ها
Cervical Cancer؛ High Dose Rate؛ Brachytherapy؛ Manchester Point A؛ ABS Point H
مراجع
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