سامانه مدیریت نشریات علمی دانشگاه علوم پزشکی مشهد

Sacchetti, Federico, Kilian, Raphael, Muratori, Francesco, Cherix, Stephane, Foschi, Lorenzo, Morganti, Riccardo, Campanacci, Domenico, Capanna, Rodolfo. (1401). The Performances of Conventional Titanium and Silver-Coated Megaprostheses in Non-oncological and Post-oncological Patients: An Analysis of Infection Failures in 142 Patients. , 10(5), 439-446. doi: 10.22038/abjs.2021.58351.2889
Federico Sacchetti; Raphael Kilian; Francesco Muratori; Stephane Cherix; Lorenzo Foschi; Riccardo Morganti; Domenico Andrea Campanacci; Rodolfo Capanna. "The Performances of Conventional Titanium and Silver-Coated Megaprostheses in Non-oncological and Post-oncological Patients: An Analysis of Infection Failures in 142 Patients". , 10, 5, 1401, 439-446. doi: 10.22038/abjs.2021.58351.2889
Sacchetti, Federico, Kilian, Raphael, Muratori, Francesco, Cherix, Stephane, Foschi, Lorenzo, Morganti, Riccardo, Campanacci, Domenico, Capanna, Rodolfo. (1401). 'The Performances of Conventional Titanium and Silver-Coated Megaprostheses in Non-oncological and Post-oncological Patients: An Analysis of Infection Failures in 142 Patients', , 10(5), pp. 439-446. doi: 10.22038/abjs.2021.58351.2889
Sacchetti, Federico, Kilian, Raphael, Muratori, Francesco, Cherix, Stephane, Foschi, Lorenzo, Morganti, Riccardo, Campanacci, Domenico, Capanna, Rodolfo. The Performances of Conventional Titanium and Silver-Coated Megaprostheses in Non-oncological and Post-oncological Patients: An Analysis of Infection Failures in 142 Patients. , 1401; 10(5): 439-446. doi: 10.22038/abjs.2021.58351.2889

The Performances of Conventional Titanium and Silver-Coated Megaprostheses in Non-oncological and Post-oncological Patients: An Analysis of Infection Failures in 142 Patients

The Archives of Bone and Joint Surgery
مقاله 10، دوره 10، شماره 5، مرداد 2022، صفحه 439-446    اصل مقاله (560.08 K)
نوع مقاله: RESEARCH PAPER
شناسه دیجیتال (DOI): 10.22038/abjs.2021.58351.2889
نویسندگان
Federico Sacchetti* 1؛ Raphael Kilian2؛ Francesco Muratori3؛ Stephane Cherix4؛ Lorenzo Foschi3؛ Riccardo Morganti1؛ Domenico Andrea Campanacci3؛ Rodolfo Capanna1
1Department of Orthopaedic and Trauma Surgery, University of Pisa, Italy
2Department of Ophtalmology, Azienda Ospedaliera Universitaria Integrata, Verona, Italy
3Department of Oncology and Surgery at Robotic Address of the Hospital Careggi University of Florence, Firenze FI, Italy
4Department of Orthopaedic and Trauma Surgery, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
چکیده
Background: Megaprostheses are one of the preferred choices of reconstruction after tumor resection. Periprosthetic 
joint infections are one of the most serious complications of joint prostheses surgeries. In this study, our aim was to 
analyze the efficacy of silver-coated megaprostheses in reducing the risk of prosthesis-related infection.
Methods: One hundred forty-two patients who had undergone implantation of a mega-endoprosthesis for nonneoplastic or post-neoplastic conditions were included in this retrospective study. The end-point of the survival analysis 
was the prosthesis failure due to infection. 
Results: Thirty-eight patients had undergone implantation of a silver-coated megaprosthesis and 104 patients a 
megaprosthesis without silver coating. The survival analysis showed an overall infection-free survival rate of 82.3% at 
five years and 61.9% at 10 years. Silver-coated prostheses had an HR of 0.72 (95% CI: 0.26-2.05; P=0.54).
Conclusion: Implantation of a silver-coated mega-prosthesis in non-oncological patients did not significantly reduce 
the risk of prosthesis-related infection.
Level of evidence: III
کلیدواژه‌ها
Endoprosthesis؛ Infection؛ Megaprosthesis؛ Periprosthetic infection؛ Silver؛ Silver-coated
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